Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1989
  Reference Plasmid   1111525849736655_bin.25__k141_236379
  Reference Plasmid Size   7578
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0021894 FGANOFBA_00004 264 4 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -3251G>A None
M0021895 FGANOFBA_00004 3558 12 Skin 0.60 protein_coding missense_variant MODERATE 44C>G Ala15Gly
M0021896 FGANOFBA_00004 3559 12 Skin 0.60 protein_coding synonymous_variant LOW 45C>T Ala15Ala
M0021897 FGANOFBA_00004 3574 12 Skin 0.60 protein_coding synonymous_variant LOW 60G>A Ser20Ser
M0021898 FGANOFBA_00001 5399 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4317G>A None
M0021899 FGANOFBA_00001 5402 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4320C>T None
M0021900 FGANOFBA_00001 5403 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4321A>G None
M0021901 FGANOFBA_00001 5409 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4327A>C None
M0021902 FGANOFBA_00001 5417 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4335G>A None
M0021903 FGANOFBA_00001 5418 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4336C>T None
M0021904 FGANOFBA_00001 5470 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4388T>A None
M0021905 FGANOFBA_00005 5535 3 Skin 0.15 protein_coding missense_variant MODERATE 26G>A Ser9Asn
M0021906 FGANOFBA_00005 5574 3 Skin 0.15 protein_coding missense_variant MODERATE 65G>C Ser22Thr
M0021907 FGANOFBA_00006 5675 5 Skin 0.25 protein_coding synonymous_variant LOW 63G>A Val21Val
M0021908 FGANOFBA_00006 5681 5 Skin 0.25 protein_coding missense_variant MODERATE 57T>A Ser19Arg
M0021909 FGANOFBA_00006 5690 5 Skin 0.25 protein_coding missense_variant MODERATE 48G>C Met16Ile
M0021910 FGANOFBA_00006 5714 5 Skin 0.25 protein_coding synonymous_variant LOW 24A>G Val8Val
M0021911 FGANOFBA_00007 5745 4 Skin 0.20 protein_coding missense_variant MODERATE 121A>G Ile41Val
M0021912 FGANOFBA_00007 5748 4 Skin 0.20 protein_coding missense_variant MODERATE 118C>T Arg40Trp
M0021913 FGANOFBA_00007 5751 4 Skin 0.20 protein_coding missense_variant MODERATE 115A>G Met39Val
M0021914 FGANOFBA_00007 5809 4 Skin 0.20 protein_coding synonymous_variant LOW 57G>A Arg19Arg
M0021915 FGANOFBA_00007 5828 4 Skin 0.20 protein_coding missense_variant MODERATE 38C>T Thr13Ile
M0021916 FGANOFBA_00001 5630 3 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4548G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FGANOFBA_00003 3.A.1.210.11 70.2 9.1e-235 1 606 1.0000 0.9984 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily