Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1946
  Reference Plasmid   1111525849669879_bin.31__k141_96896
  Reference Plasmid Size   2716
  Reference Plasmid GC Content   0.58
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0020526 LGPLGOGE_00001 142 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *859G>A None
M0020527 LGPLGOGE_00001 164 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *837G>A None
M0020528 LGPLGOGE_00001 274 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *727G>C None
M0020529 LGPLGOGE_00001 326 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *675G>A None
M0020530 LGPLGOGE_00001 331 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *670T>C None
M0020531 LGPLGOGE_00001 356 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *645T>A None
M0020532 LGPLGOGE_00001 373 4 Skin 0.27 protein_coding downstream_gene_variant MODIFIER *628T>C None
M0020533 LGPLGOGE_00001 410 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *591G>A None
M0020534 LGPLGOGE_00001 437 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *564C>T None
M0020535 LGPLGOGE_00001 441 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *560A>G None
M0020536 LGPLGOGE_00001 443 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *558A>C None
M0020537 LGPLGOGE_00001 448 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *553T>G None
M0020538 LGPLGOGE_00001 479 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *522C>T None
M0020539 LGPLGOGE_00001 491 9 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *510C>T None
M0020540 LGPLGOGE_00001 500 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *501C>G None
M0020541 LGPLGOGE_00001 506 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *495C>T None
M0020542 LGPLGOGE_00001 507 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *494G>A None
M0020543 LGPLGOGE_00001 524 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *477A>G None
M0020544 LGPLGOGE_00001 539 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *462T>A None
M0020545 LGPLGOGE_00001 540 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *461C>T None
M0020546 LGPLGOGE_00001 543 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *458G>C None
M0020547 LGPLGOGE_00001 548 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *453A>C None
M0020548 LGPLGOGE_00001 562 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *439C>G None
M0020549 LGPLGOGE_00001 569 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *432T>C None
M0020550 LGPLGOGE_00001 571 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *430G>A None
M0020551 LGPLGOGE_00001 596 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *405C>T None
M0020552 LGPLGOGE_00001 598 9 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *403A>G None
M0020553 LGPLGOGE_00001 640 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *361G>A None
M0020554 LGPLGOGE_00001 657 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *344A>T None
M0020555 LGPLGOGE_00001 658 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *343C>T None
M0020556 LGPLGOGE_00001 662 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *339A>G None
M0020557 LGPLGOGE_00001 695 8 Skin 0.53 protein_coding downstream_gene_variant MODIFIER *306T>C None
M0020558 LGPLGOGE_00001 806 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *195A>G None
M0020559 LGPLGOGE_00001 815 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *186G>A None
M0020560 LGPLGOGE_00001 840 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *161A>G None
M0020561 LGPLGOGE_00001 841 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *160A>G None
M0020562 LGPLGOGE_00001 860 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *141C>G None
M0020563 LGPLGOGE_00001 874 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *127T>A None
M0020564 LGPLGOGE_00001 881 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *120T>G None
M0020565 LGPLGOGE_00001 907 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *94A>G None
M0020566 LGPLGOGE_00001 916 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *85G>T None
M0020567 LGPLGOGE_00001 919 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *82T>C None
M0020568 LGPLGOGE_00001 926 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *75A>G None
M0020569 LGPLGOGE_00001 928 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *73A>G None
M0020570 LGPLGOGE_00001 976 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *25C>T None
