Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1857
  Reference Plasmid   1111525849663802_bin.17__k141_390665
  Reference Plasmid Size   2931
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0019001 EAOMANBP_00001 2339 3 Skin 0.60 protein_coding synonymous_variant LOW 387C>T Tyr129Tyr
M0019002 EAOMANBP_00001 62 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *717T>C None
M0019003 EAOMANBP_00001 72 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *707A>C None
M0019004 EAOMANBP_00001 106 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *673T>C None
M0019005 EAOMANBP_00001 107 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *672A>T None
M0019006 EAOMANBP_00001 132 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *647T>C None
M0019007 EAOMANBP_00001 150 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *629C>T None
M0019008 EAOMANBP_00001 151 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *628G>A None
M0019009 EAOMANBP_00001 160 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *619A>C None
M0019010 EAOMANBP_00001 161 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *618C>T None
M0019011 EAOMANBP_00001 199 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *580C>T None
M0019012 EAOMANBP_00001 211 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *568A>G None
M0019013 EAOMANBP_00001 258 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *521T>G None
M0019014 EAOMANBP_00001 292 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *487G>A None
M0019015 EAOMANBP_00001 304 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *475T>C None
M0019016 EAOMANBP_00001 318 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *461A>T None
M0019017 EAOMANBP_00001 339 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *440A>T None
M0019018 EAOMANBP_00001 340 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *439G>A None
M0019019 EAOMANBP_00001 346 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *433T>A None
M0019020 EAOMANBP_00001 364 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *415C>T None
M0019021 EAOMANBP_00001 405 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *374A>G None
M0019022 EAOMANBP_00001 410 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *369G>A None
M0019023 EAOMANBP_00001 539 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *240G>A None
M0019024 EAOMANBP_00001 558 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *221C>T None
M0019025 EAOMANBP_00001 565 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *214A>G None
M0019026 EAOMANBP_00001 584 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *195C>T None
M0019027 EAOMANBP_00001 585 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *194A>G None
M0019028 EAOMANBP_00001 591 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *188G>A None
M0019029 EAOMANBP_00001 594 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *185C>T None
M0019030 EAOMANBP_00001 661 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *118A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term