Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2061
  Reference Plasmid   1111525849737450_bin.12__k141_100503
  Reference Plasmid Size   1973
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023791 MEPKGKAD_00001 194 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *643T>G None
M0023792 MEPKGKAD_00001 494 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *343C>G None
M0023793 MEPKGKAD_00001 1020 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -37G>A None
M0023794 MEPKGKAD_00002 1121 3 Skin 0.60 protein_coding synonymous_variant LOW 411T>C Gly137Gly
M0023795 MEPKGKAD_00002 1128 3 Skin 0.60 protein_coding missense_variant MODERATE 404T>C Ile135Thr
M0023796 MEPKGKAD_00002 1136 3 Skin 0.60 protein_coding missense_variant MODERATE 396C>G Asp132Glu
M0023797 MEPKGKAD_00002 1145 3 Skin 0.60 protein_coding synonymous_variant LOW 387G>T Ala129Ala
M0023798 MEPKGKAD_00002 1149 3 Skin 0.60 protein_coding missense_variant MODERATE 383G>A Gly128Asp
M0023799 MEPKGKAD_00002 1151 3 Skin 0.60 protein_coding synonymous_variant LOW 381C>T Phe127Phe
M0023800 MEPKGKAD_00002 1169 3 Skin 0.60 protein_coding missense_variant MODERATE 363A>C Glu121Asp
M0023801 MEPKGKAD_00002 1205 4 Skin 0.80 protein_coding synonymous_variant LOW 327A>G Ser109Ser
M0023802 MEPKGKAD_00003 1675 5 Skin 1.00 protein_coding missense_variant MODERATE 281A>G Lys94Arg
M0023803 MEPKGKAD_00003 1676 5 Skin 1.00 protein_coding missense_variant MODERATE 280A>G Lys94Glu
M0023804 MEPKGKAD_00003 1703 4 Skin 0.80 protein_coding missense_variant MODERATE 253T>C Ser85Pro
M0023805 MEPKGKAD_00001 1590 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -607G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term