Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1977
  Reference Plasmid   1111525849736575_bin.9__k141_15879
  Reference Plasmid Size   27206
  Reference Plasmid GC Content   0.52
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0021801 ODBHLOBF_00003 2362 9 Skin 0.24 protein_coding missense_variant MODERATE 132T>A Asp44Glu
M0021802 ODBHLOBF_00006 5336 9 Skin 0.24 protein_coding synonymous_variant LOW 276A>C Ile92Ile
M0021803 ODBHLOBF_00014 13313 13 Skin 0.35 protein_coding synonymous_variant LOW 598T>C Leu200Leu
M0021804 ODBHLOBF_00022 17192 3 Skin 0.08 protein_coding splice_region_variant&stop_retained_variant LOW 1191G>A Ter397Ter
M0021805 ODBHLOBF_00022 17193 3 Skin 0.08 protein_coding stop_lost&splice_region_variant HIGH 1190A>G Ter397Trpext*?
M0021806 ODBHLOBF_00022 17211 3 Skin 0.08 protein_coding missense_variant MODERATE 1172T>A Leu391Gln
M0021807 ODBHLOBF_00022 17219 3 Skin 0.08 protein_coding synonymous_variant LOW 1164G>A Leu388Leu
M0021808 ODBHLOBF_00022 17236 3 Skin 0.08 protein_coding synonymous_variant LOW 1147C>T Leu383Leu
M0021809 ODBHLOBF_00022 17248 3 Skin 0.08 protein_coding missense_variant MODERATE 1135T>C Phe379Leu
M0021810 ODBHLOBF_00030 24296 7 Skin 0.19 protein_coding synonymous_variant LOW 87T>C Ala29Ala
M0021811 ODBHLOBF_00030 25187 5 Skin 0.14 protein_coding synonymous_variant LOW 978A>T Ser326Ser
M0021812 ODBHLOBF_00031 25530 3 Skin 0.08 protein_coding missense_variant MODERATE 172G>A Gly58Ser
M0021813 ODBHLOBF_00032 25899 3 Skin 0.08 protein_coding synonymous_variant LOW 1263G>A Leu421Leu
M0021814 ODBHLOBF_00020 16675 5 Skin 0.14 protein_coding synonymous_variant LOW 399G>C Arg133Arg
M0021815 ODBHLOBF_00022 17302 10 Skin 0.27 protein_coding synonymous_variant LOW 1081C>T Leu361Leu
M0021816 ODBHLOBF_00022 17366 6 Skin 0.16 protein_coding synonymous_variant LOW 1017A>G Ala339Ala
M0021817 ODBHLOBF_00022 17432 5 Skin 0.14 protein_coding synonymous_variant LOW 951T>C Ser317Ser
M0021818 ODBHLOBF_00022 17477 5 Skin 0.14 protein_coding synonymous_variant LOW 906A>G Pro302Pro
M0021819 ODBHLOBF_00030 24249 5 Skin 0.14 protein_coding missense_variant MODERATE 40T>A Cys14Ser
M0021820 ODBHLOBF_00030 24536 5 Skin 0.14 protein_coding synonymous_variant LOW 327C>G Thr109Thr
M0021821 ODBHLOBF_00022 17852 3 Skin 0.08 protein_coding synonymous_variant LOW 531A>G Leu177Leu
M0021822 ODBHLOBF_00022 17990 6 Skin 0.16 protein_coding synonymous_variant LOW 393A>G Thr131Thr
M0021823 ODBHLOBF_00022 18040 4 Skin 0.11 protein_coding synonymous_variant LOW 343C>T Leu115Leu
M0021824 ODBHLOBF_00022 18058 4 Skin 0.11 protein_coding synonymous_variant LOW 325T>C Leu109Leu
M0021825 ODBHLOBF_00022 18068 5 Skin 0.14 protein_coding synonymous_variant LOW 315C>T Gly105Gly
M0021826 ODBHLOBF_00022 18329 5 Skin 0.14 protein_coding synonymous_variant LOW 54A>G Leu18Leu
