Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2047
  Reference Plasmid   1111525849737286_bin.7__k141_12854
  Reference Plasmid Size   3930
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023449 JNBLDBAJ_00001 260 3 Skin 1.00 protein_coding missense_variant MODERATE 152T>C Leu51Pro
M0023450 JNBLDBAJ_00002 494 3 Skin 1.00 protein_coding synonymous_variant LOW 39C>T Leu13Leu
M0023451 JNBLDBAJ_00002 503 3 Skin 1.00 protein_coding synonymous_variant LOW 48C>T Ala16Ala
M0023452 JNBLDBAJ_00002 506 3 Skin 1.00 protein_coding synonymous_variant LOW 51G>A Ala17Ala
M0023453 JNBLDBAJ_00002 518 3 Skin 1.00 protein_coding synonymous_variant LOW 63C>G Ala21Ala
M0023454 JNBLDBAJ_00002 575 3 Skin 1.00 protein_coding synonymous_variant LOW 120T>C Gly40Gly
M0023455 JNBLDBAJ_00002 743 3 Skin 1.00 protein_coding missense_variant MODERATE 288T>G Asp96Glu
M0023456 JNBLDBAJ_00002 764 3 Skin 1.00 protein_coding synonymous_variant LOW 309T>C Arg103Arg
M0023457 JNBLDBAJ_00002 791 3 Skin 1.00 protein_coding synonymous_variant LOW 336A>C Leu112Leu
M0023458 JNBLDBAJ_00002 896 3 Skin 1.00 protein_coding synonymous_variant LOW 441A>G Lys147Lys
M0023459 JNBLDBAJ_00002 1410 3 Skin 1.00 protein_coding missense_variant MODERATE 955A>G Thr319Ala
M0023460 JNBLDBAJ_00003 1996 3 Skin 1.00 protein_coding synonymous_variant LOW 306C>T Arg102Arg
M0023461 JNBLDBAJ_00003 2011 3 Skin 1.00 protein_coding synonymous_variant LOW 321A>G Pro107Pro
M0023462 JNBLDBAJ_00003 2026 3 Skin 1.00 protein_coding synonymous_variant LOW 336A>G Lys112Lys
M0023463 JNBLDBAJ_00003 2057 3 Skin 1.00 protein_coding missense_variant MODERATE 367C>G Leu123Val
M0023464 JNBLDBAJ_00003 2483 3 Skin 1.00 protein_coding missense_variant MODERATE 793A>G Thr265Ala
M0023465 JNBLDBAJ_00003 2626 3 Skin 1.00 protein_coding synonymous_variant LOW 936C>A Pro312Pro
M0023466 JNBLDBAJ_00003 2644 3 Skin 1.00 protein_coding synonymous_variant LOW 954C>T Ile318Ile
M0023467 JNBLDBAJ_00003 2676 3 Skin 1.00 protein_coding missense_variant MODERATE 986C>A Ala329Glu
M0023468 JNBLDBAJ_00003 2746 3 Skin 1.00 protein_coding synonymous_variant LOW 1056T>C Asp352Asp
M0023469 JNBLDBAJ_00003 2749 3 Skin 1.00 protein_coding synonymous_variant LOW 1059C>G Arg353Arg
M0023470 JNBLDBAJ_00003 2881 3 Skin 1.00 protein_coding synonymous_variant LOW 1191G>T Leu397Leu
M0023471 JNBLDBAJ_00003 2884 3 Skin 1.00 protein_coding synonymous_variant LOW 1194A>C Val398Val
M0023472 JNBLDBAJ_00003 2886 3 Skin 1.00 protein_coding missense_variant MODERATE 1196A>G Lys399Arg
M0023473 JNBLDBAJ_00003 2941 3 Skin 1.00 protein_coding synonymous_variant LOW 1251T>G Arg417Arg
M0023474 JNBLDBAJ_00003 2944 3 Skin 1.00 protein_coding synonymous_variant LOW 1254C>T Thr418Thr
M0023475 JNBLDBAJ_00003 2953 3 Skin 1.00 protein_coding synonymous_variant LOW 1263A>T Ile421Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term