Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2102
  Reference Plasmid   1111525849742797_bin.36__k141_271933
  Reference Plasmid Size   21064
  Reference Plasmid GC Content   0.72
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0024825 HFHMMHDH_00003 1856 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -137G>A None
M0024826 HFHMMHDH_00003 2618 4 Skin 1.00 protein_coding missense_variant MODERATE 626C>A Thr209Asn
M0024827 HFHMMHDH_00003 2631 4 Skin 1.00 protein_coding synonymous_variant LOW 639T>C Pro213Pro
M0024828 HFHMMHDH_00004 3751 4 Skin 1.00 protein_coding synonymous_variant LOW 633T>C Ala211Ala
M0024829 HFHMMHDH_00006 4556 4 Skin 1.00 protein_coding missense_variant MODERATE 77T>C Val26Ala
M0024830 HFHMMHDH_00008 7541 4 Skin 1.00 protein_coding missense_variant MODERATE 496A>G Lys166Glu
M0024831 HFHMMHDH_00008 7562 4 Skin 1.00 protein_coding missense_variant MODERATE 517T>G Leu173Val
M0024832 HFHMMHDH_00008 7714 4 Skin 1.00 protein_coding synonymous_variant LOW 669C>G Ala223Ala
M0024833 HFHMMHDH_00009 7853 3 Skin 0.75 protein_coding missense_variant MODERATE 59T>C Leu20Pro
M0024834 HFHMMHDH_00010 8179 4 Skin 1.00 protein_coding missense_variant MODERATE 254C>T Thr85Ile
M0024835 HFHMMHDH_00011 9629 3 Skin 0.75 protein_coding missense_variant MODERATE 1070T>C Ile357Thr
M0024836 HFHMMHDH_00015 13264 4 Skin 1.00 protein_coding missense_variant MODERATE 112C>G Leu38Val
M0024837 HFHMMHDH_00018 15009 4 Skin 1.00 protein_coding missense_variant MODERATE 3379T>C Ser1127Pro
M0024838 HFHMMHDH_00018 15163 4 Skin 1.00 protein_coding synonymous_variant LOW 3225T>C Arg1075Arg
M0024839 HFHMMHDH_00018 16072 3 Skin 0.75 protein_coding synonymous_variant LOW 2316T>C Ala772Ala
M0024840 HFHMMHDH_00001 142 3 Skin 0.75 protein_coding synonymous_variant LOW 126T>C Gly42Gly
M0024841 HFHMMHDH_00002 865 3 Skin 0.75 protein_coding missense_variant MODERATE 11G>T Gly4Val
M0024842 HFHMMHDH_00002 1472 3 Skin 0.75 protein_coding missense_variant MODERATE 618C>G Ile206Met
M0024843 HFHMMHDH_00005 4443 3 Skin 0.75 protein_coding missense_variant MODERATE 71T>C Ile24Thr
M0024844 HFHMMHDH_00013 10711 3 Skin 0.75 protein_coding missense_variant MODERATE 43T>G Ser15Ala
M0024845 HFHMMHDH_00013 10712 3 Skin 0.75 protein_coding missense_variant MODERATE 44C>T Ser15Phe
M0024846 HFHMMHDH_00013 10723 3 Skin 0.75 protein_coding missense_variant MODERATE 55T>C Trp19Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term