Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1877
  Reference Plasmid   1111525849667770_bin.36__k141_126212
  Reference Plasmid Size   2707
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0019312 DLDDOCCG_00001 155 3 Skin 1.00 protein_coding synonymous_variant LOW 132C>T Arg44Arg
M0019313 DLDDOCCG_00001 266 3 Skin 1.00 protein_coding synonymous_variant LOW 243C>G Ser81Ser
M0019314 DLDDOCCG_00001 267 3 Skin 1.00 protein_coding missense_variant MODERATE 244A>G Lys82Glu
M0019315 DLDDOCCG_00001 268 3 Skin 1.00 protein_coding missense_variant MODERATE 245A>T Lys82Met
M0019316 DLDDOCCG_00001 461 3 Skin 1.00 protein_coding synonymous_variant LOW 438C>T Gly146Gly
M0019317 DLDDOCCG_00001 494 3 Skin 1.00 protein_coding synonymous_variant LOW 471C>T His157His
M0019318 DLDDOCCG_00001 503 3 Skin 1.00 protein_coding synonymous_variant LOW 480C>T Ala160Ala
M0019319 DLDDOCCG_00001 518 3 Skin 1.00 protein_coding synonymous_variant LOW 495C>T Gly165Gly
M0019320 DLDDOCCG_00001 520 3 Skin 1.00 protein_coding missense_variant MODERATE 497C>G Thr166Ser
M0019321 DLDDOCCG_00001 524 3 Skin 1.00 protein_coding synonymous_variant LOW 501G>A Arg167Arg
M0019322 DLDDOCCG_00001 599 3 Skin 1.00 protein_coding synonymous_variant LOW 576C>T Arg192Arg
M0019323 DLDDOCCG_00002 983 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -47C>G None
M0019324 DLDDOCCG_00004 2006 3 Skin 1.00 protein_coding synonymous_variant LOW 93T>G Gly31Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term