Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1880
  Reference Plasmid   1111525849667897_bin.20__k141_260047
  Reference Plasmid Size   16848
  Reference Plasmid GC Content   0.55
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0019338 AIHEOFJB_00004 3544 9 Skin 0.35 protein_coding missense_variant MODERATE 269C>T Ala90Val
M0019339 AIHEOFJB_00005 3849 4 Skin 0.15 protein_coding missense_variant MODERATE 286G>C Val96Leu
M0019340 AIHEOFJB_00005 3919 4 Skin 0.15 protein_coding missense_variant MODERATE 216G>C Arg72Ser
M0019341 AIHEOFJB_00005 3925 4 Skin 0.15 protein_coding synonymous_variant LOW 210T>C Gly70Gly
M0019342 AIHEOFJB_00005 4111 3 Skin 0.12 protein_coding synonymous_variant LOW 24C>A Ala8Ala
M0019343 AIHEOFJB_00006 4426 3 Skin 0.12 protein_coding synonymous_variant LOW 495C>T Asp165Asp
M0019344 AIHEOFJB_00006 4432 3 Skin 0.12 protein_coding synonymous_variant LOW 489G>A Ala163Ala
M0019345 AIHEOFJB_00006 4435 3 Skin 0.12 protein_coding synonymous_variant LOW 486T>C Ser162Ser
M0019346 AIHEOFJB_00006 4441 3 Skin 0.12 protein_coding synonymous_variant LOW 480T>C Ser160Ser
M0019347 AIHEOFJB_00006 4466 3 Skin 0.12 protein_coding missense_variant MODERATE 455G>A Gly152Asp
M0019348 AIHEOFJB_00006 4495 3 Skin 0.12 protein_coding synonymous_variant LOW 426G>A Leu142Leu
M0019349 AIHEOFJB_00006 4539 4 Skin 0.15 protein_coding missense_variant MODERATE 382C>T Pro128Ser
M0019350 AIHEOFJB_00006 4741 4 Skin 0.15 protein_coding synonymous_variant LOW 180G>A Leu60Leu
M0019351 AIHEOFJB_00006 4765 4 Skin 0.15 protein_coding synonymous_variant LOW 156G>A Leu52Leu
M0019352 AIHEOFJB_00003 2473 5 Skin 0.19 protein_coding synonymous_variant LOW 891C>T Gly297Gly
M0019353 AIHEOFJB_00006 4343 9 Skin 0.35 protein_coding missense_variant MODERATE 578G>A Arg193Lys
M0019354 AIHEOFJB_00001 277 3 Skin 0.12 protein_coding synonymous_variant LOW 318T>C Phe106Phe
M0019355 AIHEOFJB_00002 904 5 Skin 0.19 protein_coding synonymous_variant LOW 175T>C Leu59Leu
M0019356 AIHEOFJB_00020 16027 6 Skin 0.23 protein_coding synonymous_variant LOW 666G>A Val222Val
M0019357 AIHEOFJB_00020 16036 6 Skin 0.23 protein_coding synonymous_variant LOW 657G>C Gly219Gly
M0019358 AIHEOFJB_00001 469 5 Skin 0.19 protein_coding synonymous_variant LOW 126C>A Ala42Ala
M0019359 AIHEOFJB_00020 16246 3 Skin 0.12 protein_coding synonymous_variant LOW 447A>G Gln149Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term