Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2008
  Reference Plasmid   1111525849736908_bin.20__k141_111613
  Reference Plasmid Size   3649
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022249 EPOKLLAN_00001 593 12 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -266C>T None
M0022250 EPOKLLAN_00001 998 9 Skin 0.60 protein_coding missense_variant MODERATE 140A>G Asn47Ser
M0022251 EPOKLLAN_00003 2859 9 Skin 0.60 protein_coding synonymous_variant LOW 726T>C Thr242Thr
M0022252 EPOKLLAN_00002 1159 3 Skin 0.20 protein_coding synonymous_variant LOW 87A>C Val29Val
M0022253 EPOKLLAN_00002 1202 3 Skin 0.20 protein_coding synonymous_variant LOW 130T>C Leu44Leu
M0022254 EPOKLLAN_00001 3082 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *1984C>T None
M0022255 EPOKLLAN_00001 3178 5 Skin 0.33 protein_coding downstream_gene_variant MODIFIER *2080C>T None
M0022256 EPOKLLAN_00001 3208 5 Skin 0.33 protein_coding downstream_gene_variant MODIFIER *2110T>C None
M0022257 EPOKLLAN_00001 3220 5 Skin 0.33 protein_coding downstream_gene_variant MODIFIER *2122T>C None
M0022258 EPOKLLAN_00001 3238 4 Skin 0.27 protein_coding downstream_gene_variant MODIFIER *2140T>C None
M0022259 EPOKLLAN_00001 3292 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *2194C>T None
M0022260 EPOKLLAN_00001 3313 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *2215A>G None
M0022261 EPOKLLAN_00001 3337 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *2239T>C None
M0022262 EPOKLLAN_00001 3366 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *2268A>G None
M0022263 EPOKLLAN_00001 3394 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *2296A>G None
M0022264 EPOKLLAN_00001 3499 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *2401A>G None
M0022265 EPOKLLAN_00002 1867 5 Skin 0.33 protein_coding synonymous_variant LOW 795C>A Val265Val
M0022266 EPOKLLAN_00002 1501 3 Skin 0.20 protein_coding synonymous_variant LOW 429T>C Ala143Ala
M0022267 EPOKLLAN_00002 1531 3 Skin 0.20 protein_coding synonymous_variant LOW 459C>T Ile153Ile
M0022268 EPOKLLAN_00002 1648 5 Skin 0.33 protein_coding synonymous_variant LOW 576A>G Ala192Ala
M0022269 EPOKLLAN_00002 1778 3 Skin 0.20 protein_coding synonymous_variant LOW 706T>C Leu236Leu
M0022270 EPOKLLAN_00003 2238 4 Skin 0.27 protein_coding synonymous_variant LOW 105T>C Val35Val
M0022271 EPOKLLAN_00003 2617 3 Skin 0.20 protein_coding synonymous_variant LOW 484T>C Leu162Leu
M0022272 EPOKLLAN_00003 2637 3 Skin 0.20 protein_coding synonymous_variant LOW 504C>T Asn168Asn
M0022273 EPOKLLAN_00002 1630 3 Skin 0.20 protein_coding synonymous_variant LOW 558A>G Arg186Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term