M0021827 ODBHLOBF_00023 19137 4 Skin 0.11 protein_coding synonymous_variant LOW 354G>T Thr118Thr
M0021828 ODBHLOBF_00024 19685 3 Skin 0.08 protein_coding synonymous_variant LOW 66T>C Val22Val
M0021829 ODBHLOBF_00024 19711 3 Skin 0.08 protein_coding missense_variant MODERATE 92C>A Ala31Asp
M0021830 ODBHLOBF_00024 19715 3 Skin 0.08 protein_coding synonymous_variant LOW 96C>T Gly32Gly
M0021831 ODBHLOBF_00022 17290 5 Skin 0.14 protein_coding missense_variant MODERATE 1093T>A Ser365Thr
M0021832 ODBHLOBF_00022 17315 6 Skin 0.16 protein_coding synonymous_variant LOW 1068G>A Pro356Pro
M0021833 ODBHLOBF_00026 22027 4 Skin 0.11 protein_coding synonymous_variant LOW 405C>T Ile135Ile
M0021834 ODBHLOBF_00026 22111 3 Skin 0.08 protein_coding synonymous_variant LOW 489C>T Phe163Phe
M0021835 ODBHLOBF_00026 22366 8 Skin 0.22 protein_coding synonymous_variant LOW 744T>C Pro248Pro
M0021836 ODBHLOBF_00026 22746 5 Skin 0.14 protein_coding missense_variant MODERATE 1124C>T Ala375Val
M0021837 ODBHLOBF_00026 22750 5 Skin 0.14 protein_coding synonymous_variant LOW 1128C>T Phe376Phe
M0021838 ODBHLOBF_00026 22996 6 Skin 0.16 protein_coding synonymous_variant LOW 1374T>C Asp458Asp
M0021839 ODBHLOBF_00022 17642 4 Skin 0.11 protein_coding synonymous_variant LOW 741C>T Gly247Gly
M0021840 ODBHLOBF_00022 17666 3 Skin 0.08 protein_coding synonymous_variant LOW 717C>T Ile239Ile
M0021841 ODBHLOBF_00024 20461 3 Skin 0.08 protein_coding missense_variant MODERATE 842T>G Leu281Arg
M0021842 ODBHLOBF_00024 20504 3 Skin 0.08 protein_coding synonymous_variant LOW 885G>A Gln295Gln
M0021843 ODBHLOBF_00025 21139 3 Skin 0.08 protein_coding synonymous_variant LOW 378T>A Val126Val
M0021844 ODBHLOBF_00025 21303 5 Skin 0.14 protein_coding synonymous_variant LOW 214T>C Leu72Leu
M0021845 ODBHLOBF_00025 21325 5 Skin 0.14 protein_coding synonymous_variant LOW 192C>G Arg64Arg
M0021846 ODBHLOBF_00025 21334 5 Skin 0.14 protein_coding synonymous_variant LOW 183G>A Ala61Ala
M0021847 ODBHLOBF_00029 23895 4 Skin 0.11 protein_coding synonymous_variant LOW 171A>G Lys57Lys
M0021848 ODBHLOBF_00032 26075 3 Skin 0.08 protein_coding missense_variant MODERATE 1087C>A His363Asn
M0021849 ODBHLOBF_00032 26416 3 Skin 0.08 protein_coding missense_variant MODERATE 746C>T Ala249Val
M0021850 ODBHLOBF_00025 20830 3 Skin 0.08 protein_coding synonymous_variant LOW 687G>C Leu229Leu
M0021851 ODBHLOBF_00025 21052 3 Skin 0.08 protein_coding synonymous_variant LOW 465A>G Ala155Ala
M0021852 ODBHLOBF_00025 20893 3 Skin 0.08 protein_coding missense_variant MODERATE 624C>A His208Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
ODBHLOBF_00012 Cadmium (Cd), Zinc (Zn) 70.8 5.3e-93 5 216 0.9815 0.9815 experiment
ODBHLOBF_00012 Cadmium (Cd), Zinc (Zn) 77.3 6.4e-100 1 216 1.0000 1.0000 prediction
ODBHLOBF_00029 Hydrochloric acid (HCl) [class: Acid] 77.3 3.7e-36 1 159 1.0252 1.0795 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term