Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2036
  Reference Plasmid   1111525849737158_bin.20__k141_94431
  Reference Plasmid Size   25699
  Reference Plasmid GC Content   0.59
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023133 JINHOBKD_00001 192 3 Skin 0.38 protein_coding missense_variant MODERATE 27A>C Lys9Asn
M0023134 JINHOBKD_00001 229 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -11A>C None
M0023135 JINHOBKD_00001 303 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -85G>A None
M0023136 JINHOBKD_00001 324 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -106G>C None
M0023137 JINHOBKD_00001 329 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -111G>A None
M0023138 JINHOBKD_00001 342 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -124A>G None
M0023139 JINHOBKD_00001 1246 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -1028T>C None
M0023140 JINHOBKD_00001 1392 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -1174T>C None
M0023141 JINHOBKD_00004 2051 3 Skin 0.38 protein_coding synonymous_variant LOW 72G>C Gly24Gly
M0023142 JINHOBKD_00004 2066 3 Skin 0.38 protein_coding synonymous_variant LOW 87A>G Leu29Leu
M0023143 JINHOBKD_00004 2182 3 Skin 0.38 protein_coding missense_variant MODERATE 203A>C Gln68Pro
M0023144 JINHOBKD_00004 2519 3 Skin 0.38 protein_coding synonymous_variant LOW 540C>T Ala180Ala
M0023145 JINHOBKD_00004 2534 3 Skin 0.38 protein_coding synonymous_variant LOW 555A>C Leu185Leu
M0023146 JINHOBKD_00004 2540 3 Skin 0.38 protein_coding synonymous_variant LOW 561T>C Gly187Gly
M0023147 JINHOBKD_00004 2699 3 Skin 0.38 protein_coding synonymous_variant LOW 720T>C Phe240Phe
M0023148 JINHOBKD_00004 2882 3 Skin 0.38 protein_coding synonymous_variant LOW 903G>A Thr301Thr
M0023149 JINHOBKD_00004 3167 3 Skin 0.38 protein_coding synonymous_variant LOW 1188T>C Val396Val
M0023150 JINHOBKD_00004 3191 3 Skin 0.38 protein_coding synonymous_variant LOW 1212C>A Ala404Ala
M0023151 JINHOBKD_00004 3266 3 Skin 0.38 protein_coding synonymous_variant LOW 1287C>G Ala429Ala
M0023152 JINHOBKD_00012 12418 3 Skin 0.38 protein_coding synonymous_variant LOW 780C>T Gly260Gly
M0023153 JINHOBKD_00012 12739 3 Skin 0.38 protein_coding synonymous_variant LOW 1101C>T Ala367Ala
M0023154 JINHOBKD_00013 12771 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -64A>G None
M0023155 JINHOBKD_00013 12964 3 Skin 0.38 protein_coding missense_variant MODERATE 130C>T His44Tyr
M0023156 JINHOBKD_00013 12975 3 Skin 0.38 protein_coding synonymous_variant LOW 141A>G Pro47Pro
M0023157 JINHOBKD_00013 12984 3 Skin 0.38 protein_coding synonymous_variant LOW 150C>T Tyr50Tyr
M0023158 JINHOBKD_00013 13038 3 Skin 0.38 protein_coding synonymous_variant LOW 204C>T Ile68Ile
M0023159 JINHOBKD_00013 13044 3 Skin 0.38 protein_coding synonymous_variant LOW 210A>C Ala70Ala
M0023160 JINHOBKD_00013 13065 3 Skin 0.38 protein_coding synonymous_variant LOW 231C>T His77His
M0023161 JINHOBKD_00013 13126 3 Skin 0.38 protein_coding missense_variant MODERATE 292A>C Met98Leu
M0023162 JINHOBKD_00013 13257 3 Skin 0.38 protein_coding synonymous_variant LOW 423T>G Ser141Ser
M0023163 JINHOBKD_00016 15377 3 Skin 0.38 protein_coding synonymous_variant LOW 1017A>G Glu339Glu
M0023164 JINHOBKD_00016 15407 3 Skin 0.38 protein_coding synonymous_variant LOW 987T>C Thr329Thr
M0023165 JINHOBKD_00016 15438 3 Skin 0.38 protein_coding missense_variant MODERATE 956T>C Met319Thr
M0023166 JINHOBKD_00016 15449 3 Skin 0.38 protein_coding missense_variant MODERATE 945G>C Glu315Asp
M0023167 JINHOBKD_00016 15593 3 Skin 0.38 protein_coding synonymous_variant LOW 801T>G Thr267Thr
