Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2062
  Reference Plasmid   1111525849737450_bin.12__k141_108696
  Reference Plasmid Size   6891
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023806 MFKMCNBH_00001 1960 3 Skin 0.43 protein_coding downstream_gene_variant MODIFIER *1045G>A None
M0023807 MFKMCNBH_00001 2104 3 Skin 0.43 protein_coding downstream_gene_variant MODIFIER *1189T>G None
M0023808 MFKMCNBH_00001 2175 3 Skin 0.43 protein_coding downstream_gene_variant MODIFIER *1260C>G None
M0023809 MFKMCNBH_00003 2427 6 Skin 0.86 protein_coding synonymous_variant LOW 2157G>T Gly719Gly
M0023810 MFKMCNBH_00003 2925 4 Skin 0.57 protein_coding synonymous_variant LOW 1659A>G Gln553Gln
M0023811 MFKMCNBH_00003 3138 5 Skin 0.71 protein_coding synonymous_variant LOW 1446G>C Gly482Gly
M0023812 MFKMCNBH_00003 3498 5 Skin 0.71 protein_coding synonymous_variant LOW 1086T>G Ala362Ala
M0023813 MFKMCNBH_00003 3705 5 Skin 0.71 protein_coding synonymous_variant LOW 879A>G Ser293Ser
M0023814 MFKMCNBH_00003 4650 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -67T>C None
M0023815 MFKMCNBH_00004 4779 5 Skin 0.71 protein_coding synonymous_variant LOW 303A>G Thr101Thr
M0023816 MFKMCNBH_00004 4797 6 Skin 0.86 protein_coding synonymous_variant LOW 285A>G Lys95Lys
M0023817 MFKMCNBH_00004 4854 6 Skin 0.86 protein_coding synonymous_variant LOW 228C>T His76His
M0023818 MFKMCNBH_00003 5147 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -564G>C None
M0023819 MFKMCNBH_00003 5209 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -626C>A None
M0023820 MFKMCNBH_00005 5615 3 Skin 0.43 protein_coding synonymous_variant LOW 141T>C Pro47Pro
M0023821 MFKMCNBH_00006 6187 4 Skin 0.57 protein_coding synonymous_variant LOW 426A>G Glu142Glu
M0023822 MFKMCNBH_00006 6217 3 Skin 0.43 protein_coding synonymous_variant LOW 396A>G Ala132Ala
M0023823 MFKMCNBH_00003 6833 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -2250G>A None
M0023824 MFKMCNBH_00001 159 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -190T>C None
M0023825 MFKMCNBH_00001 762 3 Skin 0.43 protein_coding synonymous_variant LOW 414T>C Ala138Ala
M0023826 MFKMCNBH_00002 1018 3 Skin 0.43 protein_coding missense_variant MODERATE 107A>C Glu36Ala
M0023827 MFKMCNBH_00002 1517 3 Skin 0.43 protein_coding synonymous_variant LOW 606T>C Thr202Thr
M0023828 MFKMCNBH_00002 1817 3 Skin 0.43 protein_coding synonymous_variant LOW 906T>C Ala302Ala
M0023829 MFKMCNBH_00003 3555 3 Skin 0.43 protein_coding synonymous_variant LOW 1029G>A Ala343Ala
M0023830 MFKMCNBH_00003 5192 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -609C>A None
M0023831 MFKMCNBH_00006 5758 4 Skin 0.57 protein_coding synonymous_variant LOW 855C>T Ser285Ser
M0023832 MFKMCNBH_00003 6798 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2215G>A None
M0023833 MFKMCNBH_00003 5101 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -518G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term