Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2095
  Reference Plasmid   1111525849742797_bin.26__k141_245209
  Reference Plasmid Size   23470
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0024676 DMPAHPMB_00022 23431 13 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -2344G>A None
M0024677 DMPAHPMB_00001 268 6 Skin 0.12 protein_coding synonymous_variant LOW 72T>C Asn24Asn
M0024678 DMPAHPMB_00014 11021 3 Skin 0.06 protein_coding synonymous_variant LOW 12C>T Tyr4Tyr
M0024679 DMPAHPMB_00014 11022 3 Skin 0.06 protein_coding missense_variant MODERATE 11A>C Tyr4Ser
M0024680 DMPAHPMB_00014 11028 3 Skin 0.06 protein_coding missense_variant MODERATE 5C>A Pro2His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
DMPAHPMB_00019 VFG048611 Aerobactin 71.1 0 4 745 0.996 1.0234 Nutritional/Metabolic factor ferric aerobactin receptor IutA prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
DMPAHPMB_00014 PHI:4184 ypo0988 85.7 7.8e-190 1 407 1.0000 1.0000 rodents bubonic plague putative DNA binding protein reduced virulence
DMPAHPMB_00015 PHI:11683 iucA (ypk_0786) 86.1 1.6e-297 1 578 0.9948 0.9881 rodents gut-associated disease; diarrhea; enteritis; colitis aerobactin siderophore biosynthesis protein reduced virulence
DMPAHPMB_00019 PHI:11684 iutA (ypk_0782) 81.8 0 1 745 1.0000 1.0000 rodents gut-associated disease; diarrhea; enteritis; colitis putative ferric siderophore receptor reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
DMPAHPMB_00022 QQX54510.1|CE4 96.5 1.78e-238 1 312 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
DMPAHPMB_00019 1.B.14.9.3 81.9 0 1 745 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family