Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2005
  Reference Plasmid   1111525849736894_bin.28__k141_1302796
  Reference Plasmid Size   5689
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022185 JIBIPCOO_00004 2134 8 Skin 0.24 protein_coding synonymous_variant LOW 228G>A Thr76Thr
M0022186 JIBIPCOO_00005 2524 29 Skin 0.85 protein_coding missense_variant MODERATE 1181T>C Ile394Thr
M0022187 JIBIPCOO_00004 1802 4 Skin 0.12 protein_coding missense_variant MODERATE 560C>T Thr187Ile
M0022188 JIBIPCOO_00005 2881 3 Skin 0.09 protein_coding missense_variant MODERATE 824C>T Ala275Val
M0022189 JIBIPCOO_00004 1747 4 Skin 0.12 protein_coding missense_variant MODERATE 615C>A Phe205Leu
M0022190 JIBIPCOO_00004 2025 3 Skin 0.09 protein_coding missense_variant MODERATE 337G>T Asp113Tyr
M0022191 JIBIPCOO_00005 2752 3 Skin 0.09 protein_coding missense_variant MODERATE 953T>G Ile318Ser
M0022192 JIBIPCOO_00006 4022 13 Skin 0.38 protein_coding missense_variant MODERATE 299A>C Glu100Ala
M0022193 JIBIPCOO_00006 4075 4 Skin 0.12 protein_coding synonymous_variant LOW 246C>T Ala82Ala
M0022194 JIBIPCOO_00005 3630 5 Skin 0.15 protein_coding synonymous_variant LOW 75A>G Arg25Arg
M0022195 JIBIPCOO_00006 4283 4 Skin 0.12 protein_coding missense_variant MODERATE 38C>G Pro13Arg
M0022196 JIBIPCOO_00003 988 4 Skin 0.12 protein_coding missense_variant MODERATE 627G>C Trp209Cys
M0022197 JIBIPCOO_00004 2157 4 Skin 0.12 protein_coding missense_variant MODERATE 205A>G Thr69Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term