Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2064
  Reference Plasmid   1111525849737450_bin.12__k141_41625
  Reference Plasmid Size   3018
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023835 EFHFLEGC_00002 1608 3 Skin 0.60 protein_coding synonymous_variant LOW 168C>A Gly56Gly
M0023836 EFHFLEGC_00002 1616 3 Skin 0.60 protein_coding missense_variant MODERATE 160A>T Thr54Ser
M0023837 EFHFLEGC_00002 1626 3 Skin 0.60 protein_coding synonymous_variant LOW 150G>C Val50Val
M0023838 EFHFLEGC_00002 1632 3 Skin 0.60 protein_coding synonymous_variant LOW 144T>C Cys48Cys
M0023839 EFHFLEGC_00002 1644 3 Skin 0.60 protein_coding synonymous_variant LOW 132C>T Leu44Leu
M0023840 EFHFLEGC_00002 1650 3 Skin 0.60 protein_coding synonymous_variant LOW 126G>C Ser42Ser
M0023841 EFHFLEGC_00002 1656 3 Skin 0.60 protein_coding synonymous_variant LOW 120C>T Asp40Asp
M0023842 EFHFLEGC_00002 1659 3 Skin 0.60 protein_coding missense_variant MODERATE 117T>G Asp39Glu
M0023843 EFHFLEGC_00002 1660 3 Skin 0.60 protein_coding missense_variant MODERATE 116A>G Asp39Gly
M0023844 EFHFLEGC_00002 1686 3 Skin 0.60 protein_coding synonymous_variant LOW 90C>T Asn30Asn
M0023845 EFHFLEGC_00002 1689 3 Skin 0.60 protein_coding synonymous_variant LOW 87C>G Ala29Ala
M0023846 EFHFLEGC_00002 1692 3 Skin 0.60 protein_coding synonymous_variant LOW 84G>C Gly28Gly
M0023847 EFHFLEGC_00002 1713 3 Skin 0.60 protein_coding synonymous_variant LOW 63C>T Leu21Leu
M0023848 EFHFLEGC_00002 1731 3 Skin 0.60 protein_coding synonymous_variant LOW 45C>G Val15Val
M0023849 EFHFLEGC_00002 1743 3 Skin 0.60 protein_coding synonymous_variant LOW 33T>C His11His
M0023850 EFHFLEGC_00003 1792 3 Skin 0.60 protein_coding synonymous_variant LOW 828G>A Lys276Lys
M0023851 EFHFLEGC_00003 1878 3 Skin 0.60 protein_coding missense_variant MODERATE 742C>A His248Asn
M0023852 EFHFLEGC_00001 45 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *397C>T None
M0023853 EFHFLEGC_00001 48 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *394C>T None
M0023854 EFHFLEGC_00001 75 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *367G>C None
M0023855 EFHFLEGC_00001 78 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *364T>C None
M0023856 EFHFLEGC_00001 81 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *361G>A None
M0023857 EFHFLEGC_00001 87 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *355C>T None
M0023858 EFHFLEGC_00001 93 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *349C>T None
M0023859 EFHFLEGC_00001 102 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *340T>C None
M0023860 EFHFLEGC_00001 195 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *247T>C None
M0023861 EFHFLEGC_00001 330 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *112G>A None
M0023862 EFHFLEGC_00001 625 4 Skin 0.80 protein_coding synonymous_variant LOW 537C>T Leu179Leu
M0023863 EFHFLEGC_00001 661 4 Skin 0.80 protein_coding synonymous_variant LOW 501G>A Ser167Ser
M0023864 EFHFLEGC_00001 766 3 Skin 0.60 protein_coding synonymous_variant LOW 396A>G Leu132Leu
M0023865 EFHFLEGC_00001 777 3 Skin 0.60 protein_coding missense_variant MODERATE 385G>C Glu129Gln
M0023866 EFHFLEGC_00001 793 3 Skin 0.60 protein_coding synonymous_variant LOW 369T>C Asn123Asn
M0023867 EFHFLEGC_00001 823 3 Skin 0.60 protein_coding synonymous_variant LOW 339C>T Ala113Ala
M0023868 EFHFLEGC_00001 826 3 Skin 0.60 protein_coding synonymous_variant LOW 336C>G Val112Val
M0023869 EFHFLEGC_00001 829 3 Skin 0.60 protein_coding synonymous_variant LOW 333C>G Leu111Leu
M0023870 EFHFLEGC_00001 831 3 Skin 0.60 protein_coding missense_variant MODERATE 331C>T Leu111Phe
M0023871 EFHFLEGC_00001 835 3 Skin 0.60 protein_coding synonymous_variant LOW 327C>T Leu109Leu
M0023872 EFHFLEGC_00001 838 3 Skin 0.60 protein_coding synonymous_variant LOW 324C>A Ala108Ala
M0023873 EFHFLEGC_00001 844 3 Skin 0.60 protein_coding synonymous_variant LOW 318G>C Val106Val
M0023874 EFHFLEGC_00001 847 3 Skin 0.60 protein_coding synonymous_variant LOW 315C>T Arg105Arg
M0023875 EFHFLEGC_00001 850 3 Skin 0.60 protein_coding synonymous_variant LOW 312T>C Pro104Pro
M0023876 EFHFLEGC_00001 856 3 Skin 0.60 protein_coding synonymous_variant LOW 306A>G Pro102Pro
M0023877 EFHFLEGC_00001 874 3 Skin 0.60 protein_coding synonymous_variant LOW 288G>C Val96Val
M0023878 EFHFLEGC_00001 901 3 Skin 0.60 protein_coding synonymous_variant LOW 261C>T Arg87Arg
M0023879 EFHFLEGC_00001 902 3 Skin 0.60 protein_coding missense_variant MODERATE 260G>A Arg87His
M0023880 EFHFLEGC_00001 1156 3 Skin 0.60 protein_coding synonymous_variant LOW 6A>C Thr2Thr
M0023881 EFHFLEGC_00002 1217 3 Skin 0.60 protein_coding missense_variant MODERATE 559G>C Ala187Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term