Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1928
  Reference Plasmid   1111525849668582_bin.4__k141_472742
  Reference Plasmid Size   23153
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0020086 CILBBFKA_00009 10586 5 Skin 0.31 protein_coding missense_variant MODERATE 952G>A Ala318Thr
M0020087 CILBBFKA_00012 12851 11 Skin 0.69 protein_coding missense_variant MODERATE 1099T>C Tyr367His
M0020088 CILBBFKA_00013 14941 11 Skin 0.69 protein_coding missense_variant MODERATE 790C>A Gln264Lys
M0020089 CILBBFKA_00014 15775 3 Skin 0.19 protein_coding synonymous_variant LOW 198G>C Pro66Pro
M0020090 CILBBFKA_00014 16048 8 Skin 0.50 protein_coding synonymous_variant LOW 471A>G Leu157Leu
M0020091 CILBBFKA_00012 13480 4 Skin 0.25 protein_coding missense_variant MODERATE 470A>T Gln157Leu
M0020092 CILBBFKA_00012 13511 3 Skin 0.19 protein_coding synonymous_variant LOW 439T>C Leu147Leu
M0020093 CILBBFKA_00012 13515 3 Skin 0.19 protein_coding synonymous_variant LOW 435G>C Val145Val
M0020094 CILBBFKA_00012 13521 3 Skin 0.19 protein_coding synonymous_variant LOW 429C>G Arg143Arg
M0020095 CILBBFKA_00013 14641 3 Skin 0.19 protein_coding synonymous_variant LOW 490T>C Leu164Leu
M0020096 CILBBFKA_00013 14647 3 Skin 0.19 protein_coding missense_variant MODERATE 496A>G Asn166Asp
M0020097 CILBBFKA_00013 14652 3 Skin 0.19 protein_coding synonymous_variant LOW 501C>G Leu167Leu
M0020098 CILBBFKA_00013 14658 3 Skin 0.19 protein_coding synonymous_variant LOW 507A>G Gln169Gln
M0020099 CILBBFKA_00012 13370 3 Skin 0.19 protein_coding missense_variant MODERATE 580A>C Ile194Leu
M0020100 CILBBFKA_00012 13407 3 Skin 0.19 protein_coding synonymous_variant LOW 543T>C Leu181Leu
M0020101 CILBBFKA_00012 13434 3 Skin 0.19 protein_coding synonymous_variant LOW 516T>G Gly172Gly
M0020102 CILBBFKA_00012 13674 3 Skin 0.19 protein_coding synonymous_variant LOW 276T>C Pro92Pro
M0020103 CILBBFKA_00012 13698 3 Skin 0.19 protein_coding synonymous_variant LOW 252C>T Leu84Leu
M0020104 CILBBFKA_00012 13710 3 Skin 0.19 protein_coding synonymous_variant LOW 240G>C Gly80Gly
M0020105 CILBBFKA_00012 13713 3 Skin 0.19 protein_coding synonymous_variant LOW 237C>G Ala79Ala
M0020106 CILBBFKA_00012 13776 3 Skin 0.19 protein_coding synonymous_variant LOW 174G>C Ala58Ala
M0020107 CILBBFKA_00011 14038 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -1652C>G None
M0020108 CILBBFKA_00011 14070 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -1684A>G None
M0020109 CILBBFKA_00011 14101 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -1715G>A None
M0020110 CILBBFKA_00011 14114 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -1728G>C None
M0020111 CILBBFKA_00013 14262 3 Skin 0.19 protein_coding synonymous_variant LOW 111T>C Pro37Pro
M0020112 CILBBFKA_00006 6323 3 Skin 0.19 protein_coding missense_variant MODERATE 1280C>T Pro427Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CILBBFKA_00012 QQO45852.1|CE4 89.3 0 1 466 0.9979 0.9979





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term