Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1969
  Reference Plasmid   1111525849736171_bin.24__k141_86338
  Reference Plasmid Size   7763
  Reference Plasmid GC Content   0.53
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0021614 FGIPIJMC_00003 2158 6 Skin 0.40 protein_coding synonymous_variant LOW 576A>G Ala192Ala
M0021615 FGIPIJMC_00003 2224 6 Skin 0.40 protein_coding synonymous_variant LOW 510G>A Leu170Leu
M0021616 FGIPIJMC_00004 3248 4 Skin 0.27 protein_coding synonymous_variant LOW 534A>G Ser178Ser
M0021617 FGIPIJMC_00004 3290 6 Skin 0.40 protein_coding synonymous_variant LOW 492C>A Val164Val
M0021618 FGIPIJMC_00004 3548 7 Skin 0.47 protein_coding synonymous_variant LOW 234T>C Phe78Phe
M0021619 FGIPIJMC_00004 3575 5 Skin 0.33 protein_coding synonymous_variant LOW 207C>A Ile69Ile
M0021620 FGIPIJMC_00004 3749 8 Skin 0.53 protein_coding synonymous_variant LOW 33A>G Gly11Gly
M0021621 FGIPIJMC_00005 4202 7 Skin 0.47 protein_coding missense_variant MODERATE 113C>A Thr38Lys
M0021622 FGIPIJMC_00006 4890 6 Skin 0.40 protein_coding synonymous_variant LOW 1350G>A Leu450Leu
M0021623 FGIPIJMC_00006 4971 6 Skin 0.40 protein_coding synonymous_variant LOW 1269C>T Arg423Arg
M0021624 FGIPIJMC_00006 5781 7 Skin 0.47 protein_coding synonymous_variant LOW 459T>C Thr153Thr
M0021625 FGIPIJMC_00008 6767 3 Skin 0.20 protein_coding synonymous_variant LOW 192A>G Glu64Glu
M0021626 FGIPIJMC_00008 6800 3 Skin 0.20 protein_coding synonymous_variant LOW 225A>C Ala75Ala
M0021627 FGIPIJMC_00008 6830 3 Skin 0.20 protein_coding synonymous_variant LOW 255T>C Ser85Ser
M0021628 FGIPIJMC_00008 6851 3 Skin 0.20 protein_coding synonymous_variant LOW 276C>T Gly92Gly
M0021629 FGIPIJMC_00008 6857 3 Skin 0.20 protein_coding synonymous_variant LOW 282G>A Val94Val
M0021630 FGIPIJMC_00008 6872 3 Skin 0.20 protein_coding synonymous_variant LOW 297G>A Thr99Thr
M0021631 FGIPIJMC_00008 6884 3 Skin 0.20 protein_coding synonymous_variant LOW 309T>A Ala103Ala
M0021632 FGIPIJMC_00008 6887 3 Skin 0.20 protein_coding synonymous_variant LOW 312A>G Glu104Glu
M0021633 FGIPIJMC_00008 6906 3 Skin 0.20 protein_coding synonymous_variant LOW 331T>C Leu111Leu
M0021634 FGIPIJMC_00008 6913 3 Skin 0.20 protein_coding missense_variant MODERATE 338C>T Ala113Val
M0021635 FGIPIJMC_00005 4307 3 Skin 0.20 protein_coding missense_variant MODERATE 8A>G Lys3Arg
M0021636 FGIPIJMC_00006 5697 6 Skin 0.40 protein_coding synonymous_variant LOW 543C>T Cys181Cys
M0021637 FGIPIJMC_00006 5814 6 Skin 0.40 protein_coding synonymous_variant LOW 426A>G Gln142Gln
M0021638 FGIPIJMC_00001 158 4 Skin 0.27 protein_coding synonymous_variant LOW 93A>T Ser31Ser
M0021639 FGIPIJMC_00001 590 4 Skin 0.27 protein_coding synonymous_variant LOW 525A>C Ser175Ser
M0021640 FGIPIJMC_00001 615 4 Skin 0.27 protein_coding missense_variant MODERATE 550A>C Lys184Gln
M0021641 FGIPIJMC_00002 952 5 Skin 0.33 protein_coding synonymous_variant LOW 312A>G Val104Val
M0021642 FGIPIJMC_00002 1326 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -63C>A None
M0021643 FGIPIJMC_00002 1327 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -64G>T None
M0021644 FGIPIJMC_00002 1460 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -197G>T None
M0021645 FGIPIJMC_00006 4740 4 Skin 0.27 protein_coding synonymous_variant LOW 1500A>G Glu500Glu
M0021646 FGIPIJMC_00006 4745 4 Skin 0.27 protein_coding missense_variant MODERATE 1495A>G Met499Val
M0021647 FGIPIJMC_00006 5061 5 Skin 0.33 protein_coding synonymous_variant LOW 1179C>T Asn393Asn
M0021648 FGIPIJMC_00002 1045 5 Skin 0.33 protein_coding synonymous_variant LOW 219A>G Leu73Leu
M0021649 FGIPIJMC_00002 1063 5 Skin 0.33 protein_coding synonymous_variant LOW 201T>C Ile67Ile
M0021650 FGIPIJMC_00003 1848 3 Skin 0.20 protein_coding missense_variant MODERATE 886C>T His296Tyr
M0021651 FGIPIJMC_00005 4057 4 Skin 0.27 protein_coding synonymous_variant LOW 258T>C Val86Val
M0021652 FGIPIJMC_00005 4096 4 Skin 0.27 protein_coding synonymous_variant LOW 219C>T His73His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term