Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2034
  Reference Plasmid   1111525849737158_bin.20__k141_240817
  Reference Plasmid Size   16606
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023098 JAJFNBAD_00012 13800 3 Skin 0.50 protein_coding missense_variant MODERATE 384C>A Asp128Glu
M0023099 JAJFNBAD_00008 14415 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4950A>C None
M0023100 JAJFNBAD_00008 14417 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4952A>G None
M0023101 JAJFNBAD_00008 14419 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4954A>G None
M0023102 JAJFNBAD_00008 14422 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4957G>A None
M0023103 JAJFNBAD_00008 14423 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4958G>A None
M0023104 JAJFNBAD_00008 14427 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4962T>G None
M0023105 JAJFNBAD_00008 14438 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4973G>A None
M0023106 JAJFNBAD_00008 14444 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4979C>T None
M0023107 JAJFNBAD_00009 14469 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4120A>G None
M0023108 JAJFNBAD_00009 14500 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4151G>A None
M0023109 JAJFNBAD_00009 14503 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4154T>G None
M0023110 JAJFNBAD_00009 14549 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4200A>G None
M0023111 JAJFNBAD_00009 14551 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4202A>G None
M0023112 JAJFNBAD_00009 14586 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4237G>A None
M0023113 JAJFNBAD_00009 14592 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4243G>T None
M0023114 JAJFNBAD_00013 14774 3 Skin 0.50 protein_coding synonymous_variant LOW 168A>C Ile56Ile
M0023115 JAJFNBAD_00013 14792 3 Skin 0.50 protein_coding synonymous_variant LOW 186A>C Ile62Ile
M0023116 JAJFNBAD_00013 14882 3 Skin 0.50 protein_coding synonymous_variant LOW 276A>G Ser92Ser
M0023117 JAJFNBAD_00013 14957 3 Skin 0.50 protein_coding synonymous_variant LOW 351T>C Asn117Asn
M0023118 JAJFNBAD_00013 15080 3 Skin 0.50 protein_coding synonymous_variant LOW 474G>A Glu158Glu
M0023119 JAJFNBAD_00013 15329 3 Skin 0.50 protein_coding synonymous_variant LOW 723T>C Ser241Ser
M0023120 JAJFNBAD_00013 15337 3 Skin 0.50 protein_coding missense_variant MODERATE 731A>G Lys244Arg
M0023121 JAJFNBAD_00013 15578 3 Skin 0.50 protein_coding synonymous_variant LOW 972C>T Asn324Asn
M0023122 JAJFNBAD_00014 16031 3 Skin 0.50 protein_coding synonymous_variant LOW 270C>T Asn90Asn
M0023123 JAJFNBAD_00014 16296 3 Skin 0.50 protein_coding missense_variant MODERATE 535A>G Ser179Gly
M0023124 JAJFNBAD_00014 16322 3 Skin 0.50 protein_coding synonymous_variant LOW 561T>C His187His
M0023125 JAJFNBAD_00012 16541 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2358T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term