Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2101
  Reference Plasmid   1111525849742797_bin.28__k141_176011
  Reference Plasmid Size   28176
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0024778 HLGPKBIN_00003 614 54 Skin 0.63 protein_coding synonymous_variant LOW 489C>T Tyr163Tyr
M0024779 HLGPKBIN_00003 986 8 Skin 0.09 protein_coding synonymous_variant LOW 117C>G Leu39Leu
M0024780 HLGPKBIN_00003 998 7 Skin 0.08 protein_coding synonymous_variant LOW 105C>T Ile35Ile
M0024781 HLGPKBIN_00005 2165 19 Skin 0.22 protein_coding missense_variant MODERATE 118T>G Ser40Ala
M0024782 HLGPKBIN_00002 1116 10 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -638C>T None
M0024783 HLGPKBIN_00008 7827 37 Skin 0.43 protein_coding synonymous_variant LOW 3000C>A Val1000Val
M0024784 HLGPKBIN_00014 12760 23 Skin 0.27 protein_coding synonymous_variant LOW 96A>G Val32Val
M0024785 HLGPKBIN_00013 14117 24 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -2123C>T None
M0024786 HLGPKBIN_00024 21991 14 Skin 0.16 protein_coding synonymous_variant LOW 42C>G Pro14Pro
M0024787 HLGPKBIN_00021 23059 13 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -3974C>T None
M0024788 HLGPKBIN_00005 225 22 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -1823T>C None
M0024789 HLGPKBIN_00004 1621 3 Skin 0.03 protein_coding synonymous_variant LOW 70C>T Leu24Leu
M0024790 HLGPKBIN_00004 1625 3 Skin 0.03 protein_coding synonymous_variant LOW 66G>A Glu22Glu
M0024791 HLGPKBIN_00004 1640 3 Skin 0.03 protein_coding synonymous_variant LOW 51A>G Gln17Gln
M0024792 HLGPKBIN_00002 455 8 Skin 0.09 protein_coding synonymous_variant LOW 24T>C Tyr8Tyr
M0024793 HLGPKBIN_00005 2761 7 Skin 0.08 protein_coding missense_variant MODERATE 714T>A Asp238Glu
M0024794 HLGPKBIN_00002 1738 9 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -1260G>C None
M0024795 HLGPKBIN_00005 2315 13 Skin 0.15 protein_coding synonymous_variant LOW 268T>C Leu90Leu
M0024796 HLGPKBIN_00005 2320 13 Skin 0.15 protein_coding synonymous_variant LOW 273T>C Gly91Gly
M0024797 HLGPKBIN_00021 23075 12 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -3990G>A None
M0024798 HLGPKBIN_00007 4406 9 Skin 0.10 protein_coding synonymous_variant LOW 150G>A Leu50Leu
M0024799 HLGPKBIN_00008 5745 5 Skin 0.06 protein_coding synonymous_variant LOW 918C>G Ala306Ala
M0024800 HLGPKBIN_00008 5763 5 Skin 0.06 protein_coding synonymous_variant LOW 936C>G Gly312Gly
M0024801 HLGPKBIN_00008 7971 6 Skin 0.07 protein_coding synonymous_variant LOW 3144C>A Gly1048Gly
M0024802 HLGPKBIN_00021 18207 3 Skin 0.03 protein_coding synonymous_variant LOW 879T>C Phe293Phe
M0024803 HLGPKBIN_00029 27626 3 Skin 0.03 protein_coding synonymous_variant LOW 292T>C Leu98Leu
M0024804 HLGPKBIN_00004 1495 6 Skin 0.07 protein_coding missense_variant MODERATE 196G>A Gly66Ser
M0024805 HLGPKBIN_00014 17486 3 Skin 0.03 protein_coding upstream_gene_variant MODIFIER -4631C>A None
M0024806 HLGPKBIN_00006 3391 10 Skin 0.12 protein_coding synonymous_variant LOW 33A>G Pro11Pro
M0024807 HLGPKBIN_00008 7434 4 Skin 0.05 protein_coding synonymous_variant LOW 2607C>T Arg869Arg
M0024808 HLGPKBIN_00011 9993 5 Skin 0.06 protein_coding synonymous_variant LOW 333G>A Pro111Pro
M0024809 HLGPKBIN_00022 19956 5 Skin 0.06 protein_coding synonymous_variant LOW 583T>C Leu195Leu
M0024810 HLGPKBIN_00005 3154 6 Skin 0.07 protein_coding synonymous_variant LOW 1107C>T Gly369Gly
M0024811 HLGPKBIN_00016 14606 3 Skin 0.03 protein_coding synonymous_variant LOW 387G>C Thr129Thr
M0024812 HLGPKBIN_00011 9891 3 Skin 0.03 protein_coding synonymous_variant LOW 231G>A Lys77Lys
M0024813 HLGPKBIN_00015 13467 4 Skin 0.05 protein_coding synonymous_variant LOW 585C>G Gly195Gly
M0024814 HLGPKBIN_00015 13479 4 Skin 0.05 protein_coding synonymous_variant LOW 573A>C Ala191Ala
M0024815 HLGPKBIN_00005 2072 4 Skin 0.05 protein_coding missense_variant MODERATE 25C>T Pro9Ser
M0024816 HLGPKBIN_00015 13138 4 Skin 0.05 protein_coding missense_variant MODERATE 914T>C Val305Ala
M0024817 HLGPKBIN_00002 4190 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3712T>G None
M0024818 HLGPKBIN_00005 2244 4 Skin 0.05 protein_coding missense_variant MODERATE 197C>G Ser66Trp
M0024819 HLGPKBIN_00009 8777 3 Skin 0.03 protein_coding synonymous_variant LOW 504C>G Gly168Gly
M0024820 HLGPKBIN_00022 19705 3 Skin 0.03 protein_coding missense_variant MODERATE 332T>C Val111Ala
M0024821 HLGPKBIN_00013 11830 3 Skin 0.03 protein_coding synonymous_variant LOW 165G>A Lys55Lys
M0024822 HLGPKBIN_00015 13788 4 Skin 0.05 protein_coding synonymous_variant LOW 264C>T Asn88Asn
M0024823 HLGPKBIN_00015 13053 3 Skin 0.03 protein_coding synonymous_variant LOW 999T>C Gly333Gly
M0024824 HLGPKBIN_00004 1451 3 Skin 0.03 protein_coding synonymous_variant LOW 240A>G Val80Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term