M0020571 LGPLGOGE_00001 978 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *23A>G None
M0020572 LGPLGOGE_00001 1091 7 Skin 0.47 protein_coding synonymous_variant LOW 600T>A Val200Val
M0020573 LGPLGOGE_00001 1100 7 Skin 0.47 protein_coding synonymous_variant LOW 591T>C Ser197Ser
M0020574 LGPLGOGE_00001 1112 7 Skin 0.47 protein_coding synonymous_variant LOW 579T>G Pro193Pro
M0020575 LGPLGOGE_00001 1118 7 Skin 0.47 protein_coding synonymous_variant LOW 573G>A Lys191Lys
M0020576 LGPLGOGE_00001 1157 7 Skin 0.47 protein_coding synonymous_variant LOW 534A>G Val178Val
M0020577 LGPLGOGE_00001 1226 5 Skin 0.33 protein_coding synonymous_variant LOW 465T>C Arg155Arg
M0020578 LGPLGOGE_00001 1259 5 Skin 0.33 protein_coding synonymous_variant LOW 432A>G Lys144Lys
M0020579 LGPLGOGE_00001 1283 5 Skin 0.33 protein_coding synonymous_variant LOW 408C>T Ala136Ala
M0020580 LGPLGOGE_00001 1286 5 Skin 0.33 protein_coding synonymous_variant LOW 405T>C His135His
M0020581 LGPLGOGE_00001 1298 5 Skin 0.33 protein_coding synonymous_variant LOW 393T>A Gly131Gly
M0020582 LGPLGOGE_00001 1330 5 Skin 0.33 protein_coding synonymous_variant LOW 361T>C Leu121Leu
M0020583 LGPLGOGE_00001 1359 5 Skin 0.33 protein_coding missense_variant MODERATE 332C>T Ala111Val
M0020584 LGPLGOGE_00001 1463 5 Skin 0.33 protein_coding synonymous_variant LOW 228G>A Gln76Gln
M0020585 LGPLGOGE_00001 1469 5 Skin 0.33 protein_coding synonymous_variant LOW 222C>T Asp74Asp
M0020586 LGPLGOGE_00001 1546 3 Skin 0.20 protein_coding missense_variant MODERATE 145G>A Gly49Ser
M0020587 LGPLGOGE_00001 1548 4 Skin 0.27 protein_coding missense_variant MODERATE 143G>T Arg48Leu
M0020588 LGPLGOGE_00001 1549 4 Skin 0.27 protein_coding missense_variant MODERATE 142C>T Arg48Trp
M0020589 LGPLGOGE_00001 1569 4 Skin 0.27 protein_coding missense_variant MODERATE 122A>C Asp41Ala
M0020590 LGPLGOGE_00001 1604 4 Skin 0.27 protein_coding synonymous_variant LOW 87C>T Ala29Ala
M0020591 LGPLGOGE_00001 1618 4 Skin 0.27 protein_coding synonymous_variant LOW 73C>T Leu25Leu
M0020592 LGPLGOGE_00001 1640 4 Skin 0.27 protein_coding synonymous_variant LOW 51C>T Thr17Thr
M0020593 LGPLGOGE_00001 1643 4 Skin 0.27 protein_coding synonymous_variant LOW 48T>C Asp16Asp
M0020594 LGPLGOGE_00001 1645 4 Skin 0.27 protein_coding missense_variant MODERATE 46G>A Asp16Asn
M0020595 LGPLGOGE_00001 1657 4 Skin 0.27 protein_coding missense_variant MODERATE 34A>G Asn12Asp
M0020596 LGPLGOGE_00001 1670 4 Skin 0.27 protein_coding synonymous_variant LOW 21T>C Ile7Ile
M0020597 LGPLGOGE_00001 1708 4 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -18G>A None
M0020598 LGPLGOGE_00001 1767 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -77G>A None
M0020599 LGPLGOGE_00001 1769 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -79G>A None
M0020600 LGPLGOGE_00001 1797 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -107C>T None
M0020601 LGPLGOGE_00002 1840 5 Skin 0.33 protein_coding synonymous_variant LOW 399C>T Ile133Ile
M0020602 LGPLGOGE_00002 1858 5 Skin 0.33 protein_coding synonymous_variant LOW 381C>T Asn127Asn
M0020603 LGPLGOGE_00002 1894 5 Skin 0.33 protein_coding synonymous_variant LOW 345T>C Leu115Leu
M0020604 LGPLGOGE_00002 1898 5 Skin 0.33 protein_coding missense_variant MODERATE 341G>A Arg114Gln
M0020605 LGPLGOGE_00002 1930 5 Skin 0.33 protein_coding synonymous_variant LOW 309T>C Val103Val
M0020606 LGPLGOGE_00002 1960 5 Skin 0.33 protein_coding synonymous_variant LOW 279G>A Gly93Gly
M0020607 LGPLGOGE_00002 1990 5 Skin 0.33 protein_coding synonymous_variant LOW 249A>G Ala83Ala
M0020608 LGPLGOGE_00002 2046 5 Skin 0.33 protein_coding synonymous_variant LOW 193C>T Leu65Leu
M0020609 LGPLGOGE_00002 2133 4 Skin 0.27 protein_coding missense_variant MODERATE 106G>A Val36Ile
M0020610 LGPLGOGE_00002 2188 4 Skin 0.27 protein_coding synonymous_variant LOW 51C>G Ala17Ala
M0020611 LGPLGOGE_00001 2293 4 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -603A>G None
M0020612 LGPLGOGE_00001 2386 6 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -696C>T None
M0020613 LGPLGOGE_00001 2388 6 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -698G>A None
M0020614 LGPLGOGE_00001 2475 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -785G>A None
M0020615 LGPLGOGE_00001 2575 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -885G>A None
M0020616 LGPLGOGE_00001 2661 4 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -971C>G None
M0020617 LGPLGOGE_00001 1442 3 Skin 0.20 protein_coding synonymous_variant LOW 249C>T Thr83Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term