Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2090
  Reference Plasmid   1111525849740170_bin.34__k141_92056
  Reference Plasmid Size   34268
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0024450 NGCNOMGA_00024 26086 3 Skin 0.50 protein_coding synonymous_variant LOW 183C>A Ala61Ala
M0024451 NGCNOMGA_00024 26128 3 Skin 0.50 protein_coding synonymous_variant LOW 225T>C Ala75Ala
M0024452 NGCNOMGA_00024 26372 3 Skin 0.50 protein_coding missense_variant MODERATE 469C>G Leu157Val
M0024453 NGCNOMGA_00024 26374 3 Skin 0.50 protein_coding synonymous_variant LOW 471A>C Leu157Leu
M0024454 NGCNOMGA_00024 26431 3 Skin 0.50 protein_coding synonymous_variant LOW 528A>G Val176Val
M0024455 NGCNOMGA_00024 26500 3 Skin 0.50 protein_coding synonymous_variant LOW 597C>T Ala199Ala
M0024456 NGCNOMGA_00024 26884 3 Skin 0.50 protein_coding synonymous_variant LOW 981C>T Cys327Cys
M0024457 NGCNOMGA_00024 26890 3 Skin 0.50 protein_coding synonymous_variant LOW 987C>T Gly329Gly
M0024458 NGCNOMGA_00024 27092 3 Skin 0.50 protein_coding missense_variant MODERATE 1189A>C Thr397Pro
M0024459 NGCNOMGA_00024 27103 3 Skin 0.50 protein_coding synonymous_variant LOW 1200G>A Lys400Lys
M0024460 NGCNOMGA_00024 27286 4 Skin 0.67 protein_coding synonymous_variant LOW 1383T>A Thr461Thr
M0024461 NGCNOMGA_00024 27460 3 Skin 0.50 protein_coding synonymous_variant LOW 1557A>G Pro519Pro
M0024462 NGCNOMGA_00025 27612 3 Skin 0.50 protein_coding synonymous_variant LOW 58C>T Leu20Leu
M0024463 NGCNOMGA_00025 27615 3 Skin 0.50 protein_coding synonymous_variant LOW 61T>C Leu21Leu
M0024464 NGCNOMGA_00026 28279 3 Skin 0.50 protein_coding synonymous_variant LOW 42A>C Ile14Ile
M0024465 NGCNOMGA_00026 28676 3 Skin 0.50 protein_coding missense_variant MODERATE 439T>G Cys147Gly
M0024466 NGCNOMGA_00026 28894 3 Skin 0.50 protein_coding synonymous_variant LOW 657G>A Ala219Ala
M0024467 NGCNOMGA_00026 28948 3 Skin 0.50 protein_coding synonymous_variant LOW 711C>T Pro237Pro
M0024468 NGCNOMGA_00026 29317 4 Skin 0.67 protein_coding synonymous_variant LOW 1080T>C Val360Val
M0024469 NGCNOMGA_00026 29428 4 Skin 0.67 protein_coding synonymous_variant LOW 1191T>C His397His
M0024470 NGCNOMGA_00026 29557 3 Skin 0.50 protein_coding synonymous_variant LOW 1320T>C Ile440Ile
M0024471 NGCNOMGA_00027 29809 3 Skin 0.50 protein_coding synonymous_variant LOW 582G>A Ser194Ser
M0024472 NGCNOMGA_00027 30313 3 Skin 0.50 protein_coding synonymous_variant LOW 78A>T Thr26Thr
M0024473 NGCNOMGA_00028 30483 4 Skin 0.67 protein_coding missense_variant MODERATE 671T>C Leu224Ser
M0024474 NGCNOMGA_00028 30518 3 Skin 0.50 protein_coding synonymous_variant LOW 636A>G Val212Val
M0024475 NGCNOMGA_00028 30522 4 Skin 0.67 protein_coding missense_variant MODERATE 632C>T Ala211Val
M0024476 NGCNOMGA_00028 30578 3 Skin 0.50 protein_coding synonymous_variant LOW 576A>T Ala192Ala
M0024477 NGCNOMGA_00028 30610 4 Skin 0.67 protein_coding missense_variant MODERATE 544T>G Ser182Ala
M0024478 NGCNOMGA_00028 30653 3 Skin 0.50 protein_coding synonymous_variant LOW 501G>A Lys167Lys
M0024479 NGCNOMGA_00028 30683 4 Skin 0.67 protein_coding synonymous_variant LOW 471G>T Gly157Gly
M0024480 NGCNOMGA_00028 30694 4 Skin 0.67 protein_coding synonymous_variant LOW 460T>C Leu154Leu
M0024481 NGCNOMGA_00028 30847 4 Skin 0.67 protein_coding synonymous_variant LOW 307C>T Leu103Leu
