Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2086
  Reference Plasmid   1111525849740170_bin.15__k141_290973
  Reference Plasmid Size   8066
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0118169 BDDLOEPF_00001 579 3 Oral 0.75 protein_coding synonymous_variant LOW 294A>G Lys98Lys
M0118170 BDDLOEPF_00001 588 3 Oral 0.75 protein_coding synonymous_variant LOW 303T>C Ala101Ala
M0118171 BDDLOEPF_00001 619 4 Oral 1.00 protein_coding missense_variant MODERATE 334A>G Thr112Ala
M0118172 BDDLOEPF_00001 625 4 Oral 1.00 protein_coding missense_variant MODERATE 340G>A Asp114Asn
M0118173 BDDLOEPF_00001 627 4 Oral 1.00 protein_coding synonymous_variant LOW 342T>C Asp114Asp
M0118174 BDDLOEPF_00001 633 4 Oral 1.00 protein_coding synonymous_variant LOW 348A>G Lys116Lys
M0118175 BDDLOEPF_00001 634 4 Oral 1.00 protein_coding synonymous_variant LOW 349C>T Leu117Leu
M0118176 BDDLOEPF_00001 650 4 Oral 1.00 protein_coding missense_variant MODERATE 365C>A Thr122Asn
M0118177 BDDLOEPF_00001 654 4 Oral 1.00 protein_coding synonymous_variant LOW 369A>T Ala123Ala
M0118178 BDDLOEPF_00001 807 4 Oral 1.00 protein_coding synonymous_variant LOW 522G>A Gly174Gly
M0118179 BDDLOEPF_00001 846 4 Oral 1.00 protein_coding synonymous_variant LOW 561C>T Tyr187Tyr
M0118180 BDDLOEPF_00001 999 4 Oral 1.00 protein_coding synonymous_variant LOW 714A>G Glu238Glu
M0118181 BDDLOEPF_00001 1134 4 Oral 1.00 protein_coding synonymous_variant LOW 849A>C Val283Val
M0118182 BDDLOEPF_00001 1290 4 Oral 1.00 protein_coding synonymous_variant LOW 1005G>A Gln335Gln
M0118183 BDDLOEPF_00001 1413 3 Oral 0.75 protein_coding synonymous_variant LOW 1128C>T Thr376Thr
M0118184 BDDLOEPF_00001 1458 4 Oral 1.00 protein_coding synonymous_variant LOW 1173A>G Ser391Ser
M0118185 BDDLOEPF_00001 1590 4 Oral 1.00 protein_coding synonymous_variant LOW 1305G>A Arg435Arg
M0118186 BDDLOEPF_00001 1594 4 Oral 1.00 protein_coding missense_variant MODERATE 1309A>G Asn437Asp
M0118187 BDDLOEPF_00001 1617 4 Oral 1.00 protein_coding synonymous_variant LOW 1332T>C Ala444Ala
M0118188 BDDLOEPF_00001 1629 4 Oral 1.00 protein_coding missense_variant MODERATE 1344T>A Asn448Lys
M0118189 BDDLOEPF_00001 1725 4 Oral 1.00 protein_coding synonymous_variant LOW 1440T>A Ala480Ala
M0118190 BDDLOEPF_00001 1782 3 Oral 0.75 protein_coding missense_variant MODERATE 1497C>G Ile499Met
M0118191 BDDLOEPF_00001 1812 4 Oral 1.00 protein_coding synonymous_variant LOW 1527G>T Val509Val
M0118192 BDDLOEPF_00001 1860 4 Oral 1.00 protein_coding synonymous_variant LOW 1575G>C Gly525Gly
M0118193 BDDLOEPF_00003 3231 3 Oral 0.75 protein_coding missense_variant MODERATE 49C>G Leu17Val
M0118194 BDDLOEPF_00003 3270 3 Oral 0.75 protein_coding missense_variant MODERATE 88A>G Ile30Val
M0118195 BDDLOEPF_00003 3863 3 Oral 0.75 protein_coding synonymous_variant LOW 681T>G Ala227Ala
M0118196 BDDLOEPF_00003 3938 3 Oral 0.75 protein_coding synonymous_variant LOW 756T>A Ala252Ala
M0118197 BDDLOEPF_00003 3999 3 Oral 0.75 protein_coding missense_variant MODERATE 817A>G Ile273Val
M0118198 BDDLOEPF_00003 4361 3 Oral 0.75 protein_coding synonymous_variant LOW 1179T>C Ile393Ile
M0118199 BDDLOEPF_00003 4388 3 Oral 0.75 protein_coding synonymous_variant LOW 1206G>T Ala402Ala
M0118200 BDDLOEPF_00003 4562 3 Oral 0.75 protein_coding synonymous_variant LOW 1380A>G Val460Val
M0118201 BDDLOEPF_00004 4828 3 Oral 0.75 protein_coding synonymous_variant LOW 159A>G Ala53Ala
M0118202 BDDLOEPF_00001 901 3 Oral 0.75 protein_coding missense_variant MODERATE 616A>G Asn206Asp
M0118203 BDDLOEPF_00001 1404 3 Oral 0.75 protein_coding synonymous_variant LOW 1119G>A Glu373Glu
M0118204 BDDLOEPF_00001 1878 3 Oral 0.75 protein_coding synonymous_variant LOW 1593G>A Gly531Gly
M0118205 BDDLOEPF_00001 2043 3 Oral 0.75 protein_coding missense_variant MODERATE 1758G>T Lys586Asn
M0118206 BDDLOEPF_00001 2313 3 Oral 0.75 protein_coding synonymous_variant LOW 2028T>C Tyr676Tyr
M0118207 BDDLOEPF_00001 2349 3 Oral 0.75 protein_coding synonymous_variant LOW 2064A>T Val688Val
M0118208 BDDLOEPF_00002 2593 3 Oral 0.75 protein_coding synonymous_variant LOW 213A>T Ile71Ile
M0118209 BDDLOEPF_00002 2647 3 Oral 0.75 protein_coding synonymous_variant LOW 267T>C Asn89Asn
M0118210 BDDLOEPF_00002 2788 3 Oral 0.75 protein_coding synonymous_variant LOW 408A>G Leu136Leu
M0118211 BDDLOEPF_00002 2833 3 Oral 0.75 protein_coding synonymous_variant LOW 453T>C Gly151Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BDDLOEPF_00001 UWP38398.1|GH0 94.6 0 1 701 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term