Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1898
  Reference Plasmid   1111525849668081_bin.18__k141_326172
  Reference Plasmid Size   7861
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0019532 CGOCGFCJ_00004 5437 10 Skin 0.50 protein_coding missense_variant MODERATE 95G>A Arg32His
M0019533 CGOCGFCJ_00004 5457 10 Skin 0.50 protein_coding synonymous_variant LOW 75C>G Gly25Gly
M0019534 CGOCGFCJ_00004 5463 12 Skin 0.60 protein_coding synonymous_variant LOW 69G>A Glu23Glu
M0019535 CGOCGFCJ_00005 5897 12 Skin 0.60 protein_coding synonymous_variant LOW 1287G>A Ala429Ala
M0019536 CGOCGFCJ_00005 5927 12 Skin 0.60 protein_coding synonymous_variant LOW 1257G>T Ser419Ser
M0019537 CGOCGFCJ_00005 5930 12 Skin 0.60 protein_coding synonymous_variant LOW 1254G>A Val418Val
M0019538 CGOCGFCJ_00005 6506 9 Skin 0.45 protein_coding synonymous_variant LOW 678G>A Gly226Gly
M0019539 CGOCGFCJ_00005 6533 10 Skin 0.50 protein_coding synonymous_variant LOW 651C>G Gly217Gly
M0019540 CGOCGFCJ_00005 6560 10 Skin 0.50 protein_coding synonymous_variant LOW 624C>G Ala208Ala
M0019541 CGOCGFCJ_00005 6725 12 Skin 0.60 protein_coding synonymous_variant LOW 459C>G Ala153Ala
M0019542 CGOCGFCJ_00005 6731 12 Skin 0.60 protein_coding synonymous_variant LOW 453C>G Gly151Gly
M0019543 CGOCGFCJ_00005 6737 12 Skin 0.60 protein_coding synonymous_variant LOW 447A>G Glu149Glu
M0019544 CGOCGFCJ_00005 6740 12 Skin 0.60 protein_coding synonymous_variant LOW 444T>C Val148Val
M0019545 CGOCGFCJ_00005 6743 12 Skin 0.60 protein_coding synonymous_variant LOW 441C>G Leu147Leu
M0019546 CGOCGFCJ_00005 6752 11 Skin 0.55 protein_coding synonymous_variant LOW 432A>G Lys144Lys
M0019547 CGOCGFCJ_00005 6872 10 Skin 0.50 protein_coding synonymous_variant LOW 312C>T Asp104Asp
M0019548 CGOCGFCJ_00006 7697 12 Skin 0.60 protein_coding synonymous_variant LOW 120C>T Gly40Gly
M0019549 CGOCGFCJ_00006 7703 12 Skin 0.60 protein_coding synonymous_variant LOW 114G>C Gly38Gly
M0019550 CGOCGFCJ_00006 7732 12 Skin 0.60 protein_coding missense_variant MODERATE 85G>C Glu29Gln
M0019551 CGOCGFCJ_00006 7778 12 Skin 0.60 protein_coding synonymous_variant LOW 39C>T Ile13Ile
M0019552 CGOCGFCJ_00003 7817 12 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4514G>C None
M0019553 CGOCGFCJ_00002 1228 8 Skin 0.40 protein_coding synonymous_variant LOW 897G>A Gly299Gly
M0019554 CGOCGFCJ_00003 2430 8 Skin 0.40 protein_coding synonymous_variant LOW 874C>T Leu292Leu
M0019555 CGOCGFCJ_00003 2950 3 Skin 0.15 protein_coding synonymous_variant LOW 354C>T His118His
M0019556 CGOCGFCJ_00003 2971 3 Skin 0.15 protein_coding synonymous_variant LOW 333A>G Gly111Gly
M0019557 CGOCGFCJ_00004 3609 3 Skin 0.15 protein_coding synonymous_variant LOW 1923G>C Thr641Thr
M0019558 CGOCGFCJ_00004 4662 3 Skin 0.15 protein_coding synonymous_variant LOW 870C>T Asp290Asp
M0019559 CGOCGFCJ_00004 4668 3 Skin 0.15 protein_coding synonymous_variant LOW 864C>T Asp288Asp
M0019560 CGOCGFCJ_00004 5217 6 Skin 0.30 protein_coding synonymous_variant LOW 315A>G Ala105Ala
M0019561 CGOCGFCJ_00005 6269 4 Skin 0.20 protein_coding synonymous_variant LOW 915G>C Thr305Thr
M0019562 CGOCGFCJ_00005 6275 3 Skin 0.15 protein_coding synonymous_variant LOW 909C>G Pro303Pro
M0019563 CGOCGFCJ_00004 3948 4 Skin 0.20 protein_coding synonymous_variant LOW 1584C>G Val528Val
M0019564 CGOCGFCJ_00004 3950 4 Skin 0.20 protein_coding missense_variant MODERATE 1582G>C Val528Leu
M0019565 CGOCGFCJ_00004 3960 4 Skin 0.20 protein_coding synonymous_variant LOW 1572G>A Gly524Gly
M0019566 CGOCGFCJ_00004 4125 4 Skin 0.20 protein_coding synonymous_variant LOW 1407A>G Glu469Glu
M0019567 CGOCGFCJ_00004 3858 3 Skin 0.15 protein_coding synonymous_variant LOW 1674C>T Gly558Gly
M0019568 CGOCGFCJ_00004 3885 3 Skin 0.15 protein_coding synonymous_variant LOW 1647G>T Ser549Ser
M0019569 CGOCGFCJ_00004 3903 3 Skin 0.15 protein_coding synonymous_variant LOW 1629C>G Val543Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CGOCGFCJ_00004 ARJ70733.1|GT2 72.7 0 62 743 0.9179 0.9827





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term