Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2028
  Reference Plasmid   1111525849737158_bin.10__k141_289112
  Reference Plasmid Size   11136
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023038 HADIBJDG_00007 6468 3 Skin 0.50 protein_coding synonymous_variant LOW 1299C>T Tyr433Tyr
M0023039 HADIBJDG_00007 6483 3 Skin 0.50 protein_coding synonymous_variant LOW 1284G>C Thr428Thr
M0023040 HADIBJDG_00007 6491 3 Skin 0.50 protein_coding missense_variant MODERATE 1276A>C Met426Leu
M0023041 HADIBJDG_00007 6510 3 Skin 0.50 protein_coding synonymous_variant LOW 1257T>C Tyr419Tyr
M0023042 HADIBJDG_00007 6516 3 Skin 0.50 protein_coding synonymous_variant LOW 1251C>T Ala417Ala
M0023043 HADIBJDG_00007 6521 3 Skin 0.50 protein_coding missense_variant MODERATE 1246G>T Ala416Ser
M0023044 HADIBJDG_00007 6522 3 Skin 0.50 protein_coding synonymous_variant LOW 1245G>T Leu415Leu
M0023045 HADIBJDG_00007 6525 3 Skin 0.50 protein_coding synonymous_variant LOW 1242A>C Ala414Ala
M0023046 HADIBJDG_00007 6528 3 Skin 0.50 protein_coding synonymous_variant LOW 1239G>C Gly413Gly
M0023047 HADIBJDG_00007 6570 3 Skin 0.50 protein_coding synonymous_variant LOW 1197G>C Pro399Pro
M0023048 HADIBJDG_00007 6572 3 Skin 0.50 protein_coding missense_variant MODERATE 1195C>G Pro399Ala
M0023049 HADIBJDG_00007 6573 3 Skin 0.50 protein_coding synonymous_variant LOW 1194A>G Gln398Gln
M0023050 HADIBJDG_00007 6590 3 Skin 0.50 protein_coding missense_variant MODERATE 1177A>G Ile393Val
M0023051 HADIBJDG_00007 6630 3 Skin 0.50 protein_coding synonymous_variant LOW 1137G>C Pro379Pro
M0023052 HADIBJDG_00007 6717 3 Skin 0.50 protein_coding synonymous_variant LOW 1050T>C Phe350Phe
M0023053 HADIBJDG_00007 7083 3 Skin 0.50 protein_coding synonymous_variant LOW 684T>C Leu228Leu
M0023054 HADIBJDG_00007 7294 3 Skin 0.50 protein_coding missense_variant MODERATE 473G>A Arg158Gln
M0023055 HADIBJDG_00008 8092 3 Skin 0.50 protein_coding missense_variant MODERATE 67A>G Thr23Ala
M0023056 HADIBJDG_00009 8749 3 Skin 0.50 protein_coding missense_variant MODERATE 320A>G Gln107Arg
M0023057 HADIBJDG_00004 3796 5 Skin 0.83 protein_coding synonymous_variant LOW 534T>C Asp178Asp
M0023058 HADIBJDG_00004 3930 3 Skin 0.50 protein_coding synonymous_variant LOW 400C>T Leu134Leu
M0023059 HADIBJDG_00004 3957 3 Skin 0.50 protein_coding missense_variant MODERATE 373G>A Ala125Thr
M0023060 HADIBJDG_00004 4261 3 Skin 0.50 protein_coding missense_variant MODERATE 69G>C Leu23Phe
M0023061 HADIBJDG_00004 4263 3 Skin 0.50 protein_coding synonymous_variant LOW 67T>C Leu23Leu
M0023062 HADIBJDG_00004 4264 3 Skin 0.50 protein_coding synonymous_variant LOW 66G>C Ala22Ala
M0023063 HADIBJDG_00004 4273 3 Skin 0.50 protein_coding synonymous_variant LOW 57G>C Arg19Arg
M0023064 HADIBJDG_00004 4287 5 Skin 0.83 protein_coding missense_variant MODERATE 43T>C Ser15Pro
M0023065 HADIBJDG_00004 4308 5 Skin 0.83 protein_coding missense_variant MODERATE 22A>G Asn8Asp
M0023066 HADIBJDG_00005 4334 3 Skin 0.50 protein_coding missense_variant MODERATE 829A>G Ser277Gly
M0023067 HADIBJDG_00005 4503 3 Skin 0.50 protein_coding synonymous_variant LOW 660T>C Asp220Asp
M0023068 HADIBJDG_00002 5166 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -3837A>G None
M0023069 HADIBJDG_00006 5735 3 Skin 0.50 protein_coding synonymous_variant LOW 414T>C Thr138Thr
M0023070 HADIBJDG_00007 6189 3 Skin 0.50 protein_coding synonymous_variant LOW 1578G>C Ser526Ser
M0023071 HADIBJDG_00007 6252 3 Skin 0.50 protein_coding synonymous_variant LOW 1515C>G Arg505Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term