Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1923
  Reference Plasmid   1111525849668516_bin.6__k141_180991
  Reference Plasmid Size   7778
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0019786 COANKKDB_00006 5657 3 Skin 1.00 protein_coding missense_variant MODERATE 208C>T Leu70Phe
M0019787 COANKKDB_00006 6057 3 Skin 1.00 protein_coding missense_variant MODERATE 608T>G Phe203Cys
M0019788 COANKKDB_00006 6107 3 Skin 1.00 protein_coding missense_variant MODERATE 658G>T Ala220Ser
M0019789 COANKKDB_00006 6157 3 Skin 1.00 protein_coding synonymous_variant LOW 708G>A Glu236Glu
M0019790 COANKKDB_00006 6308 3 Skin 1.00 protein_coding missense_variant MODERATE 859C>G Leu287Val
M0019791 COANKKDB_00006 6365 3 Skin 1.00 protein_coding missense_variant MODERATE 916T>G Phe306Val
M0019792 COANKKDB_00006 6376 3 Skin 1.00 protein_coding synonymous_variant LOW 927C>T Phe309Phe
M0019793 COANKKDB_00006 6382 3 Skin 1.00 protein_coding synonymous_variant LOW 933T>C Gly311Gly
M0019794 COANKKDB_00006 6388 3 Skin 1.00 protein_coding synonymous_variant LOW 939A>G Glu313Glu
M0019795 COANKKDB_00006 6390 3 Skin 1.00 protein_coding missense_variant MODERATE 941A>G His314Arg
M0019796 COANKKDB_00006 6473 3 Skin 1.00 protein_coding missense_variant MODERATE 1024A>G Thr342Ala
M0019797 COANKKDB_00006 6474 3 Skin 1.00 protein_coding missense_variant MODERATE 1025C>T Thr342Ile
M0019798 COANKKDB_00007 6651 3 Skin 1.00 protein_coding synonymous_variant LOW 222T>C Ile74Ile
M0019799 COANKKDB_00007 6849 3 Skin 1.00 protein_coding synonymous_variant LOW 24G>C Ala8Ala
M0019800 COANKKDB_00007 6855 3 Skin 1.00 protein_coding synonymous_variant LOW 18T>C Ala6Ala
M0019801 COANKKDB_00008 6947 3 Skin 1.00 protein_coding missense_variant MODERATE 415T>G Ser139Ala
M0019802 COANKKDB_00008 7029 3 Skin 1.00 protein_coding synonymous_variant LOW 333A>C Thr111Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
COANKKDB_00003 PHI:123732 oxyR (Aave_0594) 79.1 4.4e-140 1 317 1.0000 1.0000 eudicots bacterial fruit blotch transcriptional regulator reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term