Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C13
  Reference Plasmid   1111525849737484_bin.15__k141_544092
  Reference Plasmid Size   2836
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023887 BMEIIFCJ_00001 166 5 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -36G>C None
M0023888 BMEIIFCJ_00001 193 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -9T>C None
M0023889 BMEIIFCJ_00001 203 3 Skin 0.60 protein_coding start_lost HIGH 2T>C Met1?
M0023890 BMEIIFCJ_00001 216 3 Skin 0.60 protein_coding synonymous_variant LOW 15C>T Gly5Gly
M0023891 BMEIIFCJ_00001 218 3 Skin 0.60 protein_coding missense_variant MODERATE 17C>T Pro6Leu
M0023892 BMEIIFCJ_00001 221 3 Skin 0.60 protein_coding missense_variant MODERATE 20G>T Arg7Leu
M0023893 BMEIIFCJ_00001 223 3 Skin 0.60 protein_coding missense_variant MODERATE 22G>A Ala8Thr
M0023894 BMEIIFCJ_00001 274 4 Skin 0.80 protein_coding missense_variant MODERATE 73A>G Thr25Ala
M0023895 BMEIIFCJ_00001 448 3 Skin 0.60 protein_coding missense_variant MODERATE 247A>G Ile83Val
M0023896 BMEIIFCJ_00001 478 4 Skin 0.80 protein_coding missense_variant MODERATE 277A>G Met93Val
M0023897 BMEIIFCJ_00001 724 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *181A>G None
M0023898 BMEIIFCJ_00003 1252 3 Skin 0.60 protein_coding missense_variant MODERATE 505A>G Asn169Asp
M0023899 BMEIIFCJ_00003 1303 3 Skin 0.60 protein_coding missense_variant MODERATE 454A>G Arg152Gly
M0023900 BMEIIFCJ_00003 1324 3 Skin 0.60 protein_coding missense_variant MODERATE 433A>G Thr145Ala
M0023901 BMEIIFCJ_00003 1519 3 Skin 0.60 protein_coding missense_variant MODERATE 238A>G Asn80Asp
M0023902 BMEIIFCJ_00003 1522 3 Skin 0.60 protein_coding missense_variant MODERATE 235A>G Thr79Ala
M0023903 BMEIIFCJ_00003 1537 3 Skin 0.60 protein_coding missense_variant MODERATE 220A>G Lys74Glu
M0023904 BMEIIFCJ_00003 1540 3 Skin 0.60 protein_coding missense_variant MODERATE 217A>G Ile73Val
M0118145 BMEIIFCJ_00002 1141 3 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -15A>G None
M0118146 BMEIIFCJ_00002 1148 3 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -22T>C None
M0118147 BMEIIFCJ_00003 1252 3 Oral 1.00 protein_coding missense_variant MODERATE 505A>G Asn169Asp
M0118148 BMEIIFCJ_00003 1303 3 Oral 1.00 protein_coding missense_variant MODERATE 454A>G Arg152Gly
M0118149 BMEIIFCJ_00003 1324 3 Oral 1.00 protein_coding missense_variant MODERATE 433A>G Thr145Ala
M0118150 BMEIIFCJ_00003 1519 3 Oral 1.00 protein_coding missense_variant MODERATE 238A>G Asn80Asp
M0118151 BMEIIFCJ_00003 1540 3 Oral 1.00 protein_coding missense_variant MODERATE 217A>G Ile73Val
M0118152 BMEIIFCJ_00003 1651 3 Oral 1.00 protein_coding missense_variant MODERATE 106T>C Ser36Pro
M0118153 BMEIIFCJ_00004 1897 3 Oral 1.00 protein_coding missense_variant MODERATE 268A>G Ile90Val
M0118154 BMEIIFCJ_00004 1990 3 Oral 1.00 protein_coding synonymous_variant LOW 175T>C Leu59Leu
M0118155 BMEIIFCJ_00004 2035 3 Oral 1.00 protein_coding missense_variant MODERATE 130G>A Val44Ile
M0118156 BMEIIFCJ_00005 2185 3 Oral 1.00 protein_coding stop_lost&splice_region_variant HIGH 172T>C Ter58Glnext*?
M0118157 BMEIIFCJ_00005 2354 3 Oral 1.00 protein_coding start_lost HIGH 3G>C Leu1?
M0118158 BMEIIFCJ_00006 2467 3 Oral 1.00 protein_coding missense_variant MODERATE 295A>G Ser99Gly
M0118159 BMEIIFCJ_00006 2488 3 Oral 1.00 protein_coding missense_variant MODERATE 274C>T Leu92Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term