Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2037
  Reference Plasmid   1111525849737158_bin.31__k141_264796
  Reference Plasmid Size   18998
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023203 OOLIHHLK_00001 179 3 Skin 0.30 protein_coding synonymous_variant LOW 534A>G Ala178Ala
M0023204 OOLIHHLK_00001 368 3 Skin 0.30 protein_coding synonymous_variant LOW 345T>C Ala115Ala
M0023205 OOLIHHLK_00001 398 3 Skin 0.30 protein_coding synonymous_variant LOW 315T>C Gly105Gly
M0023206 OOLIHHLK_00001 614 3 Skin 0.30 protein_coding synonymous_variant LOW 99A>G Leu33Leu
M0023207 OOLIHHLK_00002 981 3 Skin 0.30 protein_coding synonymous_variant LOW 621C>G Gly207Gly
M0023208 OOLIHHLK_00003 2095 3 Skin 0.30 protein_coding synonymous_variant LOW 213A>G Ala71Ala
M0023209 OOLIHHLK_00004 2952 3 Skin 0.30 protein_coding synonymous_variant LOW 126C>T His42His
M0023210 OOLIHHLK_00004 2961 3 Skin 0.30 protein_coding synonymous_variant LOW 117G>C Ala39Ala
M0023211 OOLIHHLK_00005 3089 3 Skin 0.30 protein_coding synonymous_variant LOW 1188C>G Pro396Pro
M0023212 OOLIHHLK_00005 3548 3 Skin 0.30 protein_coding synonymous_variant LOW 729A>C Thr243Thr
M0023213 OOLIHHLK_00005 3899 3 Skin 0.30 protein_coding synonymous_variant LOW 378T>G Ala126Ala
M0023214 OOLIHHLK_00005 4235 3 Skin 0.30 protein_coding synonymous_variant LOW 42C>T Ser14Ser
M0023215 OOLIHHLK_00006 4862 3 Skin 0.30 protein_coding synonymous_variant LOW 252T>C Asp84Asp
M0023216 OOLIHHLK_00006 4865 3 Skin 0.30 protein_coding synonymous_variant LOW 255T>C Ala85Ala
M0023217 OOLIHHLK_00006 5018 3 Skin 0.30 protein_coding synonymous_variant LOW 408A>G Ser136Ser
M0023218 OOLIHHLK_00007 5439 3 Skin 0.30 protein_coding synonymous_variant LOW 336T>G Ser112Ser
M0023219 OOLIHHLK_00007 5454 3 Skin 0.30 protein_coding synonymous_variant LOW 351T>C Val117Val
M0023220 OOLIHHLK_00007 5556 3 Skin 0.30 protein_coding synonymous_variant LOW 453A>T Leu151Leu
M0023221 OOLIHHLK_00007 5655 3 Skin 0.30 protein_coding synonymous_variant LOW 552C>T Gly184Gly
M0023222 OOLIHHLK_00008 6273 3 Skin 0.30 protein_coding synonymous_variant LOW 378T>C Gly126Gly
M0023223 OOLIHHLK_00015 12978 3 Skin 0.30 protein_coding missense_variant MODERATE 799C>G His267Asp
M0023224 OOLIHHLK_00015 13036 3 Skin 0.30 protein_coding synonymous_variant LOW 741T>C Asn247Asn
M0023225 OOLIHHLK_00017 15523 3 Skin 0.30 protein_coding missense_variant MODERATE 927G>C Glu309Asp
M0023226 OOLIHHLK_00018 17112 3 Skin 0.30 protein_coding missense_variant MODERATE 488C>T Ser163Phe
M0023227 OOLIHHLK_00018 17129 3 Skin 0.30 protein_coding missense_variant MODERATE 505A>G Met169Val
M0023228 OOLIHHLK_00018 17133 3 Skin 0.30 protein_coding missense_variant MODERATE 509C>T Thr170Ile
M0023229 OOLIHHLK_00015 17703 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -3927A>G None
M0023230 OOLIHHLK_00019 18245 3 Skin 0.30 protein_coding synonymous_variant LOW 444A>G Ser148Ser
M0023231 OOLIHHLK_00010 7572 3 Skin 0.30 protein_coding synonymous_variant LOW 1191G>A Gln397Gln
M0023232 OOLIHHLK_00010 7578 3 Skin 0.30 protein_coding synonymous_variant LOW 1185T>G Ala395Ala
M0023233 OOLIHHLK_00011 9130 3 Skin 0.30 protein_coding synonymous_variant LOW 1407T>C Thr469Thr
M0023234 OOLIHHLK_00011 10047 3 Skin 0.30 protein_coding missense_variant MODERATE 490G>A Val164Ile
M0023235 OOLIHHLK_00012 10912 3 Skin 0.30 protein_coding synonymous_variant LOW 99G>A Thr33Thr
M0023236 OOLIHHLK_00012 10987 3 Skin 0.30 protein_coding synonymous_variant LOW 24T>C Pro8Pro
M0023237 OOLIHHLK_00014 12146 3 Skin 0.30 protein_coding synonymous_variant LOW 543A>G Gln181Gln
M0023238 OOLIHHLK_00014 12242 3 Skin 0.30 protein_coding synonymous_variant LOW 447G>C Pro149Pro
M0023239 OOLIHHLK_00014 12406 3 Skin 0.30 protein_coding missense_variant MODERATE 283G>C Gly95Arg
M0023240 OOLIHHLK_00015 12904 3 Skin 0.30 protein_coding synonymous_variant LOW 873G>A Thr291Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
OOLIHHLK_00005 PHI:9127 bab2_0282 76 4.3e-177 1 399 1.0000 0.9975 rodents brucellosis ABC transporter permease reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
OOLIHHLK_00011 3.A.1.1.35 77.6 4.5e-268 7 573 0.9895 0.9947 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily