Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2015
  Reference Plasmid   1111525849736979_bin.18__k141_65249
  Reference Plasmid Size   10226
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022573 JNEKEMOJ_00006 4802 7 Skin 0.32 protein_coding missense_variant MODERATE 312T>G Asp104Glu
M0022574 JNEKEMOJ_00006 4834 7 Skin 0.32 protein_coding missense_variant MODERATE 280A>T Thr94Ser
M0022575 JNEKEMOJ_00006 4862 7 Skin 0.32 protein_coding synonymous_variant LOW 252T>C Ile84Ile
M0022576 JNEKEMOJ_00006 5004 6 Skin 0.27 protein_coding missense_variant MODERATE 110G>C Ser37Thr
M0022577 JNEKEMOJ_00006 5087 6 Skin 0.27 protein_coding synonymous_variant LOW 27G>A Gln9Gln
M0022578 JNEKEMOJ_00007 5196 6 Skin 0.27 protein_coding synonymous_variant LOW 174A>G Arg58Arg
M0022579 JNEKEMOJ_00007 5213 6 Skin 0.27 protein_coding missense_variant MODERATE 157C>G Pro53Ala
M0022580 JNEKEMOJ_00007 5250 6 Skin 0.27 protein_coding missense_variant MODERATE 120C>G Asp40Glu
M0022581 JNEKEMOJ_00007 5254 3 Skin 0.14 protein_coding missense_variant MODERATE 116T>G Phe39Cys
M0022582 JNEKEMOJ_00007 5271 6 Skin 0.27 protein_coding synonymous_variant LOW 99C>G Ala33Ala
M0022583 JNEKEMOJ_00007 5295 6 Skin 0.27 protein_coding synonymous_variant LOW 75G>A Lys25Lys
M0022584 JNEKEMOJ_00007 5346 6 Skin 0.27 protein_coding synonymous_variant LOW 24G>C Ser8Ser
M0022585 JNEKEMOJ_00008 5387 6 Skin 0.27 protein_coding missense_variant MODERATE 244A>C Met82Leu
M0022586 JNEKEMOJ_00008 5409 6 Skin 0.27 protein_coding synonymous_variant LOW 222C>T Val74Val
M0022587 JNEKEMOJ_00008 5427 6 Skin 0.27 protein_coding synonymous_variant LOW 204C>A Arg68Arg
M0022588 JNEKEMOJ_00008 5451 6 Skin 0.27 protein_coding synonymous_variant LOW 180C>A Arg60Arg
M0022589 JNEKEMOJ_00008 5532 8 Skin 0.36 protein_coding synonymous_variant LOW 99C>G Gly33Gly
M0022590 JNEKEMOJ_00008 5553 8 Skin 0.36 protein_coding synonymous_variant LOW 78G>C Val26Val
M0022591 JNEKEMOJ_00008 5559 8 Skin 0.36 protein_coding missense_variant MODERATE 72G>C Glu24Asp
M0022592 JNEKEMOJ_00008 5571 8 Skin 0.36 protein_coding synonymous_variant LOW 60C>T Asn20Asn
M0022593 JNEKEMOJ_00006 5676 4 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -563A>G None
M0022594 JNEKEMOJ_00006 5766 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -653G>A None
M0022595 JNEKEMOJ_00006 5770 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -657C>G None
M0022596 JNEKEMOJ_00009 5986 7 Skin 0.32 protein_coding synonymous_variant LOW 30G>A Val10Val
M0022597 JNEKEMOJ_00009 5997 6 Skin 0.27 protein_coding missense_variant MODERATE 41A>C Glu14Ala
M0022598 JNEKEMOJ_00009 6217 7 Skin 0.32 protein_coding missense_variant MODERATE 261C>G His87Gln
M0022599 JNEKEMOJ_00006 6496 8 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -1383T>C None
M0022600 JNEKEMOJ_00010 6686 9 Skin 0.41 protein_coding synonymous_variant LOW 174C>T Arg58Arg
M0022601 JNEKEMOJ_00006 7458 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -2345G>A None
M0022602 JNEKEMOJ_00012 7492 3 Skin 0.14 protein_coding missense_variant MODERATE 19A>G Ser7Gly
M0022603 JNEKEMOJ_00012 7602 9 Skin 0.41 protein_coding synonymous_variant LOW 129T>C Tyr43Tyr
M0022604 JNEKEMOJ_00012 8071 3 Skin 0.14 protein_coding missense_variant MODERATE 598G>A Val200Met
M0022605 JNEKEMOJ_00006 4689 5 Skin 0.23 protein_coding missense_variant MODERATE 425T>C Val142Ala
M0022606 JNEKEMOJ_00006 4739 5 Skin 0.23 protein_coding synonymous_variant LOW 375T>C Ala125Ala
M0022607 JNEKEMOJ_00006 4948 4 Skin 0.18 protein_coding missense_variant MODERATE 166C>T His56Tyr
M0022608 JNEKEMOJ_00006 6430 4 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1317T>C None
M0022609 JNEKEMOJ_00010 6788 4 Skin 0.18 protein_coding synonymous_variant LOW 276C>T Gly92Gly
M0022610 JNEKEMOJ_00011 7035 3 Skin 0.14 protein_coding missense_variant MODERATE 158G>C Gly53Ala
M0022611 JNEKEMOJ_00011 7057 3 Skin 0.14 protein_coding synonymous_variant LOW 180A>G Arg60Arg
M0022612 JNEKEMOJ_00011 7084 3 Skin 0.14 protein_coding synonymous_variant LOW 207T>C Val69Val
M0022613 JNEKEMOJ_00011 7111 3 Skin 0.14 protein_coding synonymous_variant LOW 234C>A Val78Val
M0022614 JNEKEMOJ_00006 4757 3 Skin 0.14 protein_coding synonymous_variant LOW 357T>C His119His
M0022615 JNEKEMOJ_00006 4763 3 Skin 0.14 protein_coding synonymous_variant LOW 351A>C Ala117Ala
M0022616 JNEKEMOJ_00010 6814 5 Skin 0.23 protein_coding missense_variant MODERATE 302G>A Gly101Asp
M0022617 JNEKEMOJ_00006 7343 8 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -2230G>A None
M0022618 JNEKEMOJ_00006 7363 11 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2250C>T None
M0022619 JNEKEMOJ_00010 6875 3 Skin 0.14 protein_coding synonymous_variant LOW 363A>G Pro121Pro
M0022620 JNEKEMOJ_00011 7034 3 Skin 0.14 protein_coding missense_variant MODERATE 157G>A Gly53Arg
M0022621 JNEKEMOJ_00012 7514 3 Skin 0.14 protein_coding missense_variant MODERATE 41T>C Val14Ala
M0022622 JNEKEMOJ_00011 6940 3 Skin 0.14 protein_coding synonymous_variant LOW 63T>C Gly21Gly
M0022623 JNEKEMOJ_00011 6949 3 Skin 0.14 protein_coding synonymous_variant LOW 72T>C Val24Val
M0022624 JNEKEMOJ_00012 7755 3 Skin 0.14 protein_coding synonymous_variant LOW 282C>T Asp94Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term