Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2016
  Reference Plasmid   1111525849737037_bin.1__k141_160066
  Reference Plasmid Size   15109
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022627 CBPKCFDM_00004 2394 6 Skin 1.00 protein_coding missense_variant MODERATE 443A>G Asp148Gly
M0022628 CBPKCFDM_00004 2432 4 Skin 0.67 protein_coding synonymous_variant LOW 405T>C Val135Val
M0022629 CBPKCFDM_00004 2448 4 Skin 0.67 protein_coding missense_variant MODERATE 389A>G Glu130Gly
M0022630 CBPKCFDM_00004 2549 3 Skin 0.50 protein_coding synonymous_variant LOW 288G>T Ala96Ala
M0022631 CBPKCFDM_00004 2571 3 Skin 0.50 protein_coding missense_variant MODERATE 266T>C Val89Ala
M0022632 CBPKCFDM_00004 2591 3 Skin 0.50 protein_coding synonymous_variant LOW 246C>G Val82Val
M0022633 CBPKCFDM_00004 2600 3 Skin 0.50 protein_coding synonymous_variant LOW 237T>C Phe79Phe
M0022634 CBPKCFDM_00004 2618 4 Skin 0.67 protein_coding synonymous_variant LOW 219T>C Val73Val
M0022635 CBPKCFDM_00004 2624 3 Skin 0.50 protein_coding synonymous_variant LOW 213C>T Cys71Cys
M0022636 CBPKCFDM_00004 2633 3 Skin 0.50 protein_coding synonymous_variant LOW 204T>G Gly68Gly
M0022637 CBPKCFDM_00004 2663 3 Skin 0.50 protein_coding synonymous_variant LOW 174G>C Ala58Ala
M0022638 CBPKCFDM_00004 2672 3 Skin 0.50 protein_coding synonymous_variant LOW 165A>G Ala55Ala
M0022639 CBPKCFDM_00004 2723 3 Skin 0.50 protein_coding synonymous_variant LOW 114A>G Gln38Gln
M0022640 CBPKCFDM_00006 3599 4 Skin 0.67 protein_coding synonymous_variant LOW 534G>C Ala178Ala
M0022641 CBPKCFDM_00006 3602 4 Skin 0.67 protein_coding synonymous_variant LOW 531T>C Ser177Ser
M0022642 CBPKCFDM_00006 3638 4 Skin 0.67 protein_coding synonymous_variant LOW 495T>C Phe165Phe
M0022643 CBPKCFDM_00006 3692 4 Skin 0.67 protein_coding synonymous_variant LOW 441C>T Ser147Ser
M0022644 CBPKCFDM_00006 3693 4 Skin 0.67 protein_coding missense_variant MODERATE 440G>A Ser147Asn
M0022645 CBPKCFDM_00006 3743 4 Skin 0.67 protein_coding synonymous_variant LOW 390T>C Gly130Gly
M0022646 CBPKCFDM_00006 4037 3 Skin 0.50 protein_coding synonymous_variant LOW 96T>G Leu32Leu
M0022647 CBPKCFDM_00006 4128 5 Skin 0.83 protein_coding missense_variant MODERATE 5T>C Ile2Thr
M0022648 CBPKCFDM_00007 4241 3 Skin 0.50 protein_coding synonymous_variant LOW 1821A>G Glu607Glu
M0022649 CBPKCFDM_00007 4532 4 Skin 0.67 protein_coding missense_variant MODERATE 1530A>C Glu510Asp
M0022650 CBPKCFDM_00007 4772 4 Skin 0.67 protein_coding synonymous_variant LOW 1290G>C Gly430Gly
M0022651 CBPKCFDM_00007 5039 3 Skin 0.50 protein_coding synonymous_variant LOW 1023C>G Leu341Leu
M0022652 CBPKCFDM_00001 525 3 Skin 0.50 protein_coding synonymous_variant LOW 516T>C Ser172Ser
M0022653 CBPKCFDM_00001 570 3 Skin 0.50 protein_coding synonymous_variant LOW 561T>C Tyr187Tyr
M0022654 CBPKCFDM_00001 573 3 Skin 0.50 protein_coding synonymous_variant LOW 564C>G Val188Val
M0022655 CBPKCFDM_00001 579 3 Skin 0.50 protein_coding synonymous_variant LOW 570T>G Arg190Arg
M0022656 CBPKCFDM_00001 861 3 Skin 0.50 protein_coding synonymous_variant LOW 852A>G Ala284Ala
M0022657 CBPKCFDM_00004 3307 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -471C>T None
M0022658 CBPKCFDM_00004 3319 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -483C>T None
M0022659 CBPKCFDM_00004 3333 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -497G>C None
M0022660 CBPKCFDM_00004 3365 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -529G>A None
M0022661 CBPKCFDM_00006 3560 4 Skin 0.67 protein_coding synonymous_variant LOW 573C>A Ile191Ile
M0022662 CBPKCFDM_00006 3562 3 Skin 0.50 protein_coding missense_variant MODERATE 571A>G Ile191Val
M0022663 CBPKCFDM_00006 3566 3 Skin 0.50 protein_coding synonymous_variant LOW 567C>T Gly189Gly
M0022664 CBPKCFDM_00006 3734 3 Skin 0.50 protein_coding synonymous_variant LOW 399C>G Gly133Gly
M0022665 CBPKCFDM_00001 801 3 Skin 0.50 protein_coding synonymous_variant LOW 792T>C Ile264Ile
M0022666 CBPKCFDM_00003 1661 3 Skin 0.50 protein_coding synonymous_variant LOW 54G>T Leu18Leu
M0022667 CBPKCFDM_00003 1667 3 Skin 0.50 protein_coding synonymous_variant LOW 60T>C Leu20Leu
M0022668 CBPKCFDM_00006 3427 3 Skin 0.50 protein_coding missense_variant MODERATE 706G>T Ala236Ser
M0022669 CBPKCFDM_00007 4508 3 Skin 0.50 protein_coding synonymous_variant LOW 1554C>G Ala518Ala
M0022670 CBPKCFDM_00007 4546 3 Skin 0.50 protein_coding missense_variant MODERATE 1516C>G Pro506Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
CBPKCFDM_00012 VFG011430 LPS 85.9 3.5e-31 1 78 1.0 1 Immune modulation acyl carrier protein experiment
CBPKCFDM_00012 VFG011430 LPS 85.9 2.6e-30 1 78 1.0 1 Immune modulation acyl carrier protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term