Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2106
  Reference Plasmid   1111525849742850_bin.52__k141_710520
  Reference Plasmid Size   15205
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025031 IDMLLNJO_00018 10776 3 Skin 0.09 protein_coding synonymous_variant LOW 462G>A Ser154Ser
M0025032 IDMLLNJO_00018 10798 11 Skin 0.32 protein_coding missense_variant MODERATE 484C>G Arg162Gly
M0025033 IDMLLNJO_00019 11490 6 Skin 0.18 protein_coding missense_variant MODERATE 520G>A Val174Ile
M0025034 IDMLLNJO_00020 12230 11 Skin 0.32 protein_coding missense_variant MODERATE 442G>T Gly148Trp
M0025035 IDMLLNJO_00012 6336 15 Skin 0.44 protein_coding stop_lost&splice_region_variant HIGH 436T>C Ter146Argext*?
M0025036 IDMLLNJO_00012 6345 15 Skin 0.44 protein_coding missense_variant MODERATE 427C>A Pro143Thr
M0025037 IDMLLNJO_00012 6354 15 Skin 0.44 protein_coding missense_variant MODERATE 418T>C Ser140Pro
M0025038 IDMLLNJO_00012 6362 15 Skin 0.44 protein_coding missense_variant MODERATE 410G>A Gly137Asp
M0025039 IDMLLNJO_00006 7575 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -4316A>G None
M0025040 IDMLLNJO_00009 8654 4 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -3879C>T None
M0025041 IDMLLNJO_00015 9013 13 Skin 0.38 protein_coding synonymous_variant LOW 220T>C Leu74Leu
M0025042 IDMLLNJO_00018 10550 4 Skin 0.12 protein_coding missense_variant MODERATE 236A>G Gln79Arg
M0025043 IDMLLNJO_00018 10556 4 Skin 0.12 protein_coding missense_variant MODERATE 242A>G Asp81Gly
M0025044 IDMLLNJO_00021 13582 4 Skin 0.12 protein_coding synonymous_variant LOW 265C>T Leu89Leu
M0025045 IDMLLNJO_00021 13593 4 Skin 0.12 protein_coding synonymous_variant LOW 276C>G Thr92Thr
M0025046 IDMLLNJO_00016 9856 9 Skin 0.26 protein_coding synonymous_variant LOW 141T>C Ala47Ala
M0025047 IDMLLNJO_00004 4833 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2807G>T None
M0025048 IDMLLNJO_00003 756 7 Skin 0.21 protein_coding missense_variant MODERATE 65T>C Leu22Pro
M0025049 IDMLLNJO_00003 763 7 Skin 0.21 protein_coding synonymous_variant LOW 72A>G Arg24Arg
M0025050 IDMLLNJO_00003 765 7 Skin 0.21 protein_coding missense_variant MODERATE 74T>C Met25Thr
M0025051 IDMLLNJO_00003 770 7 Skin 0.21 protein_coding missense_variant MODERATE 79G>A Ala27Thr
M0025052 IDMLLNJO_00004 1900 4 Skin 0.12 protein_coding missense_variant MODERATE 127T>G Phe43Val
M0025053 IDMLLNJO_00006 2589 4 Skin 0.12 protein_coding missense_variant MODERATE 671T>C Val224Ala
M0025054 IDMLLNJO_00010 4901 3 Skin 0.09 protein_coding missense_variant MODERATE 539C>T Pro180Leu
M0025055 IDMLLNJO_00011 6130 5 Skin 0.15 protein_coding synonymous_variant LOW 168C>T Thr56Thr
M0025056 IDMLLNJO_00020 12214 3 Skin 0.09 protein_coding synonymous_variant LOW 426C>A Arg142Arg
M0025057 IDMLLNJO_00020 12247 3 Skin 0.09 protein_coding synonymous_variant LOW 459A>G Gly153Gly
M0025058 IDMLLNJO_00020 12257 3 Skin 0.09 protein_coding synonymous_variant LOW 469C>T Leu157Leu
M0025059 IDMLLNJO_00020 12259 3 Skin 0.09 protein_coding synonymous_variant LOW 471A>G Leu157Leu
M0025060 IDMLLNJO_00020 12715 3 Skin 0.09 protein_coding synonymous_variant LOW 927C>G Arg309Arg
M0025061 IDMLLNJO_00020 12730 3 Skin 0.09 protein_coding synonymous_variant LOW 942C>G Thr314Thr
M0025062 IDMLLNJO_00020 12749 3 Skin 0.09 protein_coding synonymous_variant LOW 961C>T Leu321Leu
M0025063 IDMLLNJO_00020 12769 3 Skin 0.09 protein_coding synonymous_variant LOW 981G>T Pro327Pro
M0025064 IDMLLNJO_00020 12775 3 Skin 0.09 protein_coding synonymous_variant LOW 987A>G Arg329Arg
M0025065 IDMLLNJO_00020 12776 3 Skin 0.09 protein_coding missense_variant MODERATE 988C>G Gln330Glu
M0025066 IDMLLNJO_00020 12779 3 Skin 0.09 protein_coding missense_variant MODERATE 991G>A Asp331Asn
M0025067 IDMLLNJO_00020 12791 5 Skin 0.15 protein_coding synonymous_variant LOW 1003T>C Leu335Leu
M0025068 IDMLLNJO_00020 13263 5 Skin 0.15 protein_coding missense_variant MODERATE 1475C>T Ala492Val
M0025069 IDMLLNJO_00021 13629 3 Skin 0.09 protein_coding synonymous_variant LOW 312C>G Leu104Leu
M0025070 IDMLLNJO_00018 10911 3 Skin 0.09 protein_coding synonymous_variant LOW 597A>C Ala199Ala
M0025071 IDMLLNJO_00018 10914 3 Skin 0.09 protein_coding synonymous_variant LOW 600T>C Ala200Ala
M0025072 IDMLLNJO_00019 11000 3 Skin 0.09 protein_coding synonymous_variant LOW 30G>T Ser10Ser
M0025073 IDMLLNJO_00010 4885 3 Skin 0.09 protein_coding missense_variant MODERATE 555A>G Ile185Met
M0025074 IDMLLNJO_00011 5598 3 Skin 0.09 protein_coding synonymous_variant LOW 700C>T Leu234Leu
M0025075 IDMLLNJO_00011 6080 3 Skin 0.09 protein_coding missense_variant MODERATE 218C>T Ala73Val
M0025076 IDMLLNJO_00012 6611 3 Skin 0.09 protein_coding missense_variant MODERATE 161C>T Ala54Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term