Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2081
  Reference Plasmid   1111525849739531_bin.13__k141_70919
  Reference Plasmid Size   62474
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0024316 LEKHNGMG_00001 119 5 Skin 0.07 protein_coding missense_variant MODERATE 19G>C Gly7Arg
M0024317 LEKHNGMG_00001 157 5 Skin 0.07 protein_coding synonymous_variant LOW 57T>C Val19Val
M0024318 LEKHNGMG_00001 207 5 Skin 0.07 protein_coding missense_variant MODERATE 107G>A Arg36Lys
M0024319 LEKHNGMG_00001 216 5 Skin 0.07 protein_coding missense_variant MODERATE 116G>C Gly39Ala
M0024320 LEKHNGMG_00001 499 5 Skin 0.07 protein_coding synonymous_variant LOW 399G>A Ala133Ala
M0024321 LEKHNGMG_00001 505 5 Skin 0.07 protein_coding synonymous_variant LOW 405A>G Gln135Gln
M0024322 LEKHNGMG_00001 517 5 Skin 0.07 protein_coding synonymous_variant LOW 417G>C Leu139Leu
M0024323 LEKHNGMG_00001 538 5 Skin 0.07 protein_coding synonymous_variant LOW 438T>G Leu146Leu
M0024324 LEKHNGMG_00001 541 5 Skin 0.07 protein_coding synonymous_variant LOW 441G>C Pro147Pro
M0024325 LEKHNGMG_00001 552 5 Skin 0.07 protein_coding missense_variant MODERATE 452T>C Val151Ala
M0024326 LEKHNGMG_00002 2013 7 Skin 0.10 protein_coding missense_variant MODERATE 703G>A Val235Ile
M0024327 LEKHNGMG_00014 10998 3 Skin 0.04 protein_coding synonymous_variant LOW 480G>A Arg160Arg
M0024328 LEKHNGMG_00014 11007 3 Skin 0.04 protein_coding synonymous_variant LOW 489G>C Pro163Pro
M0024329 LEKHNGMG_00014 11051 3 Skin 0.04 protein_coding missense_variant MODERATE 533T>C Val178Ala
M0024330 LEKHNGMG_00014 11052 3 Skin 0.04 protein_coding synonymous_variant LOW 534A>C Val178Val
M0024331 LEKHNGMG_00014 11077 3 Skin 0.04 protein_coding missense_variant MODERATE 559G>A Val187Ile
M0024332 LEKHNGMG_00046 44494 10 Skin 0.15 protein_coding synonymous_variant LOW 354C>T Asp118Asp
M0024333 LEKHNGMG_00047 45914 3 Skin 0.04 protein_coding synonymous_variant LOW 199T>C Leu67Leu
M0024334 LEKHNGMG_00047 45915 3 Skin 0.04 protein_coding synonymous_variant LOW 198T>A Ala66Ala
M0024335 LEKHNGMG_00047 45916 3 Skin 0.04 protein_coding missense_variant MODERATE 197C>A Ala66Asp
M0024336 LEKHNGMG_00048 46443 3 Skin 0.04 protein_coding synonymous_variant LOW 171T>C Pro57Pro
M0024337 LEKHNGMG_00048 46446 3 Skin 0.04 protein_coding synonymous_variant LOW 168T>C Ser56Ser
M0024338 LEKHNGMG_00050 48753 5 Skin 0.07 protein_coding missense_variant MODERATE 569T>C Leu190Pro
M0024339 LEKHNGMG_00034 31128 3 Skin 0.04 protein_coding synonymous_variant LOW 1731C>T Ser577Ser
M0024340 LEKHNGMG_00034 31149 3 Skin 0.04 protein_coding synonymous_variant LOW 1752C>T Gly584Gly
M0024341 LEKHNGMG_00053 53659 3 Skin 0.04 protein_coding synonymous_variant LOW 1110G>A Glu370Glu
M0024342 LEKHNGMG_00053 53668 3 Skin 0.04 protein_coding synonymous_variant LOW 1101T>C Val367Val
M0024343 LEKHNGMG_00053 53670 3 Skin 0.04 protein_coding missense_variant MODERATE 1099G>A Val367Ile
M0024344 LEKHNGMG_00053 53959 3 Skin 0.04 protein_coding synonymous_variant LOW 810T>G Leu270Leu
M0024345 LEKHNGMG_00053 53961 3 Skin 0.04 protein_coding missense_variant MODERATE 808C>T Leu270Phe
M0024346 LEKHNGMG_00017 13408 4 Skin 0.06 protein_coding synonymous_variant LOW 420A>G Gln140Gln
M0024347 LEKHNGMG_00053 53035 3 Skin 0.04 protein_coding synonymous_variant LOW 1734C>T Phe578Phe
M0024348 LEKHNGMG_00053 53038 3 Skin 0.04 protein_coding synonymous_variant LOW 1731G>C Pro577Pro
M0024349 LEKHNGMG_00053 53090 3 Skin 0.04 protein_coding missense_variant MODERATE 1679C>G Thr560Ser
M0024350 LEKHNGMG_00047 45861 4 Skin 0.06 protein_coding synonymous_variant LOW 252T>G Val84Val
M0024351 LEKHNGMG_00027 23519 12 Skin 0.18 protein_coding stop_lost&splice_region_variant HIGH 475T>G Ter159Glyext*?
M0024352 LEKHNGMG_00030 26771 3 Skin 0.04 protein_coding synonymous_variant LOW 117T>C Gly39Gly
M0024353 LEKHNGMG_00026 22362 4 Skin 0.06 protein_coding synonymous_variant LOW 1092C>T Asn364Asn
M0024354 LEKHNGMG_00026 22368 4 Skin 0.06 protein_coding synonymous_variant LOW 1086A>G Gly362Gly
M0024355 LEKHNGMG_00051 50105 3 Skin 0.04 protein_coding synonymous_variant LOW 1065C>T Arg355Arg
M0024356 LEKHNGMG_00051 50108 3 Skin 0.04 protein_coding synonymous_variant LOW 1068A>G Ala356Ala
M0024357 LEKHNGMG_00053 53344 3 Skin 0.04 protein_coding synonymous_variant LOW 1425G>A Lys475Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term