M0024482 NGCNOMGA_00028 31062 3 Skin 0.50 protein_coding missense_variant MODERATE 92A>G Asn31Ser
M0024483 NGCNOMGA_00028 31112 3 Skin 0.50 protein_coding synonymous_variant LOW 42G>A Leu14Leu
M0024484 NGCNOMGA_00028 31121 3 Skin 0.50 protein_coding synonymous_variant LOW 33A>C Thr11Thr
M0024485 NGCNOMGA_00029 31377 4 Skin 0.67 protein_coding synonymous_variant LOW 1080T>C Gly360Gly
M0024486 NGCNOMGA_00029 32010 3 Skin 0.50 protein_coding synonymous_variant LOW 447A>T Thr149Thr
M0024487 NGCNOMGA_00009 10714 3 Skin 0.50 protein_coding missense_variant MODERATE 302G>A Arg101His
M0024488 NGCNOMGA_00009 10793 3 Skin 0.50 protein_coding synonymous_variant LOW 381C>T Tyr127Tyr
M0024489 NGCNOMGA_00009 10854 3 Skin 0.50 protein_coding missense_variant MODERATE 442C>G Leu148Val
M0024490 NGCNOMGA_00009 11421 3 Skin 0.50 protein_coding missense_variant MODERATE 1009A>C Lys337Gln
M0024491 NGCNOMGA_00010 11963 3 Skin 0.50 protein_coding synonymous_variant LOW 279T>A Pro93Pro
M0024492 NGCNOMGA_00010 12149 3 Skin 0.50 protein_coding synonymous_variant LOW 465A>T Gly155Gly
M0024493 NGCNOMGA_00006 12380 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4092T>A None
M0024494 NGCNOMGA_00011 12810 3 Skin 0.50 protein_coding missense_variant MODERATE 385A>C Ile129Leu
M0024495 NGCNOMGA_00011 12932 3 Skin 0.50 protein_coding synonymous_variant LOW 507T>C Ile169Ile
M0024496 NGCNOMGA_00011 12985 3 Skin 0.50 protein_coding missense_variant MODERATE 560C>T Ser187Leu
M0024497 NGCNOMGA_00011 12989 3 Skin 0.50 protein_coding synonymous_variant LOW 564C>T Ala188Ala
M0024498 NGCNOMGA_00011 13110 3 Skin 0.50 protein_coding missense_variant MODERATE 685T>A Ser229Thr
M0024499 NGCNOMGA_00011 13160 3 Skin 0.50 protein_coding synonymous_variant LOW 735C>T Leu245Leu
M0024500 NGCNOMGA_00011 13166 3 Skin 0.50 protein_coding synonymous_variant LOW 741C>T Asp247Asp
M0024501 NGCNOMGA_00011 13442 3 Skin 0.50 protein_coding synonymous_variant LOW 1017C>T Gly339Gly
M0024502 NGCNOMGA_00011 13499 3 Skin 0.50 protein_coding synonymous_variant LOW 1074T>C Arg358Arg
M0024503 NGCNOMGA_00011 13553 3 Skin 0.50 protein_coding synonymous_variant LOW 1128T>C Ala376Ala
M0024504 NGCNOMGA_00011 13559 3 Skin 0.50 protein_coding synonymous_variant LOW 1134T>C Cys378Cys
M0024505 NGCNOMGA_00011 13565 3 Skin 0.50 protein_coding synonymous_variant LOW 1140A>G Pro380Pro
M0024506 NGCNOMGA_00011 13571 3 Skin 0.50 protein_coding synonymous_variant LOW 1146G>A Leu382Leu
M0024507 NGCNOMGA_00011 13704 3 Skin 0.50 protein_coding synonymous_variant LOW 1279C>A Arg427Arg
M0024508 NGCNOMGA_00012 13916 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -282T>C None
M0024509 NGCNOMGA_00012 13946 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -252T>C None
M0024510 NGCNOMGA_00012 14584 3 Skin 0.50 protein_coding synonymous_variant LOW 387A>T Ala129Ala
M0024511 NGCNOMGA_00012 14623 3 Skin 0.50 protein_coding synonymous_variant LOW 426T>C Gly142Gly
M0024512 NGCNOMGA_00012 14710 3 Skin 0.50 protein_coding synonymous_variant LOW 513T>C Ile171Ile
M0024513 NGCNOMGA_00012 14953 3 Skin 0.50 protein_coding synonymous_variant LOW 756C>T Phe252Phe
M0024514 NGCNOMGA_00026 28471 3 Skin 0.50 protein_coding synonymous_variant LOW 234A>G Leu78Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term