Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1935
  Reference Plasmid   1111525849668850_bin.11__k141_66246
  Reference Plasmid Size   4410
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0020202 ANLEPENM_00001 849 3 Skin 0.75 protein_coding synonymous_variant LOW 271T>C Leu91Leu
M0020203 ANLEPENM_00001 862 3 Skin 0.75 protein_coding synonymous_variant LOW 258T>C Asp86Asp
M0020204 ANLEPENM_00001 1277 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -158G>A None
M0020205 ANLEPENM_00003 1966 4 Skin 1.00 protein_coding synonymous_variant LOW 354C>T Gly118Gly
M0020206 ANLEPENM_00005 3675 3 Skin 0.75 protein_coding synonymous_variant LOW 1011T>C Asp337Asp
M0020207 ANLEPENM_00005 3679 3 Skin 0.75 protein_coding missense_variant MODERATE 1015C>G Pro339Ala
M0020208 ANLEPENM_00005 3681 3 Skin 0.75 protein_coding synonymous_variant LOW 1017G>A Pro339Pro
M0020209 ANLEPENM_00005 3698 3 Skin 0.75 protein_coding missense_variant MODERATE 1034C>A Ala345Asp
M0020210 ANLEPENM_00005 3730 3 Skin 0.75 protein_coding synonymous_variant LOW 1066T>C Leu356Leu
M0020211 ANLEPENM_00005 3891 3 Skin 0.75 protein_coding synonymous_variant LOW 1227T>A Val409Val
M0020212 ANLEPENM_00005 3931 3 Skin 0.75 protein_coding missense_variant MODERATE 1267C>A His423Asn
M0020213 ANLEPENM_00005 3936 3 Skin 0.75 protein_coding synonymous_variant LOW 1272G>A Gly424Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
ANLEPENM_00001 Copper (Cu) 83.6 2.8e-105 1 226 0.9956 0.9784 experiment
ANLEPENM_00001 Copper (Cu) 99.6 1.1e-123 1 227 1.0000 1.0000 prediction
ANLEPENM_00005 Copper (Cu), Silver (Ag) 75.9 1e-222 1 485 1.0082 0.8232 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
ANLEPENM_00005 9.B.62.1.5 70.1 6.2e-202 1 485 1.0000 1.5773 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.62 The Copper Resistance (CopD) Family