Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1836
  Reference Plasmid   1111525849663039_bin.26__k141_376701
  Reference Plasmid Size   15077
  Reference Plasmid GC Content   0.52
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0018304 MHNHNBKO_00002 4914 14 Skin 0.70 protein_coding upstream_gene_variant MODIFIER -3018T>G None
M0018305 MHNHNBKO_00006 6542 11 Skin 0.55 protein_coding synonymous_variant LOW 36A>G Leu12Leu
M0018306 MHNHNBKO_00005 4773 3 Skin 0.15 protein_coding synonymous_variant LOW 66C>T Ala22Ala
M0018307 MHNHNBKO_00005 4800 3 Skin 0.15 protein_coding synonymous_variant LOW 39T>C Pro13Pro
M0018308 MHNHNBKO_00005 4829 3 Skin 0.15 protein_coding missense_variant MODERATE 10A>T Thr4Ser
M0018309 MHNHNBKO_00002 4850 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2954A>G None
M0018310 MHNHNBKO_00002 4851 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2955C>T None
M0018311 MHNHNBKO_00002 4866 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2970C>G None
M0018312 MHNHNBKO_00002 4895 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2999A>T None
M0018313 MHNHNBKO_00002 4919 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -3023T>G None
M0018314 MHNHNBKO_00011 15024 5 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -3443C>G None
M0018315 MHNHNBKO_00014 14895 3 Skin 0.15 protein_coding synonymous_variant LOW 90T>C Asp30Asp
M0018316 MHNHNBKO_00014 14904 3 Skin 0.15 protein_coding synonymous_variant LOW 81T>G Ser27Ser
M0018317 MHNHNBKO_00014 14916 3 Skin 0.15 protein_coding synonymous_variant LOW 69A>G Lys23Lys
M0018318 MHNHNBKO_00014 14928 3 Skin 0.15 protein_coding synonymous_variant LOW 57C>A Arg19Arg
M0018319 MHNHNBKO_00014 14931 3 Skin 0.15 protein_coding synonymous_variant LOW 54A>C Arg18Arg
M0018320 MHNHNBKO_00014 14937 3 Skin 0.15 protein_coding synonymous_variant LOW 48T>G Ala16Ala
M0018321 MHNHNBKO_00014 14946 3 Skin 0.15 protein_coding synonymous_variant LOW 39T>C His13His
M0018322 MHNHNBKO_00014 14973 3 Skin 0.15 protein_coding synonymous_variant LOW 12G>A Ala4Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
MHNHNBKO_00010 8.A.5.1.7 76.2 1.1e-137 1 298 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.5 The Voltage-gated K+ Channel β-subunit (Kvβ) Family