Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1909
  Reference Plasmid   1111525849668257_bin.2__k141_253266
  Reference Plasmid Size   34303
  Reference Plasmid GC Content   0.72
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0019697 KFMNJEPA_00023 28759 3 Skin 0.19 protein_coding synonymous_variant LOW 744G>C Ala248Ala
M0019698 KFMNJEPA_00023 28762 3 Skin 0.19 protein_coding synonymous_variant LOW 741G>C Ala247Ala
M0019699 KFMNJEPA_00023 29487 5 Skin 0.31 protein_coding missense_variant MODERATE 16C>A Pro6Thr
M0019700 KFMNJEPA_00024 30108 3 Skin 0.19 protein_coding synonymous_variant LOW 180C>T Ser60Ser
M0019701 KFMNJEPA_00024 30140 4 Skin 0.25 protein_coding synonymous_variant LOW 148T>C Leu50Leu
M0019702 KFMNJEPA_00024 30141 4 Skin 0.25 protein_coding synonymous_variant LOW 147T>C Val49Val
M0019703 KFMNJEPA_00024 30227 3 Skin 0.19 protein_coding missense_variant MODERATE 61G>A Ala21Thr
M0019704 KFMNJEPA_00024 30234 3 Skin 0.19 protein_coding synonymous_variant LOW 54T>G Gly18Gly
M0019705 KFMNJEPA_00025 30395 4 Skin 0.25 protein_coding synonymous_variant LOW 636A>G Gly212Gly
M0019706 KFMNJEPA_00025 30407 4 Skin 0.25 protein_coding synonymous_variant LOW 624C>T Arg208Arg
M0019707 KFMNJEPA_00025 30894 3 Skin 0.19 protein_coding missense_variant MODERATE 137T>C Val46Ala
M0019708 KFMNJEPA_00025 30932 3 Skin 0.19 protein_coding synonymous_variant LOW 99A>G Ala33Ala
M0019709 KFMNJEPA_00025 30952 3 Skin 0.19 protein_coding missense_variant MODERATE 79A>G Thr27Ala
M0019710 KFMNJEPA_00026 31665 4 Skin 0.25 protein_coding synonymous_variant LOW 420G>A Leu140Leu
M0019711 KFMNJEPA_00026 32080 5 Skin 0.31 protein_coding missense_variant MODERATE 5A>G Asn2Ser
M0019712 KFMNJEPA_00027 32420 4 Skin 0.25 protein_coding synonymous_variant LOW 537T>C Leu179Leu
M0019713 KFMNJEPA_00028 33502 4 Skin 0.25 protein_coding synonymous_variant LOW 462C>G Leu154Leu
M0019714 KFMNJEPA_00028 33745 3 Skin 0.19 protein_coding synonymous_variant LOW 219A>G Gly73Gly
M0019715 KFMNJEPA_00020 26269 4 Skin 0.25 protein_coding synonymous_variant LOW 681T>C Leu227Leu
M0019716 KFMNJEPA_00026 31458 3 Skin 0.19 protein_coding synonymous_variant LOW 627C>T Arg209Arg
M0019717 KFMNJEPA_00026 32010 3 Skin 0.19 protein_coding synonymous_variant LOW 75C>G Ala25Ala
M0019718 KFMNJEPA_00028 32965 3 Skin 0.19 protein_coding synonymous_variant LOW 999C>G Ala333Ala
M0019719 KFMNJEPA_00028 33811 3 Skin 0.19 protein_coding synonymous_variant LOW 153C>T Pro51Pro
M0019720 KFMNJEPA_00028 33826 3 Skin 0.19 protein_coding synonymous_variant LOW 138G>A Leu46Leu
M0019721 KFMNJEPA_00009 12839 3 Skin 0.19 protein_coding synonymous_variant LOW 1464T>C Gly488Gly
M0019722 KFMNJEPA_00010 13477 3 Skin 0.19 protein_coding synonymous_variant LOW 543T>C Gly181Gly
M0019723 KFMNJEPA_00003 3060 3 Skin 0.19 protein_coding synonymous_variant LOW 951C>G Gly317Gly
M0019724 KFMNJEPA_00003 3309 3 Skin 0.19 protein_coding synonymous_variant LOW 702C>T Ile234Ile
M0019725 KFMNJEPA_00004 5425 3 Skin 0.19 protein_coding synonymous_variant LOW 105T>C Asp35Asp
M0019726 KFMNJEPA_00005 5953 3 Skin 0.19 protein_coding missense_variant MODERATE 727A>G Thr243Ala
M0019727 KFMNJEPA_00006 6883 3 Skin 0.19 protein_coding synonymous_variant LOW 1119T>C Thr373Thr
M0019728 KFMNJEPA_00007 8381 3 Skin 0.19 protein_coding synonymous_variant LOW 652C>T Leu218Leu
M0019729 KFMNJEPA_00007 8457 3 Skin 0.19 protein_coding synonymous_variant LOW 576G>A Glu192Glu
M0019730 KFMNJEPA_00008 9452 3 Skin 0.19 protein_coding synonymous_variant LOW 87C>T Pro29Pro
M0019731 KFMNJEPA_00008 9458 3 Skin 0.19 protein_coding synonymous_variant LOW 93C>T Pro31Pro
M0019732 KFMNJEPA_00008 9460 4 Skin 0.25 protein_coding missense_variant MODERATE 95G>A Gly32Asp
M0019733 KFMNJEPA_00008 9665 3 Skin 0.19 protein_coding synonymous_variant LOW 300T>C Arg100Arg
M0019734 KFMNJEPA_00008 10808 3 Skin 0.19 protein_coding synonymous_variant LOW 1443G>A Gly481Gly
M0019735 KFMNJEPA_00008 11021 3 Skin 0.19 protein_coding synonymous_variant LOW 1656C>T Tyr552Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term