Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2070
  Reference Plasmid   1111525849737518_bin.14__k141_78317
  Reference Plasmid Size   13920
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0023985 BEPCDDAH_00008 6844 5 Skin 0.71 protein_coding synonymous_variant LOW 1557T>C Pro519Pro
M0023986 BEPCDDAH_00008 6877 4 Skin 0.57 protein_coding synonymous_variant LOW 1524C>G Thr508Thr
M0023987 BEPCDDAH_00008 6886 4 Skin 0.57 protein_coding synonymous_variant LOW 1515T>C His505His
M0023988 BEPCDDAH_00008 6897 4 Skin 0.57 protein_coding missense_variant MODERATE 1504A>G Thr502Ala
M0023989 BEPCDDAH_00008 6917 5 Skin 0.71 protein_coding missense_variant MODERATE 1484T>C Val495Ala
M0023990 BEPCDDAH_00008 7365 5 Skin 0.71 protein_coding missense_variant MODERATE 1036T>C Ser346Pro
M0023991 BEPCDDAH_00008 7378 5 Skin 0.71 protein_coding synonymous_variant LOW 1023C>G Val341Val
M0023992 BEPCDDAH_00008 7623 4 Skin 0.57 protein_coding missense_variant MODERATE 778G>C Ala260Pro
M0023993 BEPCDDAH_00008 7810 5 Skin 0.71 protein_coding synonymous_variant LOW 591T>C Gly197Gly
M0023994 BEPCDDAH_00008 7891 3 Skin 0.43 protein_coding synonymous_variant LOW 510G>C Ala170Ala
M0023995 BEPCDDAH_00008 8032 4 Skin 0.57 protein_coding synonymous_variant LOW 369T>C Val123Val
M0023996 BEPCDDAH_00008 8077 5 Skin 0.71 protein_coding synonymous_variant LOW 324A>G Val108Val
M0023997 BEPCDDAH_00008 8364 5 Skin 0.71 protein_coding missense_variant MODERATE 37A>G Arg13Gly
M0023998 BEPCDDAH_00009 9204 3 Skin 0.43 protein_coding synonymous_variant LOW 12G>C Leu4Leu
M0023999 BEPCDDAH_00010 9356 4 Skin 0.57 protein_coding synonymous_variant LOW 795C>G Gly265Gly
M0024000 BEPCDDAH_00010 9407 3 Skin 0.43 protein_coding synonymous_variant LOW 744C>G Leu248Leu
M0024001 BEPCDDAH_00010 9812 3 Skin 0.43 protein_coding synonymous_variant LOW 339C>T Phe113Phe
M0024002 BEPCDDAH_00007 6733 3 Skin 0.43 protein_coding synonymous_variant LOW 24A>G Glu8Glu
M0024003 BEPCDDAH_00008 7489 4 Skin 0.57 protein_coding synonymous_variant LOW 912G>A Glu304Glu
M0024004 BEPCDDAH_00008 8167 3 Skin 0.43 protein_coding synonymous_variant LOW 234C>T Asp78Asp
M0024005 BEPCDDAH_00008 8182 4 Skin 0.57 protein_coding missense_variant MODERATE 219T>A Asp73Glu
M0024006 BEPCDDAH_00004 2475 3 Skin 0.43 protein_coding synonymous_variant LOW 639C>G Ala213Ala
M0024007 BEPCDDAH_00004 2508 3 Skin 0.43 protein_coding synonymous_variant LOW 606G>C Ser202Ser
M0024008 BEPCDDAH_00005 3609 3 Skin 0.43 protein_coding synonymous_variant LOW 333A>G Ala111Ala
M0024009 BEPCDDAH_00008 7033 3 Skin 0.43 protein_coding synonymous_variant LOW 1368G>T Arg456Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BEPCDDAH_00002 3.A.1.3.7 84.4 2.4e-120 16 259 0.9421 0.9278 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily