Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1852
  Reference Plasmid   1111525849663614_bin.93__k141_187775
  Reference Plasmid Size   3442
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0018916 FCLIOPKA_00003 2805 3 Skin 0.30 protein_coding synonymous_variant LOW 126G>A Leu42Leu
M0018917 FCLIOPKA_00003 2837 5 Skin 0.50 protein_coding missense_variant MODERATE 94A>C Lys32Gln
M0018918 FCLIOPKA_00003 2910 3 Skin 0.30 protein_coding synonymous_variant LOW 21C>T Thr7Thr
M0018919 FCLIOPKA_00004 3071 3 Skin 0.30 protein_coding missense_variant MODERATE 229G>A Val77Ile
M0018920 FCLIOPKA_00004 3180 3 Skin 0.30 protein_coding synonymous_variant LOW 120A>G Gln40Gln
M0018921 FCLIOPKA_00004 3213 6 Skin 0.60 protein_coding missense_variant MODERATE 87C>A His29Gln
M0018922 FCLIOPKA_00004 3218 6 Skin 0.60 protein_coding missense_variant MODERATE 82A>G Lys28Glu
M0018923 FCLIOPKA_00001 3330 6 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -993T>C None
M0018924 FCLIOPKA_00001 3386 6 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1049A>G None
M0018925 FCLIOPKA_00001 595 4 Skin 0.40 protein_coding downstream_gene_variant MODIFIER *234T>C None
M0018926 FCLIOPKA_00001 604 4 Skin 0.40 protein_coding downstream_gene_variant MODIFIER *225C>T None
M0018927 FCLIOPKA_00001 607 4 Skin 0.40 protein_coding downstream_gene_variant MODIFIER *222A>G None
M0018928 FCLIOPKA_00001 610 3 Skin 0.30 protein_coding downstream_gene_variant MODIFIER *219C>A None
M0018929 FCLIOPKA_00001 622 4 Skin 0.40 protein_coding downstream_gene_variant MODIFIER *207C>T None
M0018930 FCLIOPKA_00001 652 3 Skin 0.30 protein_coding downstream_gene_variant MODIFIER *177G>A None
M0018931 FCLIOPKA_00001 664 4 Skin 0.40 protein_coding downstream_gene_variant MODIFIER *165A>G None
M0018932 FCLIOPKA_00001 1195 4 Skin 0.40 protein_coding synonymous_variant LOW 1143A>T Ala381Ala
M0018933 FCLIOPKA_00001 1567 4 Skin 0.40 protein_coding synonymous_variant LOW 771C>T His257His
M0018934 FCLIOPKA_00001 1822 4 Skin 0.40 protein_coding synonymous_variant LOW 516C>T Ile172Ile
M0018935 FCLIOPKA_00002 2491 4 Skin 0.40 protein_coding synonymous_variant LOW 165C>T His55His
M0018936 FCLIOPKA_00001 571 3 Skin 0.30 protein_coding downstream_gene_variant MODIFIER *258T>C None
M0018937 FCLIOPKA_00004 3209 3 Skin 0.30 protein_coding missense_variant MODERATE 91A>G Met31Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term