Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2049
  Reference Plasmid   1111525849737286_bin.7__k141_19332
  Reference Plasmid Size   25913
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023477 AOPLLMPM_00005 5749 3 Skin 0.75 protein_coding synonymous_variant LOW 798A>G Pro266Pro
M0023478 AOPLLMPM_00005 5890 3 Skin 0.75 protein_coding synonymous_variant LOW 939T>G Val313Val
M0023479 AOPLLMPM_00005 5891 3 Skin 0.75 protein_coding synonymous_variant LOW 940T>C Leu314Leu
M0023480 AOPLLMPM_00005 5953 3 Skin 0.75 protein_coding synonymous_variant LOW 1002G>A Ala334Ala
M0023481 AOPLLMPM_00005 6205 3 Skin 0.75 protein_coding synonymous_variant LOW 1254A>G Thr418Thr
M0023482 AOPLLMPM_00005 6216 3 Skin 0.75 protein_coding missense_variant MODERATE 1265C>T Ala422Val
M0023483 AOPLLMPM_00005 6256 3 Skin 0.75 protein_coding synonymous_variant LOW 1305C>G Ala435Ala
M0023484 AOPLLMPM_00005 6337 3 Skin 0.75 protein_coding synonymous_variant LOW 1386G>A Glu462Glu
M0023485 AOPLLMPM_00005 7213 3 Skin 0.75 protein_coding synonymous_variant LOW 2262T>C Ala754Ala
M0023486 AOPLLMPM_00005 7273 3 Skin 0.75 protein_coding missense_variant MODERATE 2322G>C Glu774Asp
M0023487 AOPLLMPM_00005 7628 3 Skin 0.75 protein_coding missense_variant MODERATE 2677A>G Thr893Ala
M0023488 AOPLLMPM_00005 7630 3 Skin 0.75 protein_coding synonymous_variant LOW 2679C>G Thr893Thr
M0023489 AOPLLMPM_00005 7670 3 Skin 0.75 protein_coding missense_variant MODERATE 2719A>G Thr907Ala
M0023490 AOPLLMPM_00005 7699 3 Skin 0.75 protein_coding synonymous_variant LOW 2748A>G Arg916Arg
M0023491 AOPLLMPM_00005 7738 3 Skin 0.75 protein_coding synonymous_variant LOW 2787T>C Asp929Asp
M0023492 AOPLLMPM_00005 7757 3 Skin 0.75 protein_coding missense_variant MODERATE 2806C>T Pro936Ser
M0023493 AOPLLMPM_00005 7765 3 Skin 0.75 protein_coding synonymous_variant LOW 2814T>G Ala938Ala
M0023494 AOPLLMPM_00006 7991 3 Skin 0.75 protein_coding missense_variant MODERATE 211A>G Ser71Gly
M0023495 AOPLLMPM_00006 8032 3 Skin 0.75 protein_coding synonymous_variant LOW 252G>C Thr84Thr
M0023496 AOPLLMPM_00006 8065 3 Skin 0.75 protein_coding synonymous_variant LOW 285G>C Gly95Gly
M0023497 AOPLLMPM_00006 8341 3 Skin 0.75 protein_coding synonymous_variant LOW 561A>G Ala187Ala
M0023498 AOPLLMPM_00006 8359 3 Skin 0.75 protein_coding synonymous_variant LOW 579A>G Ala193Ala
M0023499 AOPLLMPM_00006 8458 3 Skin 0.75 protein_coding synonymous_variant LOW 678C>T Asp226Asp
M0023500 AOPLLMPM_00006 8461 3 Skin 0.75 protein_coding synonymous_variant LOW 681G>C Ala227Ala
M0023501 AOPLLMPM_00006 8464 3 Skin 0.75 protein_coding missense_variant MODERATE 684T>G Asp228Glu
M0023502 AOPLLMPM_00006 8467 3 Skin 0.75 protein_coding synonymous_variant LOW 687G>T Ala229Ala
M0023503 AOPLLMPM_00006 8470 3 Skin 0.75 protein_coding synonymous_variant LOW 690A>G Ala230Ala
M0023504 AOPLLMPM_00006 8527 3 Skin 0.75 protein_coding synonymous_variant LOW 747C>G Ala249Ala
M0023505 AOPLLMPM_00006 8557 3 Skin 0.75 protein_coding synonymous_variant LOW 777A>C Val259Val
M0023506 AOPLLMPM_00006 8572 3 Skin 0.75 protein_coding synonymous_variant LOW 792T>C Ala264Ala
M0023507 AOPLLMPM_00014 19182 3 Skin 0.75 protein_coding missense_variant MODERATE 830G>C Gly277Ala
M0023508 AOPLLMPM_00014 19256 3 Skin 0.75 protein_coding synonymous_variant LOW 756A>G Lys252Lys
M0023509 AOPLLMPM_00014 19351 3 Skin 0.75 protein_coding synonymous_variant LOW 661T>C Leu221Leu
M0023510 AOPLLMPM_00014 19503 3 Skin 0.75 protein_coding missense_variant MODERATE 509T>C Ile170Thr
M0023511 AOPLLMPM_00014 19585 3 Skin 0.75 protein_coding missense_variant MODERATE 427A>G Ser143Gly
M0023512 AOPLLMPM_00014 19640 3 Skin 0.75 protein_coding synonymous_variant LOW 372T>C Arg124Arg
M0023513 AOPLLMPM_00014 19667 3 Skin 0.75 protein_coding synonymous_variant LOW 345T>G Thr115Thr
M0023514 AOPLLMPM_00014 19669 3 Skin 0.75 protein_coding missense_variant MODERATE 343A>G Thr115Ala
M0023515 AOPLLMPM_00014 19823 3 Skin 0.75 protein_coding synonymous_variant LOW 189G>C Ala63Ala
M0023516 AOPLLMPM_00014 19828 3 Skin 0.75 protein_coding missense_variant MODERATE 184G>A Glu62Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term