Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2111
  Reference Plasmid   1111525849742984_bin.17__k141_178354
  Reference Plasmid Size   6652
  Reference Plasmid GC Content   0.49
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0025294 JPKHAOLD_00001 478 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -160A>G None
M0025295 JPKHAOLD_00002 1780 7 Skin 0.70 protein_coding missense_variant MODERATE 22G>A Val8Ile
M0025296 JPKHAOLD_00003 2316 3 Skin 0.30 protein_coding synonymous_variant LOW 354A>G Lys118Lys
M0025297 JPKHAOLD_00004 3049 7 Skin 0.70 protein_coding synonymous_variant LOW 340C>T Leu114Leu
M0025298 JPKHAOLD_00005 4113 4 Skin 0.40 protein_coding missense_variant MODERATE 509T>C Val170Ala
M0025299 JPKHAOLD_00005 4186 6 Skin 0.60 protein_coding synonymous_variant LOW 582A>C Ile194Ile
M0025300 JPKHAOLD_00002 1838 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -37G>A None
M0025301 JPKHAOLD_00003 2601 3 Skin 0.30 protein_coding synonymous_variant LOW 639C>T Arg213Arg
M0025302 JPKHAOLD_00002 3439 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1638G>A None
M0025303 JPKHAOLD_00002 3451 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1650C>A None
M0025304 JPKHAOLD_00002 3464 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1663G>T None
M0025305 JPKHAOLD_00005 3641 4 Skin 0.40 protein_coding missense_variant MODERATE 37G>A Val13Ile
M0025306 JPKHAOLD_00005 3643 4 Skin 0.40 protein_coding synonymous_variant LOW 39A>G Val13Val
M0025307 JPKHAOLD_00005 3676 4 Skin 0.40 protein_coding synonymous_variant LOW 72C>T Pro24Pro
M0025308 JPKHAOLD_00005 3685 4 Skin 0.40 protein_coding synonymous_variant LOW 81T>C Ser27Ser
M0025309 JPKHAOLD_00005 3686 4 Skin 0.40 protein_coding missense_variant MODERATE 82T>A Ser28Thr
M0025310 JPKHAOLD_00002 1709 5 Skin 0.50 protein_coding synonymous_variant LOW 93A>T Ala31Ala
M0025311 JPKHAOLD_00002 1736 5 Skin 0.50 protein_coding synonymous_variant LOW 66T>C Arg22Arg
M0025312 JPKHAOLD_00006 5039 3 Skin 0.30 protein_coding missense_variant MODERATE 794A>T Gln265Leu
M0025313 JPKHAOLD_00002 5554 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -3753G>T None
M0025314 JPKHAOLD_00002 5556 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -3755G>T None
M0025315 JPKHAOLD_00002 5565 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -3764C>T None
M0025316 JPKHAOLD_00002 5571 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -3770C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term