M0023168 JINHOBKD_00016 15600 3 Skin 0.38 protein_coding missense_variant MODERATE 794C>G Ala265Gly
M0023169 JINHOBKD_00016 15674 3 Skin 0.38 protein_coding synonymous_variant LOW 720G>A Gly240Gly
M0023170 JINHOBKD_00016 15854 3 Skin 0.38 protein_coding synonymous_variant LOW 540G>T Leu180Leu
M0023171 JINHOBKD_00016 15986 3 Skin 0.38 protein_coding synonymous_variant LOW 408G>A Ala136Ala
M0023172 JINHOBKD_00016 16050 3 Skin 0.38 protein_coding missense_variant MODERATE 344C>T Ala115Val
M0023173 JINHOBKD_00016 16151 3 Skin 0.38 protein_coding synonymous_variant LOW 243G>A Thr81Thr
M0023174 JINHOBKD_00016 16301 3 Skin 0.38 protein_coding synonymous_variant LOW 93G>A Ser31Ser
M0023175 JINHOBKD_00016 16330 3 Skin 0.38 protein_coding missense_variant MODERATE 64T>G Leu22Val
M0023176 JINHOBKD_00016 16340 3 Skin 0.38 protein_coding synonymous_variant LOW 54T>G Pro18Pro
M0023177 JINHOBKD_00017 16473 3 Skin 0.38 protein_coding synonymous_variant LOW 2319C>G Leu773Leu
M0023178 JINHOBKD_00017 16475 3 Skin 0.38 protein_coding missense_variant MODERATE 2317C>G Leu773Val
M0023179 JINHOBKD_00017 16476 3 Skin 0.38 protein_coding synonymous_variant LOW 2316T>C Leu772Leu
M0023180 JINHOBKD_00019 19747 3 Skin 0.38 protein_coding missense_variant MODERATE 77T>G Leu26Arg
M0023181 JINHOBKD_00019 19814 3 Skin 0.38 protein_coding missense_variant MODERATE 144G>A Met48Ile
M0023182 JINHOBKD_00019 20027 3 Skin 0.38 protein_coding synonymous_variant LOW 357C>T Thr119Thr
M0023183 JINHOBKD_00019 20076 3 Skin 0.38 protein_coding missense_variant MODERATE 406T>C Ser136Pro
M0023184 JINHOBKD_00019 20115 3 Skin 0.38 protein_coding missense_variant MODERATE 445G>C Asp149His
M0023185 JINHOBKD_00019 20909 3 Skin 0.38 protein_coding synonymous_variant LOW 1239T>C Leu413Leu
M0023186 JINHOBKD_00016 21002 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4609C>T None
M0023187 JINHOBKD_00020 21531 3 Skin 0.38 protein_coding missense_variant MODERATE 200G>A Gly67Asp
M0023188 JINHOBKD_00020 21582 3 Skin 0.38 protein_coding missense_variant MODERATE 149T>C Ile50Thr
M0023189 JINHOBKD_00020 21585 3 Skin 0.38 protein_coding missense_variant MODERATE 146C>T Thr49Ile
M0023190 JINHOBKD_00020 21632 3 Skin 0.38 protein_coding synonymous_variant LOW 99T>C Arg33Arg
M0023191 JINHOBKD_00020 21650 3 Skin 0.38 protein_coding synonymous_variant LOW 81T>C Leu27Leu
M0023192 JINHOBKD_00021 22152 3 Skin 0.38 protein_coding missense_variant MODERATE 122A>C Lys41Thr
M0023193 JINHOBKD_00021 22190 3 Skin 0.38 protein_coding synonymous_variant LOW 84G>A Pro28Pro
M0023194 JINHOBKD_00021 22208 3 Skin 0.38 protein_coding synonymous_variant LOW 66A>C Ser22Ser
M0023195 JINHOBKD_00021 22236 3 Skin 0.38 protein_coding missense_variant MODERATE 38T>C Met13Thr
M0023196 JINHOBKD_00021 22267 3 Skin 0.38 protein_coding missense_variant MODERATE 7G>A Ala3Thr
M0023197 JINHOBKD_00017 22285 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -3494G>C None
M0023198 JINHOBKD_00017 22413 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -3622C>G None
M0023199 JINHOBKD_00022 22847 3 Skin 0.38 protein_coding missense_variant MODERATE 512T>C Ile171Thr
M0023200 JINHOBKD_00022 22924 3 Skin 0.38 protein_coding synonymous_variant LOW 435G>A Ala145Ala
M0023201 JINHOBKD_00022 23005 3 Skin 0.38 protein_coding synonymous_variant LOW 354G>A Glu118Glu
M0023202 JINHOBKD_00022 23226 3 Skin 0.38 protein_coding missense_variant MODERATE 133C>A His45Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
JINHOBKD_00004 QWW76996.1|CBM48|GH13_11 99.4 0 1 691 1 1
JINHOBKD_00019 CDI11123.1|GH144 98.1 2.02000000009502e-314 1 417 1 0.9698





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term