Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2027
  Reference Plasmid   1111525849737158_bin.10__k141_284781
  Reference Plasmid Size   9645
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023022 FLNOLIFP_00005 7558 3 Skin 0.43 protein_coding synonymous_variant LOW 879T>C Asp293Asp
M0023023 FLNOLIFP_00001 1657 3 Skin 0.43 protein_coding synonymous_variant LOW 201T>C Ala67Ala
M0023024 FLNOLIFP_00001 1660 3 Skin 0.43 protein_coding synonymous_variant LOW 198G>C Ala66Ala
M0023025 FLNOLIFP_00001 1783 4 Skin 0.57 protein_coding synonymous_variant LOW 75T>C Leu25Leu
M0023026 FLNOLIFP_00001 1786 3 Skin 0.43 protein_coding synonymous_variant LOW 72A>G Gly24Gly
M0023027 FLNOLIFP_00001 1810 4 Skin 0.57 protein_coding synonymous_variant LOW 48C>T Leu16Leu
M0023028 FLNOLIFP_00002 3364 3 Skin 0.43 protein_coding synonymous_variant LOW 399G>A Ala133Ala
M0023029 FLNOLIFP_00002 3379 3 Skin 0.43 protein_coding synonymous_variant LOW 384T>G Arg128Arg
M0023030 FLNOLIFP_00002 3382 3 Skin 0.43 protein_coding synonymous_variant LOW 381G>A Ala127Ala
M0023031 FLNOLIFP_00003 4620 3 Skin 0.43 protein_coding synonymous_variant LOW 381T>C Thr127Thr
M0023032 FLNOLIFP_00004 513 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4846T>G None
M0023033 FLNOLIFP_00001 1081 3 Skin 0.43 protein_coding synonymous_variant LOW 777A>G Ala259Ala
M0023034 FLNOLIFP_00002 2958 3 Skin 0.43 protein_coding missense_variant MODERATE 805T>C Ser269Pro
M0023035 FLNOLIFP_00002 3676 3 Skin 0.43 protein_coding synonymous_variant LOW 87C>G Thr29Thr
M0023036 FLNOLIFP_00002 3694 3 Skin 0.43 protein_coding synonymous_variant LOW 69G>C Ala23Ala
M0023037 FLNOLIFP_00003 4530 3 Skin 0.43 protein_coding synonymous_variant LOW 471G>C Ala157Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term