Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1947
  Reference Plasmid   1111525849669879_bin.34__k141_287727
  Reference Plasmid Size   12355
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0020618 LNANHBGA_00002 2097 12 Skin 0.60 protein_coding missense_variant MODERATE 119T>G Leu40Arg
M0020619 LNANHBGA_00003 3779 12 Skin 0.60 protein_coding synonymous_variant LOW 378G>C Leu126Leu
M0020620 LNANHBGA_00003 3962 3 Skin 0.15 protein_coding synonymous_variant LOW 561C>T Gly187Gly
M0020621 LNANHBGA_00003 4469 3 Skin 0.15 protein_coding synonymous_variant LOW 1068C>T Ser356Ser
M0020622 LNANHBGA_00003 4472 3 Skin 0.15 protein_coding synonymous_variant LOW 1071G>C Ala357Ala
M0020623 LNANHBGA_00003 4508 3 Skin 0.15 protein_coding synonymous_variant LOW 1107T>C Val369Val
M0020624 LNANHBGA_00003 4523 3 Skin 0.15 protein_coding synonymous_variant LOW 1122T>C Phe374Phe
M0020625 LNANHBGA_00003 4925 5 Skin 0.25 protein_coding synonymous_variant LOW 1524T>C Gly508Gly
M0020626 LNANHBGA_00006 7407 11 Skin 0.55 protein_coding synonymous_variant LOW 66C>T Gly22Gly
M0020627 LNANHBGA_00006 7410 11 Skin 0.55 protein_coding synonymous_variant LOW 69T>A Gly23Gly
M0020628 LNANHBGA_00006 7746 11 Skin 0.55 protein_coding synonymous_variant LOW 405A>G Glu135Glu
M0020629 LNANHBGA_00006 7782 10 Skin 0.50 protein_coding synonymous_variant LOW 441C>G Pro147Pro
M0020630 LNANHBGA_00006 7791 10 Skin 0.50 protein_coding synonymous_variant LOW 450T>A Leu150Leu
M0020631 LNANHBGA_00006 7827 10 Skin 0.50 protein_coding synonymous_variant LOW 486C>G Arg162Arg
M0020632 LNANHBGA_00006 7842 10 Skin 0.50 protein_coding synonymous_variant LOW 501C>T Asn167Asn
M0020633 LNANHBGA_00006 7866 10 Skin 0.50 protein_coding synonymous_variant LOW 525A>G Glu175Glu
M0020634 LNANHBGA_00007 8888 4 Skin 0.20 protein_coding synonymous_variant LOW 825T>C Thr275Thr
M0020635 LNANHBGA_00007 8906 4 Skin 0.20 protein_coding synonymous_variant LOW 843A>G Glu281Glu
M0020636 LNANHBGA_00007 8915 4 Skin 0.20 protein_coding synonymous_variant LOW 852C>T Gly284Gly
M0020637 LNANHBGA_00007 8916 4 Skin 0.20 protein_coding missense_variant MODERATE 853G>C Glu285Gln
M0020638 LNANHBGA_00002 3202 3 Skin 0.15 protein_coding synonymous_variant LOW 1224C>G Val408Val
M0020639 LNANHBGA_00002 3208 3 Skin 0.15 protein_coding synonymous_variant LOW 1230T>G Val410Val
M0020640 LNANHBGA_00003 4619 3 Skin 0.15 protein_coding synonymous_variant LOW 1218C>G Val406Val
M0020641 LNANHBGA_00003 4643 3 Skin 0.15 protein_coding synonymous_variant LOW 1242C>T Thr414Thr
M0020642 LNANHBGA_00003 4673 3 Skin 0.15 protein_coding missense_variant MODERATE 1272C>G Asp424Glu
M0020643 LNANHBGA_00003 4274 3 Skin 0.15 protein_coding synonymous_variant LOW 873C>T Ile291Ile
M0020644 LNANHBGA_00003 4283 3 Skin 0.15 protein_coding synonymous_variant LOW 882G>C Ala294Ala
M0020645 LNANHBGA_00005 6608 3 Skin 0.15 protein_coding synonymous_variant LOW 510C>G Ala170Ala
M0020646 LNANHBGA_00005 6611 3 Skin 0.15 protein_coding synonymous_variant LOW 513G>C Leu171Leu
M0020647 LNANHBGA_00005 6617 3 Skin 0.15 protein_coding synonymous_variant LOW 519C>T Val173Val
M0020648 LNANHBGA_00005 6626 4 Skin 0.20 protein_coding synonymous_variant LOW 528A>G Ala176Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term