Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2039
  Reference Plasmid   1111525849737158_bin.5__k141_204243
  Reference Plasmid Size   36535
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023244 IIKFANNN_00020 24913 10 Skin 0.36 protein_coding missense_variant MODERATE 120C>G His40Gln
M0023245 IIKFANNN_00020 24915 10 Skin 0.36 protein_coding missense_variant MODERATE 118C>G His40Asp
M0023246 IIKFANNN_00020 24916 10 Skin 0.36 protein_coding synonymous_variant LOW 117G>C Pro39Pro
M0023247 IIKFANNN_00020 24930 10 Skin 0.36 protein_coding missense_variant MODERATE 103T>C Ser35Pro
M0023248 IIKFANNN_00020 24937 8 Skin 0.29 protein_coding synonymous_variant LOW 96C>T Gly32Gly
M0023249 IIKFANNN_00020 24963 8 Skin 0.29 protein_coding missense_variant MODERATE 70G>T Ala24Ser
M0023250 IIKFANNN_00020 24967 9 Skin 0.32 protein_coding synonymous_variant LOW 66G>C Arg22Arg
M0023251 IIKFANNN_00024 28708 9 Skin 0.32 protein_coding missense_variant MODERATE 757G>A Asp253Asn
M0023252 IIKFANNN_00018 23565 3 Skin 0.11 protein_coding synonymous_variant LOW 36T>C His12His
M0023253 IIKFANNN_00020 24202 3 Skin 0.11 protein_coding synonymous_variant LOW 831G>A Pro277Pro
M0023254 IIKFANNN_00020 24406 3 Skin 0.11 protein_coding synonymous_variant LOW 627T>C Asp209Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term