Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1868
  Reference Plasmid   1111525849664398_bin.8__k141_11378
  Reference Plasmid Size   6064
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0019090 OGCEGFLN_00001 251 4 Skin 0.44 protein_coding synonymous_variant LOW 1254C>T Asn418Asn
M0019091 OGCEGFLN_00001 791 4 Skin 0.44 protein_coding synonymous_variant LOW 714A>C Gly238Gly
M0019092 OGCEGFLN_00001 872 3 Skin 0.33 protein_coding synonymous_variant LOW 633T>C Gly211Gly
M0019093 OGCEGFLN_00001 873 5 Skin 0.56 protein_coding missense_variant MODERATE 632G>A Gly211Asp
M0019094 OGCEGFLN_00001 926 3 Skin 0.33 protein_coding synonymous_variant LOW 579C>T Asp193Asp
M0019095 OGCEGFLN_00001 1258 4 Skin 0.44 protein_coding synonymous_variant LOW 247C>T Leu83Leu
M0019096 OGCEGFLN_00001 1439 5 Skin 0.56 protein_coding synonymous_variant LOW 66A>G Gln22Gln
M0019097 OGCEGFLN_00001 1460 6 Skin 0.67 protein_coding synonymous_variant LOW 45C>A Ile15Ile
M0019098 OGCEGFLN_00002 1652 4 Skin 0.44 protein_coding synonymous_variant LOW 63G>A Glu21Glu
M0019099 OGCEGFLN_00001 2068 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -564T>A None
M0019100 OGCEGFLN_00001 2094 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -590G>A None
M0019101 OGCEGFLN_00001 2100 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -596T>A None
M0019102 OGCEGFLN_00003 2201 6 Skin 0.67 protein_coding missense_variant MODERATE 4A>G Ser2Gly
M0019103 OGCEGFLN_00003 2266 3 Skin 0.33 protein_coding missense_variant MODERATE 69C>G Asn23Lys
M0019104 OGCEGFLN_00003 2282 3 Skin 0.33 protein_coding missense_variant MODERATE 85A>G Ile29Val
M0019105 OGCEGFLN_00003 2323 4 Skin 0.44 protein_coding synonymous_variant LOW 126G>A Lys42Lys
M0019106 OGCEGFLN_00001 2355 9 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -851G>C None
M0019107 OGCEGFLN_00001 2421 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -917G>A None
M0019108 OGCEGFLN_00001 2452 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -948A>G None
M0019109 OGCEGFLN_00001 2499 9 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -995A>G None
M0019110 OGCEGFLN_00004 2552 3 Skin 0.33 protein_coding missense_variant MODERATE 976G>A Glu326Lys
M0019111 OGCEGFLN_00004 2586 3 Skin 0.33 protein_coding synonymous_variant LOW 942T>C Asp314Asp
M0019112 OGCEGFLN_00004 2610 5 Skin 0.56 protein_coding synonymous_variant LOW 918T>C Leu306Leu
M0019113 OGCEGFLN_00004 2619 3 Skin 0.33 protein_coding synonymous_variant LOW 909C>A Ile303Ile
M0019114 OGCEGFLN_00004 2625 5 Skin 0.56 protein_coding synonymous_variant LOW 903G>T Gly301Gly
M0019115 OGCEGFLN_00004 2648 3 Skin 0.33 protein_coding missense_variant MODERATE 880G>C Glu294Gln
M0019116 OGCEGFLN_00004 2688 3 Skin 0.33 protein_coding synonymous_variant LOW 840G>T Gly280Gly
M0019117 OGCEGFLN_00004 2706 5 Skin 0.56 protein_coding synonymous_variant LOW 822A>G Ala274Ala
M0019118 OGCEGFLN_00004 2712 3 Skin 0.33 protein_coding synonymous_variant LOW 816A>G Glu272Glu
M0019119 OGCEGFLN_00004 2724 5 Skin 0.56 protein_coding synonymous_variant LOW 804A>T Pro268Pro
M0019120 OGCEGFLN_00004 2736 3 Skin 0.33 protein_coding synonymous_variant LOW 792C>A Ala264Ala
M0019121 OGCEGFLN_00004 2793 3 Skin 0.33 protein_coding synonymous_variant LOW 735A>G Val245Val
M0019122 OGCEGFLN_00004 2807 3 Skin 0.33 protein_coding missense_variant MODERATE 721T>G Ser241Ala
M0019123 OGCEGFLN_00004 2849 3 Skin 0.33 protein_coding missense_variant MODERATE 679T>G Ser227Ala
M0019124 OGCEGFLN_00004 2895 3 Skin 0.33 protein_coding synonymous_variant LOW 633A>G Glu211Glu
M0019125 OGCEGFLN_00004 2979 3 Skin 0.33 protein_coding synonymous_variant LOW 549A>G Leu183Leu
M0019126 OGCEGFLN_00004 2994 8 Skin 0.89 protein_coding synonymous_variant LOW 534C>T Ala178Ala
M0019127 OGCEGFLN_00004 3039 3 Skin 0.33 protein_coding synonymous_variant LOW 489C>A Val163Val
M0019128 OGCEGFLN_00004 3269 4 Skin 0.44 protein_coding synonymous_variant LOW 259C>T Leu87Leu
M0019129 OGCEGFLN_00001 476 3 Skin 0.33 protein_coding synonymous_variant LOW 1029C>A Gly343Gly
M0019130 OGCEGFLN_00001 868 3 Skin 0.33 protein_coding missense_variant MODERATE 637G>C Glu213Gln
M0019131 OGCEGFLN_00001 1051 3 Skin 0.33 protein_coding missense_variant MODERATE 454G>A Asp152Asn
M0019132 OGCEGFLN_00001 1557 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -53A>T None
M0019133 OGCEGFLN_00001 2045 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -541G>C None
M0019134 OGCEGFLN_00001 2046 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -542A>T None
M0019135 OGCEGFLN_00001 2052 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -548G>A None
M0019136 OGCEGFLN_00001 2075 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -571T>C None
M0019137 OGCEGFLN_00001 2079 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -575C>T None
M0019138 OGCEGFLN_00001 2080 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -576A>G None
M0019139 OGCEGFLN_00001 2102 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -598T>C None
M0019140 OGCEGFLN_00001 2116 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -612C>T None
M0019141 OGCEGFLN_00001 2154 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -650T>A None
M0019142 OGCEGFLN_00001 3614 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -2110C>T None
M0019143 OGCEGFLN_00001 3679 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -2175T>G None
M0019144 OGCEGFLN_00005 4211 3 Skin 0.33 protein_coding missense_variant MODERATE 442A>G Ile148Val
M0019145 OGCEGFLN_00001 1255 3 Skin 0.33 protein_coding missense_variant MODERATE 250G>A Val84Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term