Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1998
  Reference Plasmid   1111525849736752_bin.43__k141_295459
  Reference Plasmid Size   24222
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022150 EFCKKOPK_00013 11478 3 Skin 0.30 protein_coding missense_variant MODERATE 1094A>G Asp365Gly
M0022151 EFCKKOPK_00014 12365 4 Skin 0.40 protein_coding missense_variant MODERATE 542T>G Leu181Arg
M0022152 EFCKKOPK_00017 15537 4 Skin 0.40 protein_coding missense_variant MODERATE 428A>G Glu143Gly
M0022153 EFCKKOPK_00019 17391 3 Skin 0.30 protein_coding missense_variant MODERATE 1030G>C Ala344Pro
M0022154 EFCKKOPK_00019 18117 4 Skin 0.40 protein_coding missense_variant MODERATE 304A>T Asn102Tyr
M0022155 EFCKKOPK_00019 18213 3 Skin 0.30 protein_coding missense_variant MODERATE 208A>G Thr70Ala
M0022156 EFCKKOPK_00022 20406 3 Skin 0.30 protein_coding missense_variant MODERATE 941G>A Gly314Glu
M0022157 EFCKKOPK_00025 23172 3 Skin 0.30 protein_coding synonymous_variant LOW 933C>A Arg311Arg
M0022158 EFCKKOPK_00025 23706 3 Skin 0.30 protein_coding synonymous_variant LOW 399C>T Thr133Thr
M0022159 EFCKKOPK_00010 9045 3 Skin 0.30 protein_coding synonymous_variant LOW 1060T>C Leu354Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
EFCKKOPK_00019 Nickel (Ni), Cobalt (Co) 71.2 3.6e-144 1 396 0.9682 0.9754 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
EFCKKOPK_00010 QHC02316.1|GH184 100 0 1 548 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term