Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2025
  Reference Plasmid   1111525849737158_bin.10__k141_107604
  Reference Plasmid Size   11987
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022972 CBKCNNIF_00001 33 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -12G>A None
M0022973 CBKCNNIF_00003 1663 3 Skin 0.33 protein_coding missense_variant MODERATE 451A>G Ser151Gly
M0022974 CBKCNNIF_00003 1664 3 Skin 0.33 protein_coding missense_variant MODERATE 452G>C Ser151Thr
M0022975 CBKCNNIF_00005 2878 3 Skin 0.33 protein_coding synonymous_variant LOW 150T>C Gly50Gly
M0022976 CBKCNNIF_00009 6621 3 Skin 0.33 protein_coding synonymous_variant LOW 231T>C Ile77Ile
M0022977 CBKCNNIF_00009 6942 3 Skin 0.33 protein_coding synonymous_variant LOW 552A>G Glu184Glu
M0022978 CBKCNNIF_00009 7375 3 Skin 0.33 protein_coding synonymous_variant LOW 985T>C Leu329Leu
M0022979 CBKCNNIF_00010 7998 4 Skin 0.44 protein_coding synonymous_variant LOW 363C>A Ala121Ala
M0022980 CBKCNNIF_00010 8491 4 Skin 0.44 protein_coding missense_variant MODERATE 856A>G Asn286Asp
M0022981 CBKCNNIF_00010 8556 4 Skin 0.44 protein_coding missense_variant MODERATE 921C>A Asp307Glu
M0022982 CBKCNNIF_00010 8601 4 Skin 0.44 protein_coding synonymous_variant LOW 966A>G Leu322Leu
M0022983 CBKCNNIF_00011 9698 4 Skin 0.44 protein_coding synonymous_variant LOW 594C>G Gly198Gly
M0022984 CBKCNNIF_00011 9702 4 Skin 0.44 protein_coding missense_variant MODERATE 598G>A Val200Ile
M0022985 CBKCNNIF_00011 9731 4 Skin 0.44 protein_coding synonymous_variant LOW 627G>A Glu209Glu
M0022986 CBKCNNIF_00011 9734 4 Skin 0.44 protein_coding synonymous_variant LOW 630T>C Ile210Ile
M0022987 CBKCNNIF_00011 10318 4 Skin 0.44 protein_coding missense_variant MODERATE 1214T>C Leu405Pro
M0022988 CBKCNNIF_00008 10916 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -4671A>G None
M0022989 CBKCNNIF_00012 11720 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -123C>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term