Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1936
  Reference Plasmid   1111525849668850_bin.12__k141_144841
  Reference Plasmid Size   9646
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0020214 DIBJBJNB_00003 2558 4 Skin 0.36 protein_coding synonymous_variant LOW 840T>C Ala280Ala
M0020215 DIBJBJNB_00003 2633 4 Skin 0.36 protein_coding synonymous_variant LOW 915A>G Ala305Ala
M0020216 DIBJBJNB_00004 3225 3 Skin 0.27 protein_coding synonymous_variant LOW 369A>C Ile123Ile
M0020217 DIBJBJNB_00004 3258 4 Skin 0.36 protein_coding synonymous_variant LOW 402T>G Leu134Leu
M0020218 DIBJBJNB_00004 3264 4 Skin 0.36 protein_coding missense_variant MODERATE 408G>C Lys136Asn
M0020219 DIBJBJNB_00004 3300 3 Skin 0.27 protein_coding synonymous_variant LOW 444C>G Pro148Pro
M0020220 DIBJBJNB_00004 3949 3 Skin 0.27 protein_coding missense_variant MODERATE 1093A>G Thr365Ala
M0020221 DIBJBJNB_00004 3981 4 Skin 0.36 protein_coding synonymous_variant LOW 1125T>C Pro375Pro
M0020222 DIBJBJNB_00004 3997 4 Skin 0.36 protein_coding missense_variant MODERATE 1141C>G Gln381Glu
M0020223 DIBJBJNB_00002 4008 4 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -2468T>G None
M0020224 DIBJBJNB_00005 4277 3 Skin 0.27 protein_coding synonymous_variant LOW 213T>C Pro71Pro
M0020225 DIBJBJNB_00005 4439 3 Skin 0.27 protein_coding synonymous_variant LOW 375C>G Val125Val
M0020226 DIBJBJNB_00002 4485 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -2945T>C None
M0020227 DIBJBJNB_00007 4900 5 Skin 0.45 protein_coding missense_variant MODERATE 121A>G Arg41Gly
M0020228 DIBJBJNB_00007 4944 5 Skin 0.45 protein_coding synonymous_variant LOW 165A>C Ile55Ile
M0020229 DIBJBJNB_00008 4980 5 Skin 0.45 protein_coding missense_variant MODERATE 1G>A Val1Met
M0020230 DIBJBJNB_00008 5073 3 Skin 0.27 protein_coding missense_variant MODERATE 94A>C Asn32His
M0020231 DIBJBJNB_00008 5097 3 Skin 0.27 protein_coding missense_variant MODERATE 118T>G Ser40Ala
M0020232 DIBJBJNB_00008 5115 3 Skin 0.27 protein_coding missense_variant MODERATE 136G>A Ala46Thr
M0020233 DIBJBJNB_00008 5224 5 Skin 0.45 protein_coding missense_variant MODERATE 245C>A Pro82Gln
M0020234 DIBJBJNB_00008 5278 6 Skin 0.55 protein_coding missense_variant MODERATE 299A>G Gln100Arg
M0020235 DIBJBJNB_00008 5519 4 Skin 0.36 protein_coding synonymous_variant LOW 540T>C Gly180Gly
M0020236 DIBJBJNB_00008 5547 4 Skin 0.36 protein_coding missense_variant MODERATE 568A>G Thr190Ala
M0020237 DIBJBJNB_00008 5630 5 Skin 0.45 protein_coding synonymous_variant LOW 651T>C Thr217Thr
M0020238 DIBJBJNB_00008 6041 4 Skin 0.36 protein_coding synonymous_variant LOW 1062G>C Arg354Arg
M0020239 DIBJBJNB_00008 6065 3 Skin 0.27 protein_coding synonymous_variant LOW 1086C>T Ala362Ala
M0020240 DIBJBJNB_00008 6119 3 Skin 0.27 protein_coding synonymous_variant LOW 1140T>C Ala380Ala
M0020241 DIBJBJNB_00009 6422 3 Skin 0.27 protein_coding missense_variant MODERATE 173T>C Val58Ala
M0020242 DIBJBJNB_00006 6545 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -1829C>A None
M0020243 DIBJBJNB_00011 7008 3 Skin 0.27 protein_coding missense_variant MODERATE 11T>C Leu4Pro
M0020244 DIBJBJNB_00011 7088 3 Skin 0.27 protein_coding missense_variant MODERATE 91T>C Phe31Leu
M0020245 DIBJBJNB_00011 7116 3 Skin 0.27 protein_coding missense_variant MODERATE 119C>G Ala40Gly
M0020246 DIBJBJNB_00011 7324 3 Skin 0.27 protein_coding synonymous_variant LOW 327C>A Ala109Ala
M0020247 DIBJBJNB_00011 7357 3 Skin 0.27 protein_coding synonymous_variant LOW 360A>G Ala120Ala
M0020248 DIBJBJNB_00002 1151 3 Skin 0.27 protein_coding synonymous_variant LOW 390G>C Gly130Gly
M0020249 DIBJBJNB_00010 6773 3 Skin 0.27 protein_coding synonymous_variant LOW 105C>G Thr35Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term