Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1853
  Reference Plasmid   1111525849663683_bin.20__k141_451657
  Reference Plasmid Size   17147
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0018938 OAGINFCH_00004 7928 11 Skin 0.85 protein_coding upstream_gene_variant MODIFIER -4993G>A None
M0018939 OAGINFCH_00004 7933 6 Skin 0.46 protein_coding upstream_gene_variant MODIFIER -4998T>G None
M0018940 OAGINFCH_00004 7935 6 Skin 0.46 protein_coding upstream_gene_variant MODIFIER -5000T>C None
M0018941 OAGINFCH_00009 9155 5 Skin 0.38 protein_coding synonymous_variant LOW 168C>T Gly56Gly
M0018942 OAGINFCH_00009 9158 8 Skin 0.62 protein_coding synonymous_variant LOW 165T>C Tyr55Tyr
M0018943 OAGINFCH_00009 9163 5 Skin 0.38 protein_coding missense_variant MODERATE 160T>A Ser54Thr
M0018944 OAGINFCH_00009 9219 4 Skin 0.31 protein_coding missense_variant MODERATE 104A>G Asp35Gly
M0018945 OAGINFCH_00009 9225 8 Skin 0.62 protein_coding missense_variant MODERATE 98T>C Val33Ala
M0018946 OAGINFCH_00009 8207 3 Skin 0.23 protein_coding synonymous_variant LOW 1116T>G Leu372Leu
M0018947 OAGINFCH_00007 7266 3 Skin 0.23 protein_coding missense_variant MODERATE 164G>C Gly55Ala
M0018948 OAGINFCH_00007 7280 4 Skin 0.31 protein_coding synonymous_variant LOW 150A>G Glu50Glu
M0018949 OAGINFCH_00004 7529 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -4594C>T None
M0018950 OAGINFCH_00005 7956 4 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -3535C>T None
M0018951 OAGINFCH_00005 7988 4 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -3567G>A None
M0018952 OAGINFCH_00009 8042 3 Skin 0.23 protein_coding synonymous_variant LOW 1281C>T Tyr427Tyr
M0018953 OAGINFCH_00009 8410 3 Skin 0.23 protein_coding missense_variant MODERATE 913A>C Thr305Pro
M0018954 OAGINFCH_00009 8435 3 Skin 0.23 protein_coding synonymous_variant LOW 888C>G Ala296Ala
M0018955 OAGINFCH_00009 8438 3 Skin 0.23 protein_coding synonymous_variant LOW 885T>C Phe295Phe
M0018956 OAGINFCH_00009 8625 3 Skin 0.23 protein_coding missense_variant MODERATE 698A>G Asp233Gly
M0018957 OAGINFCH_00009 8642 3 Skin 0.23 protein_coding synonymous_variant LOW 681A>G Gln227Gln
M0018958 OAGINFCH_00009 8669 3 Skin 0.23 protein_coding synonymous_variant LOW 654T>C His218His
M0018959 OAGINFCH_00009 8708 3 Skin 0.23 protein_coding synonymous_variant LOW 615T>C Asn205Asn
M0018960 OAGINFCH_00009 8714 3 Skin 0.23 protein_coding synonymous_variant LOW 609G>A Lys203Lys
M0018961 OAGINFCH_00009 8774 3 Skin 0.23 protein_coding synonymous_variant LOW 549G>C Thr183Thr
M0018962 OAGINFCH_00009 8777 3 Skin 0.23 protein_coding synonymous_variant LOW 546C>G Arg182Arg
M0018963 OAGINFCH_00009 8778 3 Skin 0.23 protein_coding missense_variant MODERATE 545G>A Arg182His
M0018964 OAGINFCH_00005 9323 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -4902C>A None
M0018965 OAGINFCH_00011 10466 3 Skin 0.23 protein_coding missense_variant MODERATE 347T>C Val116Ala
M0018966 OAGINFCH_00002 4429 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -3556A>C None
M0018967 OAGINFCH_00007 7061 3 Skin 0.23 protein_coding synonymous_variant LOW 369A>G Glu123Glu
M0018968 OAGINFCH_00007 7115 3 Skin 0.23 protein_coding synonymous_variant LOW 315T>C His105His
M0018969 OAGINFCH_00007 7151 3 Skin 0.23 protein_coding synonymous_variant LOW 279A>G Ala93Ala
M0018970 OAGINFCH_00007 7384 3 Skin 0.23 protein_coding synonymous_variant LOW 46C>T Leu16Leu
M0018971 OAGINFCH_00006 5134 3 Skin 0.23 protein_coding synonymous_variant LOW 312T>C Asp104Asp
M0018972 OAGINFCH_00006 5173 3 Skin 0.23 protein_coding synonymous_variant LOW 273G>C Ala91Ala
M0018973 OAGINFCH_00006 5218 3 Skin 0.23 protein_coding synonymous_variant LOW 228G>T Gly76Gly
M0018974 OAGINFCH_00009 8981 3 Skin 0.23 protein_coding synonymous_variant LOW 342T>C Gly114Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
OAGINFCH_00015 VFG011430 LPS 84.6 7.7e-31 1 78 1.0 1 Immune modulation acyl carrier protein experiment
OAGINFCH_00015 VFG011430 LPS 84.6 5.8e-30 1 78 1.0 1 Immune modulation acyl carrier protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term