Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2007
  Reference Plasmid   1111525849736894_bin.7__k141_347913
  Reference Plasmid Size   15897
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022201 MIFKINMO_00006 9157 3 Skin 0.50 protein_coding synonymous_variant LOW 3759G>T Thr1253Thr
M0022202 MIFKINMO_00006 9328 3 Skin 0.50 protein_coding synonymous_variant LOW 3930G>C Ala1310Ala
M0022203 MIFKINMO_00006 9331 3 Skin 0.50 protein_coding synonymous_variant LOW 3933T>C Asn1311Asn
M0022204 MIFKINMO_00006 9340 3 Skin 0.50 protein_coding synonymous_variant LOW 3942G>T Gly1314Gly
M0022205 MIFKINMO_00006 9346 3 Skin 0.50 protein_coding synonymous_variant LOW 3948G>C Val1316Val
M0022206 MIFKINMO_00006 9361 3 Skin 0.50 protein_coding synonymous_variant LOW 3963T>C Asn1321Asn
M0022207 MIFKINMO_00006 9376 3 Skin 0.50 protein_coding synonymous_variant LOW 3978A>C Gly1326Gly
M0022208 MIFKINMO_00006 9388 3 Skin 0.50 protein_coding synonymous_variant LOW 3990T>C Arg1330Arg
M0022209 MIFKINMO_00006 9406 3 Skin 0.50 protein_coding synonymous_variant LOW 4008A>G Gln1336Gln
M0022210 MIFKINMO_00006 9409 3 Skin 0.50 protein_coding synonymous_variant LOW 4011C>A Ala1337Ala
M0022211 MIFKINMO_00006 9433 3 Skin 0.50 protein_coding synonymous_variant LOW 4035A>G Glu1345Glu
M0022212 MIFKINMO_00006 9460 3 Skin 0.50 protein_coding synonymous_variant LOW 4062A>G Glu1354Glu
M0022213 MIFKINMO_00006 9535 4 Skin 0.67 protein_coding synonymous_variant LOW 4137C>G Ser1379Ser
M0022214 MIFKINMO_00006 10070 4 Skin 0.67 protein_coding missense_variant MODERATE 4672A>G Met1558Val
M0022215 MIFKINMO_00007 11029 4 Skin 0.67 protein_coding missense_variant MODERATE 254A>G Asp85Gly
M0022216 MIFKINMO_00007 11048 4 Skin 0.67 protein_coding synonymous_variant LOW 273C>T Ala91Ala
M0022217 MIFKINMO_00007 11106 3 Skin 0.50 protein_coding missense_variant MODERATE 331G>T Ala111Ser
M0022218 MIFKINMO_00007 11171 4 Skin 0.67 protein_coding synonymous_variant LOW 396G>A Ala132Ala
M0022219 MIFKINMO_00007 11188 4 Skin 0.67 protein_coding missense_variant MODERATE 413G>C Arg138Pro
M0022220 MIFKINMO_00007 11196 4 Skin 0.67 protein_coding missense_variant MODERATE 421A>G Ser141Gly
M0022221 MIFKINMO_00008 11503 4 Skin 0.67 protein_coding synonymous_variant LOW 39A>G Gln13Gln
M0022222 MIFKINMO_00008 11533 4 Skin 0.67 protein_coding synonymous_variant LOW 69A>G Gln23Gln
M0022223 MIFKINMO_00008 11551 4 Skin 0.67 protein_coding synonymous_variant LOW 87A>C Ala29Ala
M0022224 MIFKINMO_00008 11585 3 Skin 0.50 protein_coding synonymous_variant LOW 121T>C Leu41Leu
M0022225 MIFKINMO_00008 11779 3 Skin 0.50 protein_coding synonymous_variant LOW 315A>G Pro105Pro
M0022226 MIFKINMO_00008 11879 5 Skin 0.83 protein_coding missense_variant MODERATE 415T>G Phe139Val
M0022227 MIFKINMO_00008 11911 3 Skin 0.50 protein_coding synonymous_variant LOW 447A>G Arg149Arg
M0022228 MIFKINMO_00008 11950 4 Skin 0.67 protein_coding synonymous_variant LOW 486A>G Glu162Glu
M0022229 MIFKINMO_00008 12067 3 Skin 0.50 protein_coding synonymous_variant LOW 603C>A Ser201Ser
M0022230 MIFKINMO_00008 12089 4 Skin 0.67 protein_coding synonymous_variant LOW 625T>C Leu209Leu
M0022231 MIFKINMO_00009 12848 4 Skin 0.67 protein_coding missense_variant MODERATE 277A>C Met93Leu
M0022232 MIFKINMO_00009 12867 4 Skin 0.67 protein_coding synonymous_variant LOW 258G>A Ala86Ala
M0022233 MIFKINMO_00009 12870 4 Skin 0.67 protein_coding synonymous_variant LOW 255T>C Ala85Ala
M0022234 MIFKINMO_00009 12918 4 Skin 0.67 protein_coding synonymous_variant LOW 207C>T Asp69Asp
M0022235 MIFKINMO_00009 12975 4 Skin 0.67 protein_coding synonymous_variant LOW 150A>C Ala50Ala
M0022236 MIFKINMO_00009 12984 4 Skin 0.67 protein_coding synonymous_variant LOW 141A>C Thr47Thr
M0022237 MIFKINMO_00009 12990 4 Skin 0.67 protein_coding synonymous_variant LOW 135T>C His45His
M0022238 MIFKINMO_00009 12993 4 Skin 0.67 protein_coding synonymous_variant LOW 132T>C Gly44Gly
M0022239 MIFKINMO_00009 12997 4 Skin 0.67 protein_coding missense_variant MODERATE 128C>A Ala43Asp
M0022240 MIFKINMO_00009 12998 4 Skin 0.67 protein_coding missense_variant MODERATE 127G>C Ala43Pro
M0022241 MIFKINMO_00009 13002 4 Skin 0.67 protein_coding synonymous_variant LOW 123T>C Arg41Arg
M0022242 MIFKINMO_00009 13053 4 Skin 0.67 protein_coding missense_variant MODERATE 72A>C Lys24Asn
M0022243 MIFKINMO_00009 13065 4 Skin 0.67 protein_coding synonymous_variant LOW 60C>T Ala20Ala
M0022244 MIFKINMO_00009 13160 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -36T>C None
M0022245 MIFKINMO_00009 12603 3 Skin 0.50 protein_coding synonymous_variant LOW 522T>C Arg174Arg
M0022246 MIFKINMO_00009 12668 3 Skin 0.50 protein_coding missense_variant MODERATE 457T>C Cys153Arg
M0022247 MIFKINMO_00009 13033 3 Skin 0.50 protein_coding missense_variant MODERATE 92G>A Gly31Asp
M0022248 MIFKINMO_00009 13046 3 Skin 0.50 protein_coding missense_variant MODERATE 79G>C Val27Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term