Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2045
  Reference Plasmid   1111525849737286_bin.3__k141_15600
  Reference Plasmid Size   6577
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023416 MDFOPLPN_00005 3340 3 Skin 0.50 protein_coding synonymous_variant LOW 321C>T Pro107Pro
M0023417 MDFOPLPN_00003 3757 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1797C>T None
M0023418 MDFOPLPN_00006 3907 4 Skin 0.67 protein_coding synonymous_variant LOW 148C>T Leu50Leu
M0023419 MDFOPLPN_00006 3934 3 Skin 0.50 protein_coding missense_variant MODERATE 175C>A Leu59Met
M0023420 MDFOPLPN_00006 3834 3 Skin 0.50 protein_coding synonymous_variant LOW 75C>T Ala25Ala
M0023421 MDFOPLPN_00007 4335 4 Skin 0.67 protein_coding missense_variant MODERATE 262C>G Leu88Val
M0023422 MDFOPLPN_00003 4400 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -2440C>G None
M0023423 MDFOPLPN_00008 4718 4 Skin 0.67 protein_coding missense_variant MODERATE 247C>T Pro83Ser
M0023424 MDFOPLPN_00008 4741 4 Skin 0.67 protein_coding synonymous_variant LOW 270T>G Ala90Ala
M0023425 MDFOPLPN_00008 4776 3 Skin 0.50 protein_coding missense_variant MODERATE 305G>A Ser102Asn
M0023426 MDFOPLPN_00008 4833 3 Skin 0.50 protein_coding missense_variant MODERATE 362C>G Thr121Ser
M0023427 MDFOPLPN_00008 4870 4 Skin 0.67 protein_coding synonymous_variant LOW 399G>A Glu133Glu
M0023428 MDFOPLPN_00008 5368 3 Skin 0.50 protein_coding synonymous_variant LOW 897A>G Ala299Ala
M0023429 MDFOPLPN_00009 5659 3 Skin 0.50 protein_coding synonymous_variant LOW 141G>T Arg47Arg
M0023430 MDFOPLPN_00009 5662 3 Skin 0.50 protein_coding synonymous_variant LOW 144G>C Arg48Arg
M0023431 MDFOPLPN_00009 5665 3 Skin 0.50 protein_coding synonymous_variant LOW 147G>C Val49Val
M0023432 MDFOPLPN_00009 5677 3 Skin 0.50 protein_coding synonymous_variant LOW 159T>G Ala53Ala
M0023433 MDFOPLPN_00009 5694 3 Skin 0.50 protein_coding missense_variant MODERATE 176G>A Arg59Gln
M0023434 MDFOPLPN_00009 5698 3 Skin 0.50 protein_coding synonymous_variant LOW 180A>G Ser60Ser
M0023435 MDFOPLPN_00009 5704 3 Skin 0.50 protein_coding synonymous_variant LOW 186T>C Phe62Phe
M0023436 MDFOPLPN_00006 3822 3 Skin 0.50 protein_coding missense_variant MODERATE 63G>C Glu21Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term