Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1974
  Reference Plasmid   1111525849736575_bin.22__k141_831924
  Reference Plasmid Size   6866
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0021667 OEGNMMKJ_00001 294 3 Skin 0.07 protein_coding synonymous_variant LOW 234C>A Thr78Thr
M0021668 OEGNMMKJ_00001 318 3 Skin 0.07 protein_coding synonymous_variant LOW 210C>T Gly70Gly
M0021669 OEGNMMKJ_00001 332 3 Skin 0.07 protein_coding missense_variant MODERATE 196A>G Ser66Gly
M0021670 OEGNMMKJ_00001 336 3 Skin 0.07 protein_coding synonymous_variant LOW 192A>G Ala64Ala
M0021671 OEGNMMKJ_00001 347 3 Skin 0.07 protein_coding synonymous_variant LOW 181T>C Leu61Leu
M0021672 OEGNMMKJ_00001 381 4 Skin 0.09 protein_coding synonymous_variant LOW 147T>C Ser49Ser
M0021673 OEGNMMKJ_00001 409 4 Skin 0.09 protein_coding missense_variant MODERATE 119T>C Val40Ala
M0021674 OEGNMMKJ_00001 668 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -141G>T None
M0021675 OEGNMMKJ_00001 681 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -154A>G None
M0021676 OEGNMMKJ_00001 684 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -157G>T None
M0021677 OEGNMMKJ_00001 700 11 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -173A>C None
M0021678 OEGNMMKJ_00001 703 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -176A>G None
M0021679 OEGNMMKJ_00001 713 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -186T>C None
M0021680 OEGNMMKJ_00001 715 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -188A>G None
M0021681 OEGNMMKJ_00001 729 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -202A>G None
M0021682 OEGNMMKJ_00002 735 7 Skin 0.15 protein_coding synonymous_variant LOW 6G>A Lys2Lys
M0021683 OEGNMMKJ_00002 741 7 Skin 0.15 protein_coding synonymous_variant LOW 12G>C Ala4Ala
M0021684 OEGNMMKJ_00002 939 3 Skin 0.07 protein_coding synonymous_variant LOW 210C>T Leu70Leu
M0021685 OEGNMMKJ_00002 1002 10 Skin 0.22 protein_coding synonymous_variant LOW 273T>C Ile91Ile
M0021686 OEGNMMKJ_00002 1029 10 Skin 0.22 protein_coding synonymous_variant LOW 300G>A Ala100Ala
M0021687 OEGNMMKJ_00002 1053 11 Skin 0.24 protein_coding synonymous_variant LOW 324C>G Leu108Leu
M0021688 OEGNMMKJ_00002 1183 6 Skin 0.13 protein_coding missense_variant MODERATE 454C>G His152Asp
M0021689 OEGNMMKJ_00002 1221 4 Skin 0.09 protein_coding synonymous_variant LOW 492T>C Gly164Gly
M0021690 OEGNMMKJ_00002 1254 4 Skin 0.09 protein_coding synonymous_variant LOW 525C>T Gly175Gly
M0021691 OEGNMMKJ_00002 1280 4 Skin 0.09 protein_coding missense_variant MODERATE 551G>C Ser184Thr
M0021692 OEGNMMKJ_00002 1887 14 Skin 0.30 protein_coding synonymous_variant LOW 1158C>T Ile386Ile
M0021693 OEGNMMKJ_00002 1977 6 Skin 0.13 protein_coding synonymous_variant LOW 1248C>T Asn416Asn
M0021694 OEGNMMKJ_00001 2038 9 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -1511T>C None
M0021695 OEGNMMKJ_00003 2077 9 Skin 0.20 protein_coding missense_variant MODERATE 28A>C Ile10Leu
M0021696 OEGNMMKJ_00003 2079 9 Skin 0.20 protein_coding synonymous_variant LOW 30C>T Ile10Ile
M0021697 OEGNMMKJ_00003 2091 9 Skin 0.20 protein_coding synonymous_variant LOW 42C>T Ala14Ala
M0021698 OEGNMMKJ_00003 2101 9 Skin 0.20 protein_coding missense_variant MODERATE 52G>A Ala18Thr
M0021699 OEGNMMKJ_00003 2232 7 Skin 0.15 protein_coding synonymous_variant LOW 183C>T Tyr61Tyr
M0021700 OEGNMMKJ_00003 2271 12 Skin 0.26 protein_coding synonymous_variant LOW 222T>C Val74Val
M0021701 OEGNMMKJ_00003 3021 22 Skin 0.48 protein_coding synonymous_variant LOW 972C>T Gly324Gly
M0021702 OEGNMMKJ_00004 3424 28 Skin 0.61 protein_coding synonymous_variant LOW 243T>C Gly81Gly
M0021703 OEGNMMKJ_00005 3994 17 Skin 0.37 protein_coding synonymous_variant LOW 90C>T Thr30Thr
M0021704 OEGNMMKJ_00001 5330 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4803C>T None
M0021705 OEGNMMKJ_00008 6026 19 Skin 0.41 protein_coding synonymous_variant LOW 585G>A Val195Val
M0021706 OEGNMMKJ_00002 1351 13 Skin 0.28 protein_coding missense_variant MODERATE 622T>G Cys208Gly
M0021707 OEGNMMKJ_00002 1356 13 Skin 0.28 protein_coding synonymous_variant LOW 627C>T Ala209Ala
M0021708 OEGNMMKJ_00002 1686 10 Skin 0.22 protein_coding synonymous_variant LOW 957T>C Gly319Gly
M0021709 OEGNMMKJ_00003 2319 14 Skin 0.30 protein_coding synonymous_variant LOW 270T>C Ala90Ala
M0021710 OEGNMMKJ_00004 3373 24 Skin 0.52 protein_coding synonymous_variant LOW 192C>T Tyr64Tyr
M0021711 OEGNMMKJ_00002 1656 10 Skin 0.22 protein_coding synonymous_variant LOW 927T>C Arg309Arg
M0021712 OEGNMMKJ_00003 2425 8 Skin 0.17 protein_coding missense_variant MODERATE 376G>A Ala126Thr
M0021713 OEGNMMKJ_00003 2442 8 Skin 0.17 protein_coding synonymous_variant LOW 393A>G Gln131Gln
M0021714 OEGNMMKJ_00003 2550 11 Skin 0.24 protein_coding synonymous_variant LOW 501T>C Asn167Asn
M0021715 OEGNMMKJ_00007 5179 11 Skin 0.24 protein_coding synonymous_variant LOW 606G>T Val202Val
M0021716 OEGNMMKJ_00008 5588 19 Skin 0.41 protein_coding synonymous_variant LOW 1023C>G Ser341Ser
M0021717 OEGNMMKJ_00008 5896 12 Skin 0.26 protein_coding synonymous_variant LOW 715C>T Leu239Leu
M0021718 OEGNMMKJ_00008 5963 9 Skin 0.20 protein_coding synonymous_variant LOW 648G>A Ala216Ala
M0021719 OEGNMMKJ_00008 6100 9 Skin 0.20 protein_coding missense_variant MODERATE 511A>C Met171Leu
M0021720 OEGNMMKJ_00008 6185 10 Skin 0.22 protein_coding synonymous_variant LOW 426C>T Arg142Arg
M0021721 OEGNMMKJ_00008 6239 22 Skin 0.48 protein_coding synonymous_variant LOW 372T>G Ala124Ala
M0021722 OEGNMMKJ_00008 6265 22 Skin 0.48 protein_coding synonymous_variant LOW 346T>C Leu116Leu
M0021723 OEGNMMKJ_00008 6317 12 Skin 0.26 protein_coding synonymous_variant LOW 294T>G Ala98Ala
M0021724 OEGNMMKJ_00008 6330 12 Skin 0.26 protein_coding missense_variant MODERATE 281C>T Ala94Val
M0021725 OEGNMMKJ_00008 6591 9 Skin 0.20 protein_coding missense_variant MODERATE 20T>C Phe7Ser
M0021726 OEGNMMKJ_00002 1584 7 Skin 0.15 protein_coding synonymous_variant LOW 855A>G Arg285Arg
M0021727 OEGNMMKJ_00004 3241 14 Skin 0.30 protein_coding synonymous_variant LOW 60C>G Leu20Leu
M0021728 OEGNMMKJ_00004 3274 13 Skin 0.28 protein_coding synonymous_variant LOW 93C>G Thr31Thr
M0021729 OEGNMMKJ_00004 3763 13 Skin 0.28 protein_coding synonymous_variant LOW 582G>C Ser194Ser
M0021730 OEGNMMKJ_00004 3764 13 Skin 0.28 protein_coding missense_variant MODERATE 583C>A Leu195Met
M0021731 OEGNMMKJ_00001 3827 11 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -3300G>A None
M0021732 OEGNMMKJ_00001 3847 11 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -3320C>T None
M0021733 OEGNMMKJ_00001 3896 13 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -3369C>T None
M0021734 OEGNMMKJ_00003 2751 6 Skin 0.13 protein_coding synonymous_variant LOW 702G>A Ala234Ala
M0021735 OEGNMMKJ_00003 2802 8 Skin 0.17 protein_coding synonymous_variant LOW 753A>G Pro251Pro
M0021736 OEGNMMKJ_00003 2826 7 Skin 0.15 protein_coding synonymous_variant LOW 777G>A Gln259Gln
M0021737 OEGNMMKJ_00003 2952 7 Skin 0.15 protein_coding synonymous_variant LOW 903C>T Asp301Asp
M0021738 OEGNMMKJ_00004 3743 12 Skin 0.26 protein_coding missense_variant MODERATE 562A>G Thr188Ala
M0021739 OEGNMMKJ_00004 3758 12 Skin 0.26 protein_coding missense_variant MODERATE 577A>G Ser193Gly
M0021740 OEGNMMKJ_00001 3938 12 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -3411A>C None
M0021741 OEGNMMKJ_00001 4332 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -3805C>T None
M0021742 OEGNMMKJ_00007 4918 16 Skin 0.35 protein_coding synonymous_variant LOW 345T>C Thr115Thr
M0021743 OEGNMMKJ_00007 4936 16 Skin 0.35 protein_coding synonymous_variant LOW 363A>G Gly121Gly
M0021744 OEGNMMKJ_00008 6197 12 Skin 0.26 protein_coding synonymous_variant LOW 414G>A Val138Val
M0021745 OEGNMMKJ_00005 6702 8 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -2619G>A None
M0021746 OEGNMMKJ_00005 6703 8 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -2620C>A None
M0021747 OEGNMMKJ_00005 6708 8 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -2625A>T None
M0021748 OEGNMMKJ_00005 6712 14 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -2629G>A None
M0021749 OEGNMMKJ_00001 552 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -25C>A None
M0021750 OEGNMMKJ_00001 553 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -26G>T None
M0021751 OEGNMMKJ_00001 564 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -37A>G None
M0021752 OEGNMMKJ_00005 6774 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -2691G>A None
M0021753 OEGNMMKJ_00003 2363 3 Skin 0.07 protein_coding missense_variant MODERATE 314A>G Asp105Gly
M0021754 OEGNMMKJ_00002 1470 7 Skin 0.15 protein_coding synonymous_variant LOW 741A>G Glu247Glu
M0021755 OEGNMMKJ_00002 1497 8 Skin 0.17 protein_coding synonymous_variant LOW 768G>T Pro256Pro
M0021756 OEGNMMKJ_00002 1530 8 Skin 0.17 protein_coding synonymous_variant LOW 801A>G Lys267Lys
M0021757 OEGNMMKJ_00005 6718 6 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -2635G>C None
M0021758 OEGNMMKJ_00005 6729 6 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -2646C>A None
M0021759 OEGNMMKJ_00005 6731 6 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -2648C>T None
M0021760 OEGNMMKJ_00005 6815 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -2732C>G None
M0021761 OEGNMMKJ_00004 3517 6 Skin 0.13 protein_coding synonymous_variant LOW 336G>A Leu112Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term