Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2026
  Reference Plasmid   1111525849737158_bin.10__k141_17829
  Reference Plasmid Size   35447
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0022990 KINADBHJ_00005 5954 3 Skin 0.21 protein_coding synonymous_variant LOW 2818T>C Leu940Leu
M0022991 KINADBHJ_00005 6835 3 Skin 0.21 protein_coding synonymous_variant LOW 3699T>C His1233His
M0022992 KINADBHJ_00006 7260 3 Skin 0.21 protein_coding synonymous_variant LOW 207A>G Glu69Glu
M0022993 KINADBHJ_00015 18698 4 Skin 0.29 protein_coding synonymous_variant LOW 394T>C Leu132Leu
M0022994 KINADBHJ_00015 18750 3 Skin 0.21 protein_coding synonymous_variant LOW 342G>A Ala114Ala
M0022995 KINADBHJ_00015 18873 4 Skin 0.29 protein_coding synonymous_variant LOW 219G>C Leu73Leu
M0022996 KINADBHJ_00016 20260 3 Skin 0.21 protein_coding synonymous_variant LOW 795C>T Ala265Ala
M0022997 KINADBHJ_00016 20665 4 Skin 0.29 protein_coding synonymous_variant LOW 1200A>G Gly400Gly
M0022998 KINADBHJ_00016 21070 3 Skin 0.21 protein_coding synonymous_variant LOW 1605G>A Pro535Pro
M0022999 KINADBHJ_00016 21085 3 Skin 0.21 protein_coding synonymous_variant LOW 1620C>T Ser540Ser
M0023000 KINADBHJ_00016 21274 3 Skin 0.21 protein_coding synonymous_variant LOW 1809C>T Gly603Gly
M0023001 KINADBHJ_00016 21426 3 Skin 0.21 protein_coding missense_variant MODERATE 1961A>C Asn654Thr
M0023002 KINADBHJ_00016 21673 4 Skin 0.29 protein_coding synonymous_variant LOW 2208T>C Arg736Arg
M0023003 KINADBHJ_00017 21805 4 Skin 0.29 protein_coding missense_variant MODERATE 37G>A Gly13Ser
M0023004 KINADBHJ_00017 21817 4 Skin 0.29 protein_coding missense_variant MODERATE 49C>T Leu17Phe
M0023005 KINADBHJ_00017 21891 4 Skin 0.29 protein_coding synonymous_variant LOW 123C>T Arg41Arg
M0023006 KINADBHJ_00015 22005 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2914G>T None
M0023007 KINADBHJ_00015 22033 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2942C>T None
M0023008 KINADBHJ_00015 22074 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2983G>A None
M0023009 KINADBHJ_00018 22149 3 Skin 0.21 protein_coding synonymous_variant LOW 1086A>G Val362Val
M0023010 KINADBHJ_00021 24818 5 Skin 0.36 protein_coding synonymous_variant LOW 1248G>C Gly416Gly
M0023011 KINADBHJ_00021 24822 5 Skin 0.36 protein_coding missense_variant MODERATE 1244G>C Cys415Ser
M0023012 KINADBHJ_00022 26748 3 Skin 0.21 protein_coding synonymous_variant LOW 1005C>T Gly335Gly
M0023013 KINADBHJ_00022 26775 3 Skin 0.21 protein_coding synonymous_variant LOW 978C>T Ser326Ser
M0023014 KINADBHJ_00011 13971 4 Skin 0.29 protein_coding synonymous_variant LOW 1335T>C His445His
M0023015 KINADBHJ_00011 14799 3 Skin 0.21 protein_coding synonymous_variant LOW 507A>G Ser169Ser
M0023016 KINADBHJ_00012 15847 4 Skin 0.29 protein_coding missense_variant MODERATE 329G>A Gly110Asp
M0023017 KINADBHJ_00013 17154 3 Skin 0.21 protein_coding synonymous_variant LOW 813C>T Arg271Arg
M0023018 KINADBHJ_00014 17680 3 Skin 0.21 protein_coding synonymous_variant LOW 504G>C Val168Val
M0023019 KINADBHJ_00014 17743 3 Skin 0.21 protein_coding synonymous_variant LOW 567G>A Glu189Glu
M0023020 KINADBHJ_00015 18442 3 Skin 0.21 protein_coding missense_variant MODERATE 650T>C Met217Thr
M0023021 KINADBHJ_00023 27852 3 Skin 0.21 protein_coding missense_variant MODERATE 884G>C Arg295Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term