Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2108
  Reference Plasmid   1111525849742957_bin.25__k141_44606
  Reference Plasmid Size   19192
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025259 BNMEMFOL_00015 17302 60 Skin 0.77 protein_coding synonymous_variant LOW 765T>A Pro255Pro
M0025260 BNMEMFOL_00014 15998 7 Skin 0.09 protein_coding missense_variant MODERATE 835G>C Val279Leu
M0025261 BNMEMFOL_00013 19057 5 Skin 0.06 protein_coding downstream_gene_variant MODIFIER *4192G>C None
M0025262 BNMEMFOL_00013 11770 16 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -1050C>G None
M0025263 BNMEMFOL_00013 11782 16 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -1038C>A None
M0025264 BNMEMFOL_00013 11783 16 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -1037T>G None
M0025265 BNMEMFOL_00013 13706 3 Skin 0.04 protein_coding missense_variant MODERATE 887C>T Ala296Val
M0025266 BNMEMFOL_00015 18022 3 Skin 0.04 protein_coding synonymous_variant LOW 1485G>C Val495Val
M0025267 BNMEMFOL_00015 18028 3 Skin 0.04 protein_coding synonymous_variant LOW 1491C>G Leu497Leu
M0025268 BNMEMFOL_00015 18035 3 Skin 0.04 protein_coding missense_variant MODERATE 1498A>G Lys500Glu
M0025269 BNMEMFOL_00015 18037 3 Skin 0.04 protein_coding missense_variant MODERATE 1500G>C Lys500Asn
M0025270 BNMEMFOL_00015 18042 3 Skin 0.04 protein_coding missense_variant MODERATE 1505A>G Glu502Gly
M0025271 BNMEMFOL_00015 18043 3 Skin 0.04 protein_coding missense_variant MODERATE 1506G>C Glu502Asp
M0025272 BNMEMFOL_00015 18044 3 Skin 0.04 protein_coding missense_variant MODERATE 1507A>G Ile503Val
M0025273 BNMEMFOL_00015 18049 3 Skin 0.04 protein_coding synonymous_variant LOW 1512G>A Lys504Lys
M0025274 BNMEMFOL_00015 18052 3 Skin 0.04 protein_coding synonymous_variant LOW 1515A>C Pro505Pro
M0025275 BNMEMFOL_00015 18056 3 Skin 0.04 protein_coding missense_variant MODERATE 1519A>G Ile507Val
M0025276 BNMEMFOL_00015 18076 4 Skin 0.05 protein_coding synonymous_variant LOW 1539G>A Gln513Gln
M0025277 BNMEMFOL_00015 18127 3 Skin 0.04 protein_coding synonymous_variant LOW 1590T>C Ile530Ile
M0025278 BNMEMFOL_00015 18142 3 Skin 0.04 protein_coding synonymous_variant LOW 1605T>A Val535Val
M0025279 BNMEMFOL_00015 18163 3 Skin 0.04 protein_coding synonymous_variant LOW 1626T>C Gly542Gly
M0025280 BNMEMFOL_00015 17869 3 Skin 0.04 protein_coding synonymous_variant LOW 1332T>C Pro444Pro
M0025281 BNMEMFOL_00015 17896 3 Skin 0.04 protein_coding synonymous_variant LOW 1359A>G Pro453Pro
M0025282 BNMEMFOL_00015 17914 3 Skin 0.04 protein_coding synonymous_variant LOW 1377T>C Ser459Ser
M0025283 BNMEMFOL_00015 17921 3 Skin 0.04 protein_coding missense_variant MODERATE 1384G>A Val462Met
M0025284 BNMEMFOL_00015 17923 3 Skin 0.04 protein_coding synonymous_variant LOW 1386G>C Val462Val
M0025285 BNMEMFOL_00015 17926 3 Skin 0.04 protein_coding synonymous_variant LOW 1389T>C Val463Val
M0025286 BNMEMFOL_00015 17932 3 Skin 0.04 protein_coding synonymous_variant LOW 1395G>C Leu465Leu
M0025287 BNMEMFOL_00015 17938 3 Skin 0.04 protein_coding synonymous_variant LOW 1401T>G Leu467Leu
M0025288 BNMEMFOL_00015 17953 3 Skin 0.04 protein_coding synonymous_variant LOW 1416A>G Ala472Ala
M0025289 BNMEMFOL_00015 17143 4 Skin 0.05 protein_coding synonymous_variant LOW 606T>C Arg202Arg
M0025290 BNMEMFOL_00015 17155 3 Skin 0.04 protein_coding synonymous_variant LOW 618T>C Gly206Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BNMEMFOL_00004 AXQ49465.1|GT2 99.7 1.2e-231 1 320 1 1
BNMEMFOL_00008 ABZ00243.1|GT0 95 0 1 1038 0.9933 0.9